MPRIP(2-1015)-p-RAF1(279-648) fusion [cytosol]

Stable Identifier
R-HSA-6802540
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Literature References
PubMed ID Title Journal Year
25204415 The landscape of kinase fusions in cancer

Kim, JL, Schalm, S, Stransky, N, Lengauer, C, Cerami, E

Nat Commun 2014
External Reference Information
External Reference
UniProt:Q6WCQ1 MPRIP
Gene Names
MPRIP, KIAA0864, MRIP, RHOIP3
Chain
initiator methionine:, chain:2-1025
Reference Genes
BioGPS Gene:23164 MPRIP
COSMIC (genes):MPRIP MPRIP
CTD Gene:23164 MPRIP
dbSNP Gene:23164 MPRIP
ENSEMBL:ENSG00000133030 MPRIP
ENSEMBL_homo_sapiens_GENE:ENSG00000133030.22 MPRIP
HGNC:30321 MPRIP
KEGG Gene (Homo sapiens):23164 MPRIP
Monarch:23164 MPRIP
NCBI Gene:23164 MPRIP
OMIM:612935 MPRIP
UCSC:Q6WCQ1 MPRIP
Reference Transcript
Other Identifiers
11717546_s_at
11739524_a_at
16831562
212197_PM_x_at
212197_x_at
214694_PM_at
214694_at
214771_PM_x_at
214771_x_at
225896_PM_at
225896_at
23164
238328_PM_at
238328_at
2671507
2671508
2671509
2671510
2671512
2671513
2671514
2671515
2671519
2671520
2671550
3712364
3712365
3712376
3712378
3712397
3712400
3712404
3712405
3712406
3712408
3712413
3712417
3712418
3712419
3712422
3712423
3712427
3712428
3712429
3712431
3712432
3712449
3712450
3712452
3712453
3712455
3712456
3712457
3712459
3712461
3712463
3712464
3712471
3712472
3712473
3712474
3712475
3712476
3712484
3712485
3712486
38730_at
38731_at
51061_at
52146_at
8180362
8180363
A_19_P00317887
A_19_P00803575
A_19_P00811812
A_23_P15348
A_32_P105976
D23673_at
GE53547
GO:0003779
GO:0005515
GO:0005737
GO:0005829
GO:0005856
GO:0005925
GO:0008092
GO:0015629
GO:0043226
GO:0045296
GO:0051015
HMNXSV003006205
Hs.159336.0.A1_3p_at
Hs.46783.0.S1_3p_at
Hs.84883.0.A1_3p_a_at
ILMN_1678692
ILMN_1774547
ILMN_1836776
ILMN_1905780
PH_hs_0025217
TC17000194.hg
TC17002083.hg
TC17002084.hg
Participates
as a component of
Other forms of this molecule
MPRIP(2-1015)-RAF1(279-648) fusion [cytosol]
Modified Residues
Name
Insertion of residues 279 to 648 at 1016 from UniProt:P04049 RAF1
Coordinate
1016
Name
O-phospho-L-serine at 621
Coordinate
621
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 338
Coordinate
338
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O4'-phospho-L-tyrosine at 341
Coordinate
341
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O-phospho-L-threonine at 491
Coordinate
491
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-serine at 494
Coordinate
494
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Disease
Name Identifier Synonyms
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
skin melanoma DOID:8923 malignant lip melanoma, malignant ear melanoma, malignant melanoma of ear and/or external auricular canal, cutaneous melanoma, malignant melanoma of skin of trunk except scrotum, malignant neck melanoma, malignant melanoma of skin of upper limb, malignant scalp melanoma, malignant upper limb melanoma, malignant lower limb melanoma, malignant melanoma of skin of lower limb, malignant trunk melanoma
Cross References
RefSeq
OpenTargets
GeneCards
HPA
Ensembl
PRO
Pharos - Targets
Interactors (5)
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