Reactome | DOCK7 [cytosol]

DOCK7 [cytosol]

Stable Identifier

R-HSA-1012970

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Dedicator of cytokinesis protein 7, DOCK7_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q96N67 DOCK7

Gene Names

DOCK7, KIAA1771

Chain

chain:1-2140

Reference Genes

BioGPS Gene:85440 DOCK7

COSMIC (genes):DOCK7 DOCK7

CTD Gene:85440 DOCK7

dbSNP Gene:85440 DOCK7

ENSEMBL:ENSG00000116641 DOCK7

ENSEMBL:ENSG00000116641.18 DOCK7

HGNC:19190 DOCK7

KEGG Gene (Homo sapiens):85440 DOCK7

Monarch:85440 DOCK7

NCBI Gene:85440 DOCK7

OMIM:615730 DOCK7

UCSC:Q96N67 DOCK7

Reference Transcript

Other Identifiers

11739883_a_at

11739884_a_at

11739885_s_at

11749664_a_at

11749665_x_at

11753987_x_at

11763209_at

1562940_PM_at

1562940_at

16688024

225384_PM_at

225384_at

237470_PM_at

237470_at

2415911

2415912

2415913

2415914

2415915

2415916

2415919

2415920

2415921

2415922

2415923

2415930

2415933

2415934

2415935

2415937

2415938

2415939

2415940

2415941

2415942

2415944

2415945

2415946

2415947

2415948

2415949

2415950

2415951

2415952

2415953

2415954

2415956

2415957

2415959

2415964

2415965

2415966

2415968

2415971

2415972

2415975

2415976

2415977

2415979

2415980

2415981

2415987

2415988

2415990

2415992

2415993

2415995

2415996

2415998

2416005

2416007

2416008

2416009

2416010

2416011

2416015

48708_at

49128_i_at

49129_r_at

7916669

85440

A_23_P331348

A_24_P203622

A_32_P230547

GE566028

GE85506

GO:0000226

GO:0005085

GO:0005515

GO:0005634

GO:0005925

GO:0007010

GO:0007163

GO:0007264

GO:0007399

GO:0007409

GO:0008180

GO:0022027

GO:0023052

GO:0030154

GO:0030424

GO:0030426

GO:0031175

GO:0031267

GO:0033138

GO:0036211

GO:0042995

GO:0043005

GO:0043226

GO:0043547

GO:0045178

GO:0045200

GO:0048856

GO:0048870

GO:0050767

GO:0090630

GO:0098772

GO:0110165

GO:0120163

GO:1904754

HMNXSV003005424

HMNXSV003013615

Hs.22869.0.A1_3p_at

Hs.93560.0.S1_3p_at

ILMN_1678629

ILMN_2152387

PH_hs_0041018

TC01002727.hg

Participates

as a candidate of

Inferred To

Dock7 [cytosol] (Mus musculus)

Dock7 [cytosol] (Rattus norvegicus)

DOCK7 [cytosol] (Bos taurus)

DOCK7 [cytosol] (Caenorhabditis elegans)

DOCK7 [cytosol] (Canis familiaris)

DOCK7 [cytosol] (Danio rerio)

DOCK7 [cytosol] (Gallus gallus)

DOCK7 [cytosol] (Sus scrofa)

zizD [cytosol] (Dictyostelium discoideum)

Homologues of DOCK7 [cytosol] (Dictyostelium discoideum)

dock7 [cytosol] (Xenopus tropicalis)

zizA [cytosol] (Dictyostelium discoideum)

zizB [cytosol] (Dictyostelium discoideum)

Zir [cytosol] (Drosophila melanogaster)

zizC [cytosol] (Dictyostelium discoideum)

Cross References

RefSeq

XP_011540628.1, NP_001317543.1, NP_001258930.1, NP_001258929.1, NP_212132.2, NP_001258928.1, NP_001258931.1

OpenTargets

ENSG00000116641

GeneCards

Q96N67

HPA

ENSG00000116641-DOCK7

Ensembl

ENSP00000489284, ENST00000634264, ENST00000635253, ENST00000251157, ENSP00000251157, ENSG00000116641, ENST00000340370, ENST00000454575, ENSP00000413583, ENSP00000489499, ENST00000635123, ENSP00000340742, ENSP00000489124, ENST00000404627, ENSP00000384446

PRO

Q96N67

Pharos - Targets

Q96N67

Orphanet

23078

PDB

6AJL, 6AJ4

HMDB Protein

HMDBP08358

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.615	13
UniProt:Q9Y3M2 CBY1	3	pS20-CBY1 [nucleoplasm] (R-HSA-3769356) CBY1 [nucleoplasm] (R-HSA-3769210) pS20-CBY1 [cytosol] (R-HSA-3769354)	0.508	2