NEXT3 [plasma membrane]

Stable Identifier
R-HSA-157203
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
NOTCH3(1629-2321), Notch 3 NEXT fragment
Icon
NEXT3 [plasma membrane] icon
NEXT3 [plasma membrane] icon
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:Q9UM47 NOTCH3
Gene Names
NOTCH3
Chain
signal peptide:1-39, chain:40-2321, chain:1629-2321, chain:1662-2321
Reference Genes
BioGPS Gene:4854 NOTCH3
COSMIC (genes):NOTCH3 NOTCH3
CTD Gene:4854 NOTCH3
dbSNP Gene:4854 NOTCH3
ENSEMBL:ENSG00000074181 NOTCH3
HGNC:7883 NOTCH3
KEGG Gene (Homo sapiens):4854 NOTCH3
Monarch:4854 NOTCH3
NCBI Gene:4854 NOTCH3
OMIM:600276 NOTCH3
UCSC:Q9UM47 NOTCH3
Reference Transcript
Other Identifiers
0001990315
11716569_at
11716570_a_at
16869769
203237_s_at
203238_s_at
3853111
3853112
3853113
3853114
3853115
3853116
3853117
3853118
3853119
3853120
3853121
3853122
3853123
3853124
3853126
3853127
3853128
3853129
3853130
3853131
3853133
3853134
3853135
3853136
3853137
3853138
3853139
3853140
3853141
3853142
3853143
3853145
3853146
3853147
3853148
3853150
3853151
3853152
3853153
3853154
3853157
3853158
3853159
3853160
3853161
3853162
3853163
3853164
3853166
3853167
3853168
3853169
3853170
3853173
3853174
3853175
38750_at
4854
8034940
A_33_P3313055
GE79373
GO:0000139
GO:0000902
GO:0003674
GO:0005509
GO:0005515
GO:0005575
GO:0005576
GO:0005622
GO:0005634
GO:0005654
GO:0005737
GO:0005783
GO:0005789
GO:0005794
GO:0005829
GO:0005856
GO:0005886
GO:0006355
GO:0006367
GO:0007165
GO:0007219
GO:0007221
GO:0007275
GO:0007411
GO:0008150
GO:0009058
GO:0009986
GO:0015629
GO:0016020
GO:0016021
GO:0030154
GO:0032991
GO:0034641
GO:0038023
GO:0040011
GO:0042802
GO:0043167
GO:0043226
GO:0043235
GO:0045296
GO:0045746
GO:0048856
GO:0050793
HMNXSV003010299
Hs.8546.0.A1_3p_a_at
ILMN_1658926
ILMN_1755832
PH_hs_0000907
TC19001250.hg
g4557798_3p_a_at
Participates
as a member of
as an output of
as an input of
Other forms of this molecule
Ub-NICD3 [cytosol]
Ub-NEXT3 [plasma membrane]
p-Y-NICD3 [cytosol]
Glc,GlcNAc-Fuc-Pre-NOTCH3 [Golgi membrane]
Glc,Gal-GlcNAc-Fuc-Pre-NOTCH3 [Golgi membrane]
Glc,Sia-Gal-GlcNAc-Fuc-Pre-NOTCH3 [Golgi membrane]
FRINGE-modified NOTCH3 Extracellular Fragment (NECD3) [plasma membrane]
FRINGE-modified NOTCH3 Extracellular fragment (NECD3) [Golgi membrane]
NOTCH3(40-1628) [extracellular region]
NOTCH3(1629-1661) [plasma membrane]
NICD3 [cytosol]
NICD3 [nucleoplasm]
Pre-NOTCH3 [endoplasmic reticulum membrane]
10xFucT-4xFucS-NOTCH3(40-2321) [endoplasmic reticulum membrane]
14xGlcS-10xFucT-4xFucS-NOTCH3(40-2321) [endoplasmic reticulum membrane]
14xGlcS-10xFucT-4xFucS-NOTCH3(40-2321) [Golgi membrane]
NOTCH3(1572-2321) [plasma membrane]
14xGlcS-10xFucT-4xFucS-NOTCH3(40-1571) [extracellular region]
14xGlcS-10xFucT-4xFucS-NOTCH3(40-1571) [Golgi membrane]
NOTCH3(1572-2321) [Golgi membrane]
Inferred To
NOTCH1 [plasma membrane] (Gallus gallus)
Notch3 [plasma membrane] (Mus musculus)
Notch3 [plasma membrane] (Rattus norvegicus)
Cross References
RefSeq
Guide to Pharmacology - Targets
OpenTargets
ZINC - Substances
ZINC target
PRO
GlyGen
PDB
GeneCards
HPA
Ensembl
Pharos - Targets
ZINC - Predictions - Purchasable
Orphanet
Interactors (4)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q9UM47 NOTCH3  20 0.558 2
 UniProt:P86480 PR20D      0.556 3
 UniProt:Q9NWT6 HIF1AN  1 0.527 2
 UniProt:Q9R1P4 Psma1  2 0.508 2
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