Reactome | MED19 [nucleoplasm]

MED19 [nucleoplasm]

Stable Identifier

R-HSA-556819

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Mediator of RNA polymerase II transcription subunit 19, MED19_HUMAN

Locations in the PathwayBrowser

Expand all

Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Viral Infection Pathways (Homo sapiens)
    - Respiratory Syncytial Virus Infection Pathway (Homo sapiens)
      - RSV-host interactions (Homo sapiens)
        
        NS1 (1C) binds to Mediator complex (Homo sapiens)
        
        Mediator Complex (consensus) [nucleoplasm] (Homo sapiens)
        
        MED19 [nucleoplasm] (Homo sapiens)
        
        Mediator:NS1 [nucleoplasm] (Homo sapiens)
        
        Mediator Complex (consensus) [nucleoplasm] (Homo sapiens)
        
        MED19 [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:A0JLT2 MED19

Gene Names

MED19, LCMR1

Chain

chain:1-244

Reference Genes

COSMIC (genes):MED19 MED19

dbSNP Gene:219541 MED19

ENSEMBL:ENSG00000156603 MED19

Participates

as a component of

Mediator Complex (consensus) [nucleoplasm] (Homo sapiens)

Interactors (27)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9BTT4 MED10	1	MED10 [nucleoplasm] (R-HSA-212410)	0.911	12
UniProt:Q9NPJ6 MED4	1	MED4 [nucleoplasm] (R-HSA-350263)	0.886	11
UniProt:P49336 CDK8	1	CDK8 [nucleoplasm] (R-HSA-212440)	0.848	10
UniProt:Q9NVC6 MED17	1	MED17 [nucleoplasm] (R-HSA-212401)	0.837	8
UniProt:Q15648 MED1	1	MED1 [nucleoplasm] (R-HSA-212445)	0.837	7
UniProt:Q9H944 MED20	1	MED20 [nucleoplasm] (R-HSA-212428)	0.837	8
UniProt:O43513 MED7	1	MED7 [nucleoplasm] (R-HSA-212430)	0.837	7
UniProt:Q9Y3C7 MED31	1	MED31 [nucleoplasm] (R-HSA-212429)	0.837	8
UniProt:Q96HR3 MED30	1	MED30 [nucleoplasm] (R-HSA-212398)	0.788	6
UniProt:Q93074 MED12	1	MED12 [nucleoplasm] (R-HSA-212343)	0.788	6
UniProt:Q71SY5 MED25	1	MED25 [nucleoplasm] (R-HSA-212414)	0.788	6
UniProt:Q96G25 MED8	1	MED8 [nucleoplasm] (R-HSA-556784)	0.788	7
UniProt:O75586 MED6	1	MED6 [nucleoplasm] (R-HSA-212359)	0.788	7
UniProt:O60244 MED14	1	MED14 [nucleoplasm] (R-HSA-212441)	0.788	7
UniProt:Q9UHV7 MED13	1	MED13 [nucleoplasm] (R-HSA-212391)	0.788	6
UniProt:Q9Y2X0 MED16	1	MED16 [nucleoplasm] (R-HSA-556802)	0.788	6
UniProt:Q6P2C8 MED27	1	MED27 [nucleoplasm] (R-HSA-556761)	0.788	6
UniProt:Q9ULK4 MED23	1	MED23 [nucleoplasm] (R-HSA-556823)	0.774	6
UniProt:O95402 MED26	1	MED26 [nucleoplasm] (R-HSA-556783)	0.725	8
UniProt:Q96RN5 MED15	1	MED15 [nucleoplasm] (R-HSA-556827)	0.725	5
UniProt:O75448 MED24	1	MED24 [nucleoplasm] (R-HSA-212331)	0.725	5
UniProt:P19388 POLR2E	2	POLR2E [cytosol] (R-HSA-1964438) POLR2E [nucleoplasm] (R-HSA-83713)	0.725	4
UniProt:P24863 CCNC	1	CCNC [nucleoplasm] (R-HSA-212418)	0.643	4
UniProt:P61218 POLR2F	2	POLR2F [cytosol] (R-HSA-1964441) POLR2F [nucleoplasm] (R-HSA-83714)	0.527	2
UniProt:P62875 POLR2L	2	POLR2L [cytosol] (R-HSA-1964467) POLR2L [nucleoplasm] (R-HSA-83715)	0.527	2
UniProt:P52434 POLR2H	2	POLR2H [cytosol] (R-HSA-1964450) POLR2H [nucleoplasm] (R-HSA-63523)	0.527	2
UniProt:Q9NR30 DDX21	1	DDX21 [nucleoplasm] (R-HSA-5250652)	0.483	2