Reactome | S100A9 [secretory granule lumen]

S100A9 [secretory granule lumen]

Stable Identifier

R-HSA-6804774

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

secretory granule lumen

Synonyms

calgranulin-B, calprotectin L1H subunit, S100 calcium-binding protein A9

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P06702 S100A9

Gene Names

S100A9, CAGB, CFAG, MRP14

Chain

chain:1-114

Reference Genes

BioGPS Gene:6280 S100A9

COSMIC (genes):S100A9 S100A9

CTD Gene:6280 S100A9

dbSNP Gene:6280 S100A9

ENSEMBL:ENSG00000163220 S100A9

ENSEMBL_homo_sapiens_GENE:ENSG00000163220.11 S100A9

HGNC:10499 S100A9

KEGG Gene (Homo sapiens):6280 S100A9

Monarch:6280 S100A9

NCBI Gene:6280 S100A9

OMIM:123886 S100A9

UCSC:P06702 S100A9

Reference Transcript

RefSeq:NM_002965.3 S100A9

Other Identifiers

11716523_at

16671139

203535_PM_at

203535_at

2359665

2359666

2359667

2359668

2359669

2359670

41471_at

6280

7905571

ADDON002818.hg

A_23_P23048

GE80079

GO:0002376

GO:0002523

GO:0002544

GO:0005509

GO:0005515

GO:0005576

GO:0005615

GO:0005634

GO:0005737

GO:0005829

GO:0005856

GO:0005886

GO:0006351

GO:0006355

GO:0006914

GO:0006915

GO:0006919

GO:0006935

GO:0006954

GO:0007010

GO:0007155

GO:0007267

GO:0008017

GO:0008092

GO:0008270

GO:0008289

GO:0010976

GO:0012501

GO:0014002

GO:0016020

GO:0016209

GO:0023052

GO:0030154

GO:0030307

GO:0030312

GO:0030593

GO:0031012

GO:0031410

GO:0032119

GO:0032496

GO:0034121

GO:0034774

GO:0035425

GO:0035606

GO:0035662

GO:0035821

GO:0036211

GO:0042742

GO:0043226

GO:0043542

GO:0045087

GO:0045113

GO:0046872

GO:0048306

GO:0048856

GO:0048870

GO:0050544

GO:0050729

GO:0050786

GO:0050832

GO:0051092

GO:0051493

GO:0055065

GO:0060264

GO:0061024

GO:0061844

GO:0062023

GO:0070062

GO:0070488

GO:0098542

GO:0098754

GO:0098869

GO:1990660

GO:1990662

GO:2001244

ILMN_1750974

M26311_s_at

PH_hs_0006160

TC01001254.hg

g9845520_3p_at

Participates

as a member of

Secretory granule lumen proteins [secretory granule lumen] (Homo sapiens)

Other forms of this molecule

S100A9 [cytosol]

S100A9 [extracellular region]

Inferred To

S100A9 [secretory granule lumen] (Bos taurus)

S100A9 [secretory granule lumen] (Canis familiaris)

S100A9 [secretory granule lumen] (Gallus gallus)

S100A9 [secretory granule lumen] (Mus musculus)

S100A9 [secretory granule lumen] (Rattus norvegicus)

S100A9 [secretory granule lumen] (Sus scrofa)

s100a10a [secretory granule lumen] (Danio rerio)

s100a10b [secretory granule lumen] (Danio rerio)

Homologues of S100A9 [secretory granule lumen] (Danio rerio)

s100a11 [secretory granule lumen] (Xenopus tropicalis)

Cross References

RefSeq

NP_002956.1

OpenTargets

ENSG00000163220

HPA

ENSG00000163220-S100A9

GeneCards

P06702

Ensembl

ENSG00000163220, ENST00000368738, ENSP00000357727

PRO

P06702

Pharos - Targets

P06702

HMDB Protein

HMDBP02286

PDB

5I8N, 4GGF, 7UI5, 7QUV, 5W1F, 1IRJ, 4XJK, 1XK4, 6DS2

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.774	15
UniProt:P04271 S100B	1	S100B [extracellular region] (R-HSA-879433)	0.556	3
UniProt:Q15915 ZIC1	1	ZIC1 [nucleoplasm] (R-HSA-9731648)	0.527	2
UniProt:P49407 ARRB1	6	ARRB1 [cytosol] (R-HSA-264470) PolyUb-ARRB1 [cytosol] (R-HSA-6783186) ARRB1 [endocytic vesicle membrane] (R-HSA-9910882) ARRB1 [lysosomal membrane] (R-HSA-432701) ARRB1 [Golgi membrane] (R-HSA-350831) ARRB1 [cytoplasmic vesicle membrane] (R-HSA-351187)	0.499	2
UniProt:P32121 ARRB2	3	ARRB2 [cytosol] (R-HSA-416464) PolyUb-ARRB2 [cytosol] (R-HSA-6783000) ARRB2 [endocytic vesicle membrane] (R-HSA-9910881)	0.499	2
UniProt:P35228 NOS2	3	NOS2 [peroxisomal matrix] (R-HSA-9033124) NOS2 [nucleoplasm] (R-HSA-9636250) NOS2 [cytosol] (R-HSA-202107)	0.462	7

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