Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
SNAP23 [plasma membrane]
Stable Identifier
R-HSA-376345
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Synaptosomal-associated protein 23, SNP23_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of specific granule membrane proteins (Homo sapiens)
Specific granule membrane proteins [plasma membrane] (Homo sapiens)
SNAP23 [plasma membrane] (Homo sapiens)
Exocytosis of tertiary granule membrane proteins (Homo sapiens)
Tertiary granule membrane proteins [plasma membrane] (Homo sapiens)
SNAP23 [plasma membrane] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Translocation of SLC2A4 (GLUT4) to the plasma membrane (Homo sapiens)
SLC2A4 (GLUT4) vesicle fuses with the plasma membrane (Homo sapiens)
SNAP23 [plasma membrane] (Homo sapiens)
VAMP2:STX4:SNAP23 [plasma membrane] (Homo sapiens)
SNAP23 [plasma membrane] (Homo sapiens)
trans-Golgi Network Vesicle Budding (Homo sapiens)
Vamp2 associated secretory vesicle to plasma membrane transport (Homo sapiens)
SNAP23 [plasma membrane] (Homo sapiens)
Vamp2:SNAP23:Syn4 Secretory granule docking and fusion complex [plasma membrane] (Homo sapiens)
SNAP23 [plasma membrane] (Homo sapiens)
Vamp7 associated Lysosome to Plasma membrane transport (Homo sapiens)
SNAP23 [plasma membrane] (Homo sapiens)
Vamp7:SNAP23:Syn4 Plasma membrane vesicle docking and fusion complex [plasma membrane] (Homo sapiens)
SNAP23 [plasma membrane] (Homo sapiens)
Vamp8 associated secretory vesicle to plasma membrane transport (Homo sapiens)
SNAP23 [plasma membrane] (Homo sapiens)
Vamp8:SNAP23:Syn4 Secretory granule docking and fusion complex [plasma membrane] (Homo sapiens)
SNAP23 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O00161 SNAP23
Gene Names
SNAP23
Chain
chain:1-211
Reference Genes
BioGPS Gene:8773 SNAP23
COSMIC (genes):SNAP23 SNAP23
CTD Gene:8773 SNAP23
dbSNP Gene:8773 SNAP23
ENSEMBL:ENSG00000092531 SNAP23
HGNC:11131 SNAP23
KEGG Gene (Homo sapiens):8773 SNAP23
Monarch:8773 SNAP23
NCBI Gene:8773 SNAP23
OMIM:602534 SNAP23
UCSC:O00161 SNAP23
Reference Transcript
RefSeq:NM_003825.3 SNAP23
RefSeq:NM_130798.2 SNAP23
Other Identifiers
0001570373
0002340435
11739173_a_at
11739174_x_at
11741581_s_at
11753568_x_at
11757831_x_at
16800095
209130_at
209131_s_at
214544_s_at
32178_r_at
32179_s_at
3591008
3591013
3591014
3591015
3591019
3591020
3591027
3591028
3591031
3591032
3591033
3591034
46749_i_at
7983111
8773
A_23_P206177
A_33_P3305974
GE81326
GO:0002376
GO:0002479
GO:0002553
GO:0003674
GO:0005484
GO:0005515
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005634
GO:0005654
GO:0005737
GO:0005739
GO:0005764
GO:0005773
GO:0005886
GO:0005912
GO:0005925
GO:0006810
GO:0006887
GO:0006892
GO:0006903
GO:0006906
GO:0006950
GO:0007267
GO:0008150
GO:0015031
GO:0016020
GO:0016082
GO:0016192
GO:0019905
GO:0022607
GO:0030054
GO:0030670
GO:0030674
GO:0031201
GO:0031410
GO:0031629
GO:0032991
GO:0035579
GO:0042581
GO:0042582
GO:0042629
GO:0043005
GO:0043226
GO:0043312
GO:0045202
GO:0061024
GO:0061025
GO:0065003
GO:0070062
GO:0070821
GO:0098793
ILMN_1687519
ILMN_1748911
PH_hs_0023005
TC15000320.hg
U55936_at
g13277555_3p_at
g1374812_3p_a_at
Participant Of
output
Vamp2 associated secretory vesicle to plasma membrane transport
