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DBT [cytosol]
Stable Identifier
R-HSA-9714663
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
RHOH GTPase cycle (Homo sapiens)
RHOH binds effectors at the plasma membrane (Homo sapiens)
RHOH effectors [cytosol] (Homo sapiens)
DBT [cytosol] (Homo sapiens)
RHOH:GTP:RHOH effectors [plasma membrane] (Homo sapiens)
RHOH effectors [cytosol] (Homo sapiens)
DBT [cytosol] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
9773790
Tissue-specific responses of branched-chain alpha-ketoacid dehydrogenase activity in metabolic acidosis
Wang, X
,
Price, SR
,
Bailey, JL
J Am Soc Nephrol
1998
External Reference Information
External Reference
UniProt:P11182 DBT
Gene Names
DBT, BCATE2, BCKDHE2
Chain
transit peptide:1-61, chain:62-482
Reference Genes
BioGPS Gene:1629 DBT
COSMIC (genes):DBT DBT
CTD Gene:1629 DBT
dbSNP Gene:1629 DBT
ENSEMBL:ENSG00000137992 DBT
ENSEMBL_homo_sapiens_GENE:ENSG00000137992.15 DBT
HGNC:2698 DBT
KEGG Gene (Homo sapiens):1629 DBT
Monarch:1629 DBT
NCBI Gene:1629 DBT
OMIM:248610 DBT
UCSC:P11182 DBT
Reference Transcript
RefSeq:NM_001918.3 DBT
Other Identifiers
11731509_x_at
11731510_at
11731511_s_at
11751182_a_at
11752357_a_at
1629
16690103
205369_3p_x_at
205369_PM_x_at
205369_x_at
205370_PM_x_at
205370_x_at
205371_PM_s_at
205371_s_at
231919_PM_at
231919_at
2425203
2425205
2425207
2425209
2425210
2425211
2425213
2425214
2425215
2425216
2425217
2425218
2425219
2425221
2425231
2425233
2425234
2425237
2425238
2425239
2425240
2425242
244687_PM_at
244687_at
51919_at
7918008
86425_at
A_23_P74022
A_24_P28524
A_32_P50005
A_33_P3308949
GE59930
GE85471
GO:0003824
GO:0005515
GO:0005737
GO:0005739
GO:0005759
GO:0005829
GO:0005856
GO:0005947
GO:0006520
GO:0008289
GO:0009083
GO:0015630
GO:0016407
GO:0016740
GO:0016746
GO:0019752
GO:0031405
GO:0031625
GO:0042645
GO:0043226
GO:0043754
GO:1990204
HMNXSV003008442
Hs.199210.0.A1_3p_at
Hs.257043.0.S1_3p_at
ILMN_1714990
ILMN_1887403
M27093_s_at
PH_hs_0013509
PH_hs_0021360
PH_hs_0027858
TC01002918.hg
X66785_at
g179353_3p_a_at
g179353_3p_x_at
g186635_3p_a_at
g4503264_3p_at
g736674_3p_a_at
Participates
as a candidate of
RHOH effectors [cytosol] (Homo sapiens)
Other forms of this molecule
DBT [mitochondrial matrix]
Lipo-K105-DBT [mitochondrial matrix]
Inferred To
dbt [cytosol]
(Xenopus tropicalis)
Dbt [cytosol]
(Rattus norvegicus)
bkdC [cytosol]
(Dictyostelium discoideum)
Dbct [cytosol]
(Drosophila melanogaster)
DBT [cytosol]
(Bos taurus)
DBT [cytosol]
(Caenorhabditis elegans)
DBT [cytosol]
(Canis familiaris)
DBT [cytosol]
(Gallus gallus)
DBT [cytosol]
(Mus musculus)
DBT [cytosol]
(Sus scrofa)
Cross References
RefSeq
NP_001909.3
OpenTargets
ENSG00000137992
HPA
ENSG00000137992-DBT
GeneCards
P11182
Ensembl
ENST00000370132
,
ENSG00000137992
,
ENSP00000359151
PRO
P11182
Pharos - Targets
P11182
Orphanet
15851
HMDB Protein
HMDBP03078
PDB
1K8O
,
3RNM
,
1ZWV
,
1K8M
,
2COO
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