Reactome | NOL12 [nucleoplasm]

NOL12 [nucleoplasm]

Stable Identifier

R-HSA-6791195

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Nucleolar protein 12, NOL12_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9UGY1 NOL12

Gene Names

NOL12

Chain

chain:1-213

Reference Genes

BioGPS Gene:79159 NOL12

COSMIC (genes):NOL12 NOL12

CTD Gene:79159 NOL12

dbSNP Gene:79159 NOL12

ENSEMBL:ENSG00000273899 NOL12

ENSEMBL_homo_sapiens_GENE:ENSG00000273899.5 NOL12

HGNC:28585 NOL12

KEGG Gene (Homo sapiens):79159 NOL12

Monarch:79159 NOL12

NCBI Gene:79159 NOL12

UCSC:Q9UGY1 NOL12

Reference Transcript

RefSeq:NM_024313.2 NOL12

Other Identifiers

11725338_a_at

11725339_at

11757528_x_at

16929866

219324_PM_at

219324_at

222057_PM_at

222057_at

3944905

3944906

3944910

3944911

3944912

3944913

3944914

3944915

3944916

3944917

3944918

3944919

3944920

3944921

61366_at

79159

8072883

A_23_P6456

A_33_P3417820

GE86321

GE86523

GO:0003677

GO:0003697

GO:0003723

GO:0005515

GO:0005634

GO:0005730

GO:0019843

GO:0042802

GO:0043226

HMNXSV003046085

Hs.326372.1.S1_3p_a_at

Hs.326372.1.S1_3p_at

ILMN_2151368

PH_hs_0016183

TC22001466.hg

g13236552_3p_x_at

This entity regulates

Positively

45S pre-rRNA is nucleolytically processed at site 2 (site 2b) to yield 30S pre-rRNA and 32S pre-rRNA (Homo sapiens)

Cross References

RefSeq

NP_077289.1

OpenTargets

ENSG00000273899

HPA

ENSG00000273899-NOL12

GeneCards

Q9UGY1

Ensembl

ENST00000611699, ENST00000438329, ENSG00000273899, ENSP00000403059, ENSP00000352021, ENST00000359114, ENSP00000482349

PRO

Q9UGY1

Pharos - Targets

Q9UGY1

Interactors (32)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8NHQ1 CEP70	1	CEP70 [cytosol] (R-HSA-380257)	0.666	4
UniProt:P23508 CRCM			0.556	3
UniProt:Q92997 DVL3	4	pp-DVL3 [cytosol] (R-HSA-3772400) p-DVL3 [cytosol] (R-HSA-201680) DVL3 [cytosol] (R-HSA-201678) ub-DVL3 [cytosol] (R-HSA-4652688)	0.556	3
UniProt:P60371 KRTAP10-6	1	KRTAP10-6 [cytosol] (R-HSA-6810247)	0.556	3
UniProt:Q9Y2D8 ADIP			0.556	3
UniProt:Q5MJ10 SPXN2			0.556	3
UniProt:P60409 KRTAP10-7	1	KRTAP10-7 [cytosol] (R-HSA-6810279)	0.556	3
UniProt:Q9H2G4 TSPYL2	1	TSPYL2 [nucleoplasm] (R-HSA-535540)	0.556	3
UniProt:Q96GN5 CDA7L			0.556	3
UniProt:Q9UGY1 NOL12	1	NOL12 [nucleoplasm] (R-HSA-6791195)	0.556	3
UniProt:Q8N7W2-2 BEND7			0.556	3
UniProt:Q8N3Z6 ZCHC7			0.527	2
UniProt:Q8NHQ9 DDX55			0.527	2
UniProt:Q9Y4C8 RBM19			0.527	2
UniProt:Q9NY65 TUBA8	6	AcK-TUBA8 [cytosol] (R-HSA-6805239) TUBA8 folding intermediate [cytosol] (R-HSA-6809339) TUBA8 unfolded [cytosol] (R-HSA-6809333) L-isoglutamyl polyglycyl-TUBA8 [cytosol] (R-HSA-8867462) Polyglutamyl-TUBA8 [cytosol] (R-HSA-8867468) TUBA8 [cytosol] (R-HSA-6805238)	0.527	2
UniProt:Q96K58 ZNF668	1	ZNF668 [nucleoplasm] (R-HSA-2248872)	0.527	3
UniProt:O43159 RRP8	1	RRP8 [nucleoplasm] (R-HSA-427524)	0.527	2
UniProt:Q96CS4 ZNF689	1	ZNF689 [nucleoplasm] (R-HSA-2248889)	0.527	2
UniProt:Q9BRD0 BUD13	1	BUD13 [nucleoplasm] (R-HSA-9769522)	0.527	2
UniProt:Q96QD9 FYTTD1	1	FYTTD1 [nucleoplasm] (R-HSA-8852176)	0.527	2
UniProt:P82933 MRPS9	1	MRPS9 [mitochondrial inner membrane] (R-HSA-5368194)	0.527	2
UniProt:Q9C0C9 UBE2O	1	UBE2O [cytosol] (R-HSA-947641)	0.527	2
UniProt:Q8IY81 FTSJ3	1	FTSJ3 [nucleoplasm] (R-HSA-6791507)	0.527	2
UniProt:Q96GQ7 DDX27			0.527	2
UniProt:Q6PK04 CC137			0.527	2
UniProt:Q02539 H1-1	1	HIST1H1A [nucleoplasm] (R-HSA-211245)	0.527	2
UniProt:Q15397 PUM3			0.527	2
UniProt:Q6P158 DHX57			0.527	2
UniProt:Q8WXF0 SRSF12	1	SRSF12 [nucleoplasm] (R-HSA-9770127)	0.527	2
UniProt:P54274 TERF1	1	TERF1 [nucleoplasm] (R-HSA-164618)	0.508	2
UniProt:P62753 RPS6	4	RPS6 [nucleoplasm] (R-HSA-6790606) 3OHR147-RPS6 [cytosol] (R-HSA-9629876) p-5S-RPS6 [cytosol] (R-HSA-165727) RPS6 [cytosol] (R-HSA-72381)	0.483	3
UniProt:P04591-PRO_0000038596 GAG			0.462	2

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