Vamp7 associated Lysosome to Plasma membrane transport
Vamp8 associated secretory vesicle to plasma membrane transport
input
SLC2A4 (GLUT4) vesicle fuses with the plasma membrane
Vamp2 associated secretory vesicle to plasma membrane transport
Vamp7 associated Lysosome to Plasma membrane transport
Vamp8 associated secretory vesicle to plasma membrane transport
hasComponent
Vamp2:SNAP23:Syn4 Secretory granule docking and fusion complex [plasma membrane]
VAMP2:STX4:SNAP23 [plasma membrane]
Vamp7:SNAP23:Syn4 Plasma membrane vesicle docking and fusion complex [plasma membrane]
Vamp8:SNAP23:Syn4 Secretory granule docking and fusion complex [plasma membrane]
hasMember
Specific granule membrane proteins [plasma membrane]
Tertiary granule membrane proteins [plasma membrane]
Other forms of this molecule
SNAP23 [specific granule membrane]
SNAP23 [tertiary granule membrane]
p-S95-SNAP23 [phagocytic vesicle membrane]
SNAP23 [phagocytic vesicle membrane]
Inferred To
SEC9 [plasma membrane] (Saccharomyces cerevisiae)
Snap23 [plasma membrane] (Mus musculus)
snap23.1 [plasma membrane] (Danio rerio)
SPO20 [plasma membrane] (Saccharomyces cerevisiae)
SNAP23 [plasma membrane] (Bos taurus)
SNAP23 [plasma membrane] (Canis familiaris)
SNAP23 [plasma membrane] (Dictyostelium discoideum)
SNAP23 [plasma membrane] (Gallus gallus)
SNAP23 [plasma membrane] (Plasmodium falciparum)
SNAP23 [plasma membrane] (Sus scrofa)
culC [plasma membrane] (Dictyostelium discoideum)
pop5 [plasma membrane] (Xenopus tropicalis)
Snap25 [plasma membrane] (Drosophila melanogaster)
ric-4 [plasma membrane] (Caenorhabditis elegans)
Homologues of SNAP23 [plasma membrane] (Dictyostelium discoideum)
Homologues of SNAP23 [plasma membrane] (Saccharomyces cerevisiae)
sec9 [plasma membrane] (Schizosaccharomyces pombe)
Cross References
RefSeq
NP_003816.2
,
NP_570710.1
OpenTargets
ENSG00000092531
HPA
ENSG00000092531-SNAP23
GeneCards
O00161
Ensembl
ENST00000249647
,
ENSP00000380327
,
ENSP00000207062
,
ENSP00000249647
,
ENST00000397138
,
ENST00000349777
,
ENSG00000092531
PRO
O00161
PDB
1NHL
,
3ZUS
Interactors (8)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O75558 STX11
0.83
10
UniProt:P54920 NAPA
1
NAPA [cytosol]
(R-HSA-264469)
0.632
3
UniProt:Q15836 VAMP3
6
VAMP3 [phagocytic vesicle membrane]
(R-HSA-2029013)
VAMP3 [recycling endosome membrane]
(R-HSA-2029063)
VAMP3 [trans-Golgi network membrane]
(R-HSA-6814624)
VAMP3 [transport vesicle]
(R-HSA-6814625)
VAMP3 [plasma membrane]
(R-HSA-8867599)
VAMP3 [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869130)
0.564
2
UniProt:Q9H115 NAPB
1
NAPB [cytosol]
(R-HSA-5688553)
0.556
3
UniProt:Q16623 STX1A
6
STX1A [plasma membrane]
(R-HSA-6794231)
STX1A [plasma membrane]
(R-HSA-449128)
STX1A(?-288) [plasma membrane]
(R-HSA-5246518)
STX1A(1-?) [cytosol]
(R-HSA-3065964)
STX1A [cytosol]
(R-HSA-9609866)
STX1A [endoplasmic reticulum membrane]
(R-HSA-9609878)
0.553
2
UniProt:P56962 STX17
1
STX17 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-6807769)
0.524
2
UniProt:Q8IUH5 ZDH17
0.508
4
UniProt:O15155 BET1
3
BET1 [transport vesicle]
(R-HSA-6808719)
BET1 [Golgi membrane]
(R-HSA-6807743)
BET1 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-5688142)
0.462
2
© 2021
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text