Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
MVP [extracellular region]
Stable Identifier
R-HSA-6806474
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Major vault protein, MVP_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of ficolin-rich granule lumen proteins (Homo sapiens)
Ficolin-rich granule lumen proteins [extracellular region] (Homo sapiens)
MVP [extracellular region] (Homo sapiens)
Exocytosis of secretory granule lumen proteins (Homo sapiens)
Secretory granule lumen proteins [extracellular region] (Homo sapiens)
MVP [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q14764 MVP
Gene Names
MVP, LRP
Chain
initiator methionine:, chain:2-893
Reference Genes
BioGPS Gene:9961 MVP
COSMIC (genes):MVP MVP
CTD Gene:9961 MVP
dbSNP Gene:9961 MVP
ENSEMBL:ENSG00000013364 MVP
HGNC:7531 MVP
KEGG:hsa:9961 MVP
Monarch:9961 MVP
NCBI Gene:9961 MVP
OMIM:605088 MVP
UCSC:Q14764 MVP
Reference Transcript
RefSeq:NM_017458.3 MVP
RefSeq:NM_001293204.1 MVP
RefSeq:NM_001293205.1 MVP
RefSeq:NM_005115.4 MVP
Other Identifiers
11716135_a_at
11749978_a_at
16817692
202180_PM_s_at
202180_s_at
3655716
3655724
3655725
3655726
3655727
3655728
3655729
3655730
3655731
3655732
3655733
3655734
3655735
3655736
3655737
3655738
3655739
3655740
3655741
3655743
3655744
3655745
3655746
3655747
3655748
3655749
3655750
38064_at
7994659
9961
A_23_P88819
A_33_P3294608
GE60057
GO:0005515
GO:0005576
GO:0005634
GO:0005643
GO:0005737
GO:0005829
GO:0005856
GO:0008283
GO:0015031
GO:0016020
GO:0019901
GO:0019903
GO:0031953
GO:0034774
GO:0038127
GO:0042059
GO:0042802
GO:0043226
GO:0048471
GO:0051028
GO:0051604
GO:0061099
GO:0070062
GO:0072376
GO:1904813
GO:1990904
HMNXSV003009533
ILMN_1803277
ILMN_2344373
PH_hs_0004640
TC16002071.hg
X79882_at
g9665254_3p_s_at
Participates
as a member of
Ficolin-rich granule lumen proteins [extracellular region] (Homo sapiens)
Secretory granule lumen proteins [extracellular region] (Homo sapiens)
Other forms of this molecule
MVP [ficolin-1-rich granule lumen]
MVP [secretory granule lumen]
Inferred To
mvp [extracellular region]
(Danio rerio)
mvp [extracellular region]
(Xenopus tropicalis)
mvpA [extracellular region]
(Dictyostelium discoideum)
Mvp [extracellular region]
(Mus musculus)
Mvp [extracellular region]
(Rattus norvegicus)
MVP [extracellular region]
(Bos taurus)
MVP [extracellular region]
(Canis familiaris)
MVP [extracellular region]
(Gallus gallus)
MVP [extracellular region]
(Sus scrofa)
Cross References
ENSEMBL
ENST00000395353
,
ENSP00000378760
,
ENST00000357402
,
ENSP00000349977
OpenTargets
ENSG00000013364
HPA
ENSG00000013364-MVP
PRO
Q14764
Pharos - Targets
Q14764
GlyGen
Q14764
PDB
1Y7X
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9H0E2 TOLLIP
4
TOLLIP [cytosol]
(R-HSA-446885)
TOLLIP [specific granule lumen]
(R-HSA-6799719)
TOLLIP [extracellular region]
(R-HSA-6800448)
TOLLIP [azurophil granule lumen]
(R-HSA-6799709)
0.556
3
UniProt:P13569 CFTR
17
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR [endosome membrane]
(R-HSA-6782965)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [lysosomal membrane]
(R-HSA-5627279)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
0.527
13
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text