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LCE4A [cytosol]
Stable Identifier
R-HSA-6814272
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Late cornified envelope protein 4A, LCE4A_HUMAN
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Keratinization (Homo sapiens)
Formation of the cornified envelope (Homo sapiens)
CASP14 cleaves filaggrin (Homo sapiens)
Late cornified envelope [plasma membrane] (Homo sapiens)
Late envelope proteins [cytosol] (Homo sapiens)
LCE4A [cytosol] (Homo sapiens)
Mature cornified envelope [plasma membrane] (Homo sapiens)
Late envelope proteins [cytosol] (Homo sapiens)
LCE4A [cytosol] (Homo sapiens)
Late envelope proteins bind cornified envelope:CDSN (Homo sapiens)
Late cornified envelope [plasma membrane] (Homo sapiens)
Late envelope proteins [cytosol] (Homo sapiens)
LCE4A [cytosol] (Homo sapiens)
Late envelope proteins [cytosol] (Homo sapiens)
LCE4A [cytosol] (Homo sapiens)
Plasma membrane resorption (Homo sapiens)
Mature cornified envelope [cornified envelope] (Homo sapiens)
Late envelope proteins [cytosol] (Homo sapiens)
LCE4A [cytosol] (Homo sapiens)
Mature cornified envelope [plasma membrane] (Homo sapiens)
Late envelope proteins [cytosol] (Homo sapiens)
LCE4A [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q5TA78 LCE4A
Gene Names
LCE4A, LEP8, SPRL4A
Chain
chain:1-99
Reference Genes
BioGPS Gene:199834 LCE4A
COSMIC (genes):LCE4A LCE4A
CTD Gene:199834 LCE4A
dbSNP Gene:199834 LCE4A
ENSEMBL:ENSG00000187170 LCE4A
HGNC:16613 LCE4A
Monarch:199834 LCE4A
NCBI Gene:199834 LCE4A
OMIM:612618 LCE4A
UCSC:Q5TA78 LCE4A
Reference Transcript
RefSeq:NM_178356.3 LCE4A
Other Identifiers
11735842_at
16671053
199834
2359385
2359387
2359388
2359389
2359390
2359391
2359392
2359393
7905510
ADDON002690.hg
A_23_P310540
A_33_P3226109
GO:0005515
GO:0008544
GO:0031424
GO:0042802
GO:0048856
HMNXSV003034939
ILMN_1806683
TC01001234.hg
Participates
as a candidate of
Late envelope proteins [cytosol] (Homo sapiens)
Cross References
ENSEMBL
ENST00000368777
,
ENSP00000357766
OpenTargets
ENSG00000187170
HPA
ENSG00000187170-LCE4A
PRO
Q5TA78
Pharos - Targets
Q5TA78
Interactors (8)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P49639 HOXA1
1
HOXA1 [nucleoplasm]
(R-HSA-5617464)
0.718
9
UniProt:Q6ZNA4 RNF111
2
RNF111 [cytosol]
(R-HSA-975981)
RNF111 [nucleoplasm]
(R-HSA-2186765)
0.556
3
UniProt:O43597 SPRY2
8
p-S112,S115-SPRY2 [cytosol]
(R-HSA-1295619)
SPRY2 [cytosol]
(R-HSA-182949)
SPRY2 [plasma membrane]
(R-HSA-182924)
p-S112,S121-SPRY2 [plasma membrane]
(R-HSA-934595)
p-Y55,Y227-SPRY2 [plasma membrane]
(R-HSA-934555)
p-S111,S120-SPRY2 [cytosol]
(R-HSA-1295590)
p-Y55,Y227-SPRY2 [plasma membrane]
(R-HSA-1295629)
p-Y55-SPRY2 [cytosol]
(R-HSA-182950)
0.556
3
UniProt:Q92504 SLC39A7
1
SLC39A7 [endoplasmic reticulum membrane]
(R-HSA-442363)
0.556
3
UniProt:Q9H2F3 HSD3B7
1
HSD3B7 [endoplasmic reticulum membrane]
(R-HSA-193441)
0.556
3
UniProt:P0DPK4 NOTCH2NLC
1
NOTCH2NLC [extracellular region]
(R-HSA-9908932)
0.556
3
UniProt:P07237 P4HB
3
P4HB [endoplasmic reticulum lumen]
(R-HSA-174692)
p-P4HB [endoplasmic reticulum lumen]
(R-HSA-8956902)
HC53,56-P4HB [endoplasmic reticulum lumen]
(R-HSA-3341287)
0.556
3
UniProt:P22735 TGM1
3
TGM1 [cytosol]
(R-HSA-6813756)
TGM1 [cornified envelope]
(R-HSA-8847706)
TGM1 [plasma membrane]
(R-HSA-6813757)
0.556
3
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