Reactome | PTRF [nucleoplasm]

PTRF [nucleoplasm]

Stable Identifier

R-HSA-74981

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Leucine-zipper protein FKSG13

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q6NZI2 PTRF

Gene Names

PTRF, FKSG13, CAVIN1

Chain

chain:1-390

Reference Genes

BioGPS Gene:284119 PTRF

CTD Gene:284119 PTRF

dbSNP Gene:284119 PTRF

ENSEMBL:ENSG00000177469 PTRF

ENSEMBL_homo_sapiens_GENE:ENSG00000177469.13 PTRF

HGNC:9688 PTRF

KEGG Gene (Homo sapiens):284119 PTRF

Monarch:284119 PTRF

NCBI Gene:284119 PTRF

OMIM:603198 PTRF

UCSC:Q6NZI2 PTRF

Reference Transcript

RefSeq:NM_012232.5 PTRF

Other Identifiers

11730730_s_at

11745377_x_at

11749223_a_at

1557938_PM_s_at

1557938_s_at

16845158

208789_PM_at

208789_at

208790_PM_s_at

208790_s_at

284119

34320_at

36369_at

3757918

3757919

3757920

3757921

3757922

3757923

3757930

3757931

3757932

8015635

A_23_P141376

A_23_P394064

A_33_P3280066

GE516754

GO:0003723

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0005739

GO:0005783

GO:0005829

GO:0005886

GO:0005901

GO:0006351

GO:0006353

GO:0006361

GO:0006363

GO:0009303

GO:0009306

GO:0016020

GO:0019843

GO:0032991

GO:0042134

GO:0042802

GO:0043226

GO:0043231

GO:0045121

GO:0048870

GO:2000147

HMNXSV003040757

Hs.29759.0.S2_3p_at

Hs.29759.0.S2_3p_s_at

Hs2.406061.1.S1_3p_s_at

ILMN_1757552

PH_hs_0028546

TC17001532.hg

g11034808_3p_s_at

Participates

as an output of

Dissociation of PTRF:Polymerase I/Nascent Pre rRNA Complex:TTF-I:Sal Box (Homo sapiens)

as a component of

PTRF:Polymerase I/Nascent Pre rRNA Complex:TTF-I:Sal Box [nucleoplasm] (Homo sapiens)

as an input of

PTRF Binds the Polymerase I Transcription Complex/Nascent Pre rRNA Complex paused at the TTF-I:Sal Box (Homo sapiens)

Other forms of this molecule

CAVIN1 [plasma membrane]

Inferred To

CAVIN1 [nucleoplasm] (Bos taurus)

CAVIN1 [nucleoplasm] (Canis familiaris)

CAVIN1 [nucleoplasm] (Sus scrofa)

Cavin1 [nucleoplasm] (Mus musculus)

Cavin1 [nucleoplasm] (Rattus norvegicus)

cavin1b [nucleoplasm] (Danio rerio)

cavin1 [nucleoplasm] (Xenopus tropicalis)

PTRF [nucleoplasm] (Gallus gallus)

Ghost homologue of PTRF [nucleoplasm] (Caenorhabditis elegans)

