Reactome | PHF1 [nucleoplasm]

PHF1 [nucleoplasm]

Stable Identifier

R-HSA-5084105

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

PHD finger protein 1, PHF1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O43189 PHF1

Gene Names

PHF1, PCL1

Chain

chain:1-567

Reference Genes

BioGPS Gene:5252 PHF1

COSMIC (genes):PHF1 PHF1

CTD Gene:5252 PHF1

dbSNP Gene:5252 PHF1

ENSEMBL:ENSG00000112511 PHF1

ENSEMBL_homo_sapiens_GENE:ENSG00000112511.18 PHF1

ENSEMBL_homo_sapiens_GENE:ENSG00000225553.7 PHF1

HGNC:8919 PHF1

KEGG Gene (Homo sapiens):5252 PHF1

Monarch:5252 PHF1

NCBI Gene:5252 PHF1

OMIM:602881 PHF1

UCSC:O43189 PHF1

Reference Transcript

Other Identifiers

11716721_a_at

11716722_a_at

17007475

17038808

17041368

202928_3p_s_at

202928_PM_s_at

202928_s_at

2903674

2903675

2903676

2903680

2903682

2903683

2903684

2903685

2903687

2903688

2903689

2903690

2903691

2903693

2903694

2903695

2903697

2903698

2903699

2903700

2903702

40446_3p_at

40446_PM_at

40446_at

4884570C_3p_s_at

5252

8118682

A_14_P124800

A_23_P156732

GE79617

GO:0001222

GO:0003677

GO:0003682

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0005737

GO:0005813

GO:0005815

GO:0005829

GO:0005856

GO:0006325

GO:0006351

GO:0006355

GO:0006974

GO:0035064

GO:0035098

GO:0035861

GO:0042393

GO:0042802

GO:0043226

GO:0046872

GO:0140861

GO:1990226

HMNXSV003049396

ILMN_1746968

ILMN_1752877

ILMN_2385866

PH_hs_0010012

TC06000423.hg

TC06002739.hg

TC6_qbl_hap6000103.hg

TC6_ssto_hap7000092.hg

g13435396_3p_a_at

g13435396_3p_s_at

g13435396_3p_x_at

Participates

as a component of

PRC2:PHF1 [nucleoplasm] (Homo sapiens)

Inferred To

PHF1 [nucleoplasm] (Bos taurus)

PHF1 [nucleoplasm] (Canis familiaris)

PHF1 [nucleoplasm] (Sus scrofa)

Phf1 [nucleoplasm] (Mus musculus)

Phf1 [nucleoplasm] (Rattus norvegicus)

Ghost homologue of PHF1 [nucleoplasm] (Danio rerio)

Ghost homologue of PHF1 [nucleoplasm] (Drosophila melanogaster)

phf1 [nucleoplasm] (Xenopus tropicalis)

ceh-91 [nucleoplasm] (Caenorhabditis elegans)

Cross References

RefSeq

NP_077084.1, XP_011512964.1, NP_002627.1

OpenTargets

ENSG00000112511

HPA

ENSG00000112511-PHF1

GeneCards

O43189

Ensembl

ENST00000427869, ENST00000454914, ENSG00000112511, ENSP00000363636, ENSP00000391901, ENSP00000363640, ENST00000374512, ENSP00000407295, ENST00000374516, ENSG00000225553

PRO

O43189

Pharos - Targets

O43189

PDB

5XFO, 2E5P, 7LKY, 6WAT, 4HCZ, 2M0O, 5XFP, 5XFN, 6WAV

Interactors (13)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q15910 EZH2	1	EZH2 [nucleoplasm] (R-HSA-212298)	0.854	7
UniProt:Q15742 NAB2	1	NAB2 [nucleoplasm] (R-HSA-9612177)	0.781	7
UniProt:Q96CA5 BIRC7	1	BIRC7 [cytosol] (R-HSA-50855)	0.666	4
UniProt:O75530 EED	1	EED [nucleoplasm] (R-HSA-212278)	0.643	4
UniProt:Q15022 SUZ12	2	SUZ12 [nucleoplasm] (R-HSA-212217) monoSUMO1-K75-SUZ12 [nucleoplasm] (R-HSA-4615932)	0.643	4
UniProt:Q9Y5V3 MAGED1	1	MAGED1 [cytosol] (R-HSA-196002)	0.556	3
UniProt:Q9UBB9 TFIP11	1	TFIP11 [nucleoplasm] (R-HSA-8869310)	0.556	3
UniProt:Q14192 FHL2	1	FHL2 [nucleoplasm] (R-HSA-561161)	0.556	3
UniProt:O14503 BHLHE40	1	BHLHE40 [nucleoplasm] (R-HSA-879741)	0.556	3
UniProt:Q9UGI0 ZRANB1	1	ZRANB1 [cytosol] (R-HSA-6781939)	0.556	3
UniProt:Q92917 GPKOW	1	GPKOW [nucleoplasm] (R-HSA-8850839)	0.556	3
UniProt:Q09028 RBBP4	1	RBBP4 [nucleoplasm] (R-HSA-212223)	0.527	2
UniProt:Q16576 RBBP7	1	RBBP7 [nucleoplasm] (R-HSA-212227)	0.527	2