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CAP1 [extracellular region]
Stable Identifier
R-HSA-350746
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Adenylyl cyclase-associated protein 1
Icon
Locations in the PathwayBrowser
Expand all
Hemostasis (Homo sapiens)
Platelet activation, signaling and aggregation (Homo sapiens)
Response to elevated platelet cytosolic Ca2+ (Homo sapiens)
Platelet degranulation (Homo sapiens)
Release of (inferred) platelet cytosolic components (Homo sapiens)
Platelet releasate (inferred) cytosolic proteins [extracellular region] (Homo sapiens)
CAP1 [extracellular region] (Homo sapiens)
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of azurophil granule lumen proteins (Homo sapiens)
Azurophil granule lumen proteins [extracellular region] (Homo sapiens)
CAP1 [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q01518 CAP1
Gene Names
CAP1, CAP
Chain
initiator methionine:, chain:2-475
Reference Genes
BioGPS Gene:10487 CAP1
COSMIC (genes):CAP1 CAP1
CTD Gene:10487 CAP1
dbSNP Gene:10487 CAP1
ENSEMBL:ENSG00000131236 CAP1
ENSEMBL_homo_sapiens_GENE:ENSG00000131236.18 CAP1
HGNC:20040 CAP1
KEGG Gene (Homo sapiens):10487 CAP1
Monarch:10487 CAP1
NCBI Gene:10487 CAP1
OMIM:617801 CAP1
UCSC:Q01518 CAP1
Reference Transcript
RefSeq:XM_017000067.1 CAP1
RefSeq:XM_011540510.1 CAP1
RefSeq:XM_017000068.1 CAP1
RefSeq:XM_011540511.1 CAP1
RefSeq:NM_001105530.1 CAP1
RefSeq:XM_017000069.1 CAP1
RefSeq:XM_017000070.1 CAP1
RefSeq:XM_011540512.1 CAP1
RefSeq:NM_006367.3 CAP1
RefSeq:XM_017000071.1 CAP1
RefSeq:XM_011540513.2 CAP1
RefSeq:XM_005270368.1 CAP1
RefSeq:XM_017000072.1 CAP1
RefSeq:XM_011540514.1 CAP1
RefSeq:XM_011540515.1 CAP1
RefSeq:XM_011540509.1 CAP1
Other Identifiers
10487
11719377_x_at
11745801_s_at
16662968
200625_PM_s_at
200625_s_at
213798_PM_s_at
213798_s_at
2331728
2331729
2331737
2331738
2331739
2331740
2331741
2331743
2331744
2331745
2331746
2331750
2331752
2331753
2331755
2331757
2331758
2331760
2630486
2630488
2630494
3286367
3286369
7900382
935_at
A_14_P104430
A_24_P62615
A_33_P3281816
GE61261
GO:0000902
GO:0001667
GO:0003779
GO:0005515
GO:0005576
GO:0005615
GO:0005737
GO:0005764
GO:0005773
GO:0005856
GO:0005886
GO:0005925
GO:0006898
GO:0007010
GO:0007015
GO:0007163
GO:0007165
GO:0007190
GO:0008092
GO:0008179
GO:0016020
GO:0016192
GO:0019933
GO:0023052
GO:0030036
GO:0030864
GO:0031410
GO:0035578
GO:0043226
GO:0048856
GO:0048870
GO:0070062
HMNXSV003021654
Hs.104125.2.A1_3p_a_at
ILMN_1797604
ILMN_1880116
L12168_at
PH_hs_0005778
TC01000504.hg
g10938021_3p_a_at
Participates
as a member of
Platelet releasate (inferred) cytosolic proteins [extracellular region] (Homo sapiens)
Azurophil granule lumen proteins [extracellular region] (Homo sapiens)
Other forms of this molecule
CAP1 [cytosol]
CAP1 [azurophil granule lumen]
Inferred To
cas-1 [extracellular region]
(Caenorhabditis elegans)
CAP1 [extracellular region]
(Bos taurus)
CAP1 [extracellular region]
(Canis familiaris)
CAP1 [extracellular region]
(Gallus gallus)
CAP1 [extracellular region]
(Sus scrofa)
capt [extracellular region]
(Drosophila melanogaster)
cap [extracellular region]
(Dictyostelium discoideum)
Cap1 [extracellular region]
(Mus musculus)
Cap1 [extracellular region]
(Rattus norvegicus)
SRV2 [extracellular region]
(Saccharomyces cerevisiae)
cap1 [extracellular region]
(Danio rerio)
cap1 [extracellular region]
(Schizosaccharomyces pombe)
cap1 [extracellular region]
(Xenopus tropicalis)
Cross References
RefSeq
XP_011538813.1
,
NP_001099000.1
,
XP_005270425.1
,
XP_016855556.1
,
XP_016855557.1
,
NP_006358.1
,
XP_011538814.1
,
XP_011538811.1
,
XP_016855558.1
,
XP_011538815.1
,
XP_016855560.1
,
XP_016855559.1
,
XP_011538816.1
,
XP_016855561.1
,
XP_011538817.1
,
XP_011538812.1
OpenTargets
ENSG00000131236
GeneCards
Q01518
HPA
ENSG00000131236-CAP1
Ensembl
ENSP00000361891
,
ENSG00000131236
,
ENST00000372802
,
ENSP00000361883
,
ENST00000372805
,
ENSP00000361888
,
ENST00000372797
,
ENSP00000361884
,
ENST00000340450
,
ENST00000372798
,
ENSP00000344832
,
ENSP00000361878
,
ENST00000372792
PRO
Q01518
Pharos - Targets
Q01518
PDB
1K8F
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P13569 CFTR
17
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.725
14
UniProt:P0DTC3 3a
9
O-glycosyl 3a [virion membrane]
(R-COV-9694395)
O-glycosyl 3a [endocytic vesicle membrane]
(R-COV-9694729)
O-glycosyl 3a [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-COV-9694386)
GalNAc-O-3a [endoplasmic reticulum-Golgi intermediate compartment]
(R-COV-9694658)
3a [endoplasmic reticulum-Golgi intermediate compartment]
(R-COV-9694716)
3a [endoplasmic reticulum lumen]
(R-COV-9694584)
O-glycosyl 3a [endolysosome membrane]
(R-COV-9754541)
O-glycosyl 3a [plasma membrane]
(R-COV-9694433)
O-glycosyl 3a [extracellular region]
(R-COV-9694387)
0.613
3
UniProt:P60709 ACTB
5
Unfolded ACTB [cytosol]
(R-HSA-390462)
ACTB [nucleoplasm]
(R-HSA-3321990)
ACTB [cytosol]
(R-HSA-201861)
ACTB [lysosomal membrane]
(R-HSA-196160)
ACTB [plasma membrane]
(R-HSA-196016)
0.527
4
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