Cross References

RefSeq

NP_036364.2

GeneCards

Q6NZI2

HPA

ENSG00000177469-CAVIN1

Ensembl

ENSG00000177469, ENST00000357037, ENSP00000349541

PRO

Q6NZI2

Pharos - Targets

Q6NZI2

Orphanet

19044

Interactors (36)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q969G5 CAVN3			0.77	12
UniProt:Q9NVF7 FBX28			0.742	5
UniProt:P0DTC9 N	13	SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [plasma membrane] (R-COV-9729325) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [nucleolus] (R-COV-9729339) N [plasma membrane] (R-COV-9694356) SUMO1-K62,ADPr-,p-11S,2T,met-R95,177,Ac-K375-N [cytosol] (R-COV-9756489) N [cytosol] (R-COV-9694300) p-S188,206-N [cytosol] (R-COV-9729324) p-8S-N [cytosol] (R-COV-9729335) p-8S,2T-N [cytosol] (R-COV-9729277) p-11S,2T-N [cytosol] (R-COV-9729264) p-11S,2T-metR95,177-N [cytosol] (R-COV-9729308) ADPr-p-11S,2T-metR95,177-N [cytosol] (R-COV-9729275) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9729341) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol] (R-COV-9729340)	0.725	5
UniProt:Q6NZI2 PTRF	2	PTRF [nucleoplasm] (R-HSA-74981) CAVIN1 [plasma membrane] (R-HSA-9714278)	0.703	5
UniProt:P56539 CAV3	1	CAV3 [plasma membrane] (R-HSA-1368135)	0.669	4
UniProt:Q5MJ10 SPXN2			0.666	4
UniProt:Q8TBK6 ZCH10			0.666	4
UniProt:Q03135 CAV1	5	CAV1 [Golgi membrane] (R-HSA-204504) CAV1 [plasma membrane] (R-HSA-534994) CAV1 [lipid droplet] (R-HSA-163510) CAV1 [endocytic vesicle membrane] (R-HSA-535009) CAV1 [early endosome membrane] (R-HSA-5368451)	0.641	10
UniProt:Q6P2D0 ZFP1	1	ZFP1 [nucleoplasm] (R-HSA-974997)	0.556	3
UniProt:Q5MJ09 SPXN3			0.556	3
UniProt:Q3SY00 T10IP			0.556	3
UniProt:Q92993 KAT5	1	KAT5 [nucleoplasm] (R-HSA-3321979)	0.556	3
UniProt:Q8IY57-5 YAF2			0.556	3
UniProt:Q16543 CDC37	1	CDC37 [cytosol] (R-HSA-1221609)	0.556	3
UniProt:Q9BRJ2 MRPL45	1	MRPL45 [mitochondrial inner membrane] (R-HSA-5368224)	0.556	3
UniProt:Q5QJE6 TDIF2			0.556	3
UniProt:Q96GN5 CDA7L			0.556	3
UniProt:Q9C086 INO80B	1	INO80B [nucleoplasm] (R-HSA-5689599)	0.556	3
UniProt:Q8N0Z6 TTC5	3	p-S203-TTC5 [nucleoplasm] (R-HSA-6804261) p-S203,S221-TTC5 [nucleoplasm] (R-HSA-6804259) TTC5 [nucleoplasm] (R-HSA-6804264)	0.556	3
UniProt:Q8WVP5 TNFAIP8L1	1	TNFAIP8L1 [cytosol] (R-HSA-8874482)	0.556	3
UniProt:Q9Y5A6 ZSC21			0.556	3
UniProt:P46939 UTRN	1	UTRN [cytosol] (R-HSA-5216039)	0.527	2
UniProt:Q14192 FHL2	1	FHL2 [nucleoplasm] (R-HSA-561161)	0.527	2
UniProt:Q969S3 ZN622			0.527	2
UniProt:Q5T447 HECTD3	1	HECTD3 [cytosol] (R-HSA-975991)	0.527	3
UniProt:O95721 SNAP29	3	SNAP29 [azurophil granule membrane] (R-HSA-6799359) SNAP29 [plasma membrane] (R-HSA-2029020) SNAP29 [Golgi membrane] (R-HSA-6810997)	0.527	2
UniProt:Q15554 TERF2	2	TERF2 [nucleoplasm] (R-HSA-174895) p-S365-TERF2 [nucleoplasm] (R-HSA-9686530)	0.527	2
UniProt:Q9Y6D9 MAD1L1	1	MAD1L1 [cytosol] (R-HSA-141433)	0.527	2
UniProt:Q9UJT2 TSKS			0.527	2
UniProt:P11142 HSPA8	10	Me3K561-HSPA8 [nucleoplasm] (R-HSA-8932217) HSPA8 [secretory granule lumen] (R-HSA-6801530) HSPA8 [extracellular region] (R-HSA-6805936) HSPA8 [ficolin-1-rich granule lumen] (R-HSA-6801494) HSPA8 [nucleoplasm] (R-HSA-5082380) HSPA8 [plasma membrane] (R-HSA-936508) HSPA8 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-HSA-888599) HSPA8 [late endosome lumen] (R-HSA-9631104) HSPA8 [lysosomal lumen] (R-HSA-9625182) HSPA8 [cytosol] (R-HSA-264476)	0.527	2
UniProt:Q8IYB1 M21D2			0.527	2
UniProt:O43149 ZZEF1			0.527	3
UniProt:Q96M94 KLH15			0.527	2
UniProt:Q8IZU1 FAM9A			0.527	2
UniProt:Q9C0C9 UBE2O	1	UBE2O [cytosol] (R-HSA-947641)	0.527	3
UniProt:O95810 CAVN2			0.499	6

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