MED1 [nucleoplasm]

Stable Identifier
R-HSA-212445
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
TRAP220, PBP
Locations in the PathwayBrowser
Expand all
General
MED1 is a component of each of the various Mediator complexes, that function as transcription co-activators. The MED1-containing compolexes include the DRIP, ARC, TRIP and CRSP compllexes.
External Reference Information
External Reference
UniProt:Q15648 MED1
Gene Names
MED1, ARC205, CRSP1, CRSP200, DRIP205, DRIP230, PBP, PPARBP, PPARGBP, RB18A, TRAP220, TRIP2
Chain
chain:1-1581
Reference Genes
BioGPS Gene:5469 MED1
COSMIC (genes):MED1 MED1
CTD Gene:5469 MED1
dbSNP Gene:5469 MED1
ENSEMBL:ENSG00000125686 MED1
HGNC:9234 MED1
KEGG:hsa:5469 MED1
Monarch:5469 MED1
NCBI Gene:5469 MED1
OMIM:604311 MED1
UCSC:Q15648 MED1
Reference Transcript
Other Identifiers
11721007_a_at
11721008_a_at
11721009_at
16844155
203496_PM_s_at
203496_s_at
203497_PM_at
203497_at
225452_PM_at
225452_at
225456_PM_at
225456_at
32064_at
3755697
3755698
3755699
3755700
3755701
3755702
3755716
3755717
3755718
3755719
3755720
3755721
3755722
3755723
3755724
3755725
3755727
3755728
3755729
3755730
3755731
3755732
3755733
3755734
3755735
3755736
3755737
3755738
3755740
3755741
3755742
3755743
3755744
3755745
3755748
3755749
3755750
44549_at
5469
56136_at
8014841
A_23_P15314
A_23_P425704
A_24_P940666
A_33_P3210423
GE86426
GO:0000122
GO:0000151
GO:0000785
GO:0000902
GO:0000978
GO:0001223
GO:0001525
GO:0001701
GO:0001889
GO:0001892
GO:0002088
GO:0002154
GO:0003222
GO:0003406
GO:0003677
GO:0003682
GO:0003712
GO:0003713
GO:0003714
GO:0003824
GO:0005515
GO:0005634
GO:0005654
GO:0005730
GO:0006351
GO:0006355
GO:0006357
GO:0006575
GO:0006590
GO:0006606
GO:0006629
GO:0006702
GO:0006886
GO:0006913
GO:0007420
GO:0007507
GO:0007595
GO:0008284
GO:0009887
GO:0010628
GO:0010839
GO:0016020
GO:0016071
GO:0016567
GO:0016592
GO:0016740
GO:0016922
GO:0022414
GO:0030154
GO:0030216
GO:0030224
GO:0030331
GO:0030374
GO:0030518
GO:0031100
GO:0031490
GO:0032968
GO:0032993
GO:0033148
GO:0033598
GO:0035035
GO:0035050
GO:0035116
GO:0035162
GO:0035357
GO:0035729
GO:0035855
GO:0042789
GO:0042809
GO:0042974
GO:0042975
GO:0043010
GO:0043066
GO:0043226
GO:0044877
GO:0045023
GO:0045444
GO:0045618
GO:0045648
GO:0045665
GO:0045893
GO:0045944
GO:0046966
GO:0048821
GO:0048822
GO:0048856
GO:0050693
GO:0051123
GO:0060090
GO:0060218
GO:0060261
GO:0060335
GO:0060744
GO:0060745
GO:0060750
GO:0061629
GO:0061630
GO:0065003
GO:0070318
GO:0070562
GO:0070847
GO:0071364
GO:0071383
GO:0097067
GO:0140096
GO:0140110
GO:0140296
GO:0140297
GO:1990841
GO:2000347
GO:2001141
HMNXSV003029846
HMNXSV003047175
Hs.10130.0.A1_3p_at
Hs.10130.0.A2_3p_at
ILMN_1721729
L40366_at
PH_hs_0001448
TC17001449.hg
TC17002613.hg
g3319289_3p_a_at
g4759265_3p_at
Participates
as a component of
as an input of
as a member of
Inferred To
Ghost homologue of MED1 [nucleoplasm] (Danio rerio)
MED1 [nucleoplasm] (Bos taurus)
MED1 [nucleoplasm] (Canis familiaris)
MED1 [nucleoplasm] (Dictyostelium discoideum)
MED1 [nucleoplasm] (Drosophila melanogaster)
MED1 [nucleoplasm] (Gallus gallus)
MED1 [nucleoplasm] (Sus scrofa)
med1l [nucleoplasm] (Xenopus tropicalis)
Med1 [nucleoplasm] (Mus musculus)
Med1 [nucleoplasm] (Rattus norvegicus)
Cross References
RefSeq
OpenTargets
ENSEMBL
HPA
PRO
Pharos - Targets
GlyGen
PDB
Interactors (45)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P49336 CDK8  1 0.915 17
 UniProt:Q9BTT4 MED10  1 0.901 9
 UniProt:Q9NWA0 MED9  1 0.837 9
 UniProt:A0JLT2 MED19  1 0.837 7
 UniProt:P10276 RARA  3 0.818 6
 UniProt:Q13503 MED21  1 0.802 7
 UniProt:Q9NPJ6 MED4  1 0.802 9
 UniProt:Q9NX70 MED29  1 0.788 7
 UniProt:O95402 MED26  1 0.788 13
 UniProt:O43513 MED7  1 0.773 8
 UniProt:Q9BWU1 CDK19  1 0.744 6
 UniProt:P11473 VDR  2 0.743 4
 UniProt:Q9Y3C7 MED31  1 0.725 5
 UniProt:Q9H944 MED20  1 0.725 5
 UniProt:O60244 MED14  1 0.725 5
 UniProt:O75448 MED24  1 0.725 5
 UniProt:Q9NVC6 MED17  1 0.725 5
 UniProt:Q9BUE0 MED18  1 0.725 6
 UniProt:P19793 RXRA  4 0.697 6
 UniProt:Q9UHV7 MED13  1 0.643 5
 UniProt:O75586 MED6  1 0.643 4
 UniProt:Q71SY5 MED25  1 0.643 4
 UniProt:Q96HR3 MED30  1 0.643 4
 UniProt:Q9P086 MED11  1 0.643 4
 UniProt:Q71F56 MED13L  1 0.643 5
 UniProt:Q9H204 MED28  1 0.643 4
 UniProt:Q93074 MED12  1 0.643 5
 UniProt:Q9ULK4 MED23  1 0.615 4
 UniProt:P10827 THRA  1 0.591 4
 UniProt:P15976 GATA1  1 0.582 6
 UniProt:P03372 ESR1  10 0.564 3
 UniProt:Q6P2C8 MED27  1 0.527 3
 UniProt:Q9Y2X0 MED16  1 0.527 3
 UniProt:P24863 CCNC  1 0.527 3
 UniProt:Q96G25 MED8  1 0.527 3
 UniProt:Q96RN5 MED15  1 0.527 4
 UniProt:O15514 POLR2D  1 0.527 2
 UniProt:Q8IXW5 RPAP2  1 0.527 2
 UniProt:O95988 TCL1B      0.527 2
 UniProt:Q00987 MDM2  11 0.524 3
 UniProt:P04637 TP53  20 0.524 3
 UniProt:P53350 PLK1  4 0.508 2
 UniProt:Q96R06 SPAG5      0.508 2
 UniProt:P10275 AR  4 0.471 2
 UniProt:Q92731 ESR2  5 0.462 2
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