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XAF1 [cytosol]
Stable Identifier
R-HSA-1015680
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
XIAP-associated factor 1, XAF1_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Interferon Signaling (Homo sapiens)
Interferon alpha/beta signaling (Homo sapiens)
Expression of IFN-induced genes (Homo sapiens)
XAF1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q6GPH4 XAF1
Gene Names
XAF1, BIRC4BP, XIAPAF1
Chain
chain:1-301
Reference Genes
BioGPS Gene:54739 XAF1
COSMIC (genes):XAF1 XAF1
CTD Gene:54739 XAF1
dbSNP Gene:54739 XAF1
ENSEMBL:ENSG00000132530 XAF1
ENSEMBL_homo_sapiens_GENE:ENSG00000132530.17 XAF1
HGNC:30932 XAF1
KEGG Gene (Homo sapiens):54739 XAF1
Monarch:54739 XAF1
NCBI Gene:54739 XAF1
OMIM:606717 XAF1
UCSC:Q6GPH4 XAF1
Reference Transcript
RefSeq:NM_017523.3 XAF1
RefSeq:XM_005256708.2 XAF1
RefSeq:NM_199139.2 XAF1
Other Identifiers
11726769_a_at
11726770_x_at
11726771_a_at
11741202_x_at
11747630_a_at
11747631_x_at
11749370_x_at
16830202
206133_PM_at
206133_at
228617_PM_at
228617_at
35583_at
3708075
3708076
3708079
3708080
3708084
3708086
3708090
3708092
3708093
3708095
3708096
3708098
3708100
54739
60017_at
8004184
A_14_P138656
A_23_P4283
A_23_P4286
A_24_P557479
A_33_P3258346
GE60220
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005739
GO:0005829
GO:0006915
GO:0008270
GO:0012501
GO:0032480
GO:0035456
GO:0043226
GO:0046872
GO:0140313
HMNXSV003016898
HMNXSV003023628
HMNXSV003049166
HMNXSV003058345
Hs.154993.0.A1_3p_at
Hs.154993.0.A1_3p_x_at
ILMN_1742618
ILMN_2370573
PH_hs_0021103
X99699_at
g8923794_3p_at
Participates
as an output of
Expression of IFN-induced genes (Homo sapiens)
Cross References
RefSeq
NP_954590.1
,
NP_059993.2
,
XP_005256765.1
OpenTargets
ENSG00000132530
HPA
ENSG00000132530-XAF1
GeneCards
Q6GPH4
Ensembl
ENSP00000341029
,
ENSP00000458229
,
ENSP00000354822
,
ENST00000574962
,
ENST00000346752
,
ENSG00000132530
,
ENST00000571673
,
ENST00000361842
,
ENSP00000461196
PRO
Q6GPH4
Pharos - Targets
Q6GPH4
PDB
2LXW
Interactors (14)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q96A37 RN166
0.666
4
UniProt:Q9Y508 RNF114
1
RNF114 [cytosol]
(R-HSA-8850894)
0.666
8
UniProt:P31749 AKT1
14
p-T308,S473-AKT1 E17K [nucleoplasm]
(R-HSA-2399994)
p-T308,S473-AKT1 E17K [cytosol]
(R-HSA-2243935)
AKT1 E17K [cytosol]
(R-HSA-2219526)
p-S473-AKT1 E17K [plasma membrane]
(R-HSA-2243944)
AKT1 E17K [plasma membrane]
(R-HSA-1500573)
p-S473-AKT1 [cytosol]
(R-HSA-9841264)
p-T308,S473-AKT1 [plasma membrane]
(R-HSA-199430)
p-Y315,Y326-AKT1 [cytosol]
(R-HSA-8848757)
p-T308-AKT1 [cytosol]
(R-HSA-198634)
AKT1 [cytosol]
(R-HSA-58252)
AKT1 [plasma membrane]
(R-HSA-199416)
p-S473-AKT1 [plasma membrane]
(R-HSA-377265)
p-T308,S473-AKT1 [cytosol]
(R-HSA-198356)
p-T308,S473-AKT1 [nucleoplasm]
(R-HSA-198357)
0.666
4
UniProt:P55072 VCP
8
Me3K315-VCP [cytosol]
(R-HSA-8932209)
VCP [endoplasmic reticulum membrane]
(R-HSA-8943105)
VCP [nucleoplasm]
(R-HSA-5643745)
VCP [secretory granule lumen]
(R-HSA-6801039)
VCP [ficolin-1-rich granule lumen]
(R-HSA-6800425)
VCP [extracellular region]
(R-HSA-6806191)
VCP [azurophil granule lumen]
(R-HSA-6800438)
VCP [cytosol]
(R-HSA-1181251)
0.556
3
UniProt:Q6UWE0 LRSAM1
1
LRSAM1 [cytosol]
(R-HSA-976004)
0.556
3
UniProt:Q96CA5 BIRC7
1
BIRC7 [cytosol]
(R-HSA-50855)
0.556
3
UniProt:P40937 RFC5
1
RFC5 [nucleoplasm]
(R-HSA-68427)
0.556
3
UniProt:P49903 SPS1
0.556
3
UniProt:P19474 TRIM21
1
TRIM21 [cytosol]
(R-HSA-976051)
0.556
3
UniProt:Q14CS0 UBX2B
0.556
3
UniProt:Q86XT4 TRIM50
1
TRIM50 [cytosol]
(R-HSA-5688976)
0.556
3
UniProt:Q9BYV2 TRI54
0.556
6
UniProt:Q8N7C3 TRIMM
0.556
3
UniProt:Q9UI32 GLS2
1
GLS2 [mitochondrial matrix]
(R-HSA-70610)
0.556
3
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