TRIM21 [cytosol]

Stable Identifier
R-HSA-976051
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
E3 ubiquitin-protein ligase TRIM21, RO52_HUMAN
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:P19474 TRIM21
Gene Names
TRIM21, RNF81, RO52, SSA1
Chain
chain:1-475
Reference Genes
BioGPS Gene:6737 TRIM21
COSMIC (genes):TRIM21 TRIM21
CTD Gene:6737 TRIM21
dbSNP Gene:6737 TRIM21
ENSEMBL:ENSG00000132109 TRIM21
HGNC:11312 TRIM21
KEGG:hsa:6737 TRIM21
Monarch:6737 TRIM21
NCBI Gene:6737 TRIM21
OMIM:109092 TRIM21
UCSC:P19474 TRIM21
Reference Transcript
Other Identifiers
11723623_s_at
16734762
204804_PM_at
204804_at
3360143
3360144
3360145
3360146
3360147
3360149
3360150
3360151
3360154
3360156
3360157
3360158
3360159
3360161
37126_at
6737
7945962
A_23_P47691
GE58017
GO:0000209
GO:0000932
GO:0002376
GO:0003677
GO:0003713
GO:0003723
GO:0003824
GO:0004842
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005773
GO:0005776
GO:0005829
GO:0006355
GO:0006513
GO:0008270
GO:0010494
GO:0010498
GO:0010508
GO:0012501
GO:0016567
GO:0016740
GO:0019005
GO:0019901
GO:0030163
GO:0031410
GO:0031648
GO:0032088
GO:0032092
GO:0032479
GO:0032880
GO:0032897
GO:0034341
GO:0035617
GO:0042802
GO:0042803
GO:0043123
GO:0043226
GO:0044314
GO:0044790
GO:0045087
GO:0045787
GO:0045824
GO:0045893
GO:0046596
GO:0046598
GO:0046872
GO:0051091
GO:0051865
GO:0060090
GO:0061630
GO:0062197
GO:0070269
GO:0070534
GO:0070936
GO:0085020
GO:0090086
GO:0098542
GO:0140096
GO:0140110
GO:1990904
HMNXSV003009189
ILMN_1678054
M62800_at
PH_hs_0000135
TC11001309.hg
g4507226_3p_at
Participates
as a component of
as an input of
as a member of
This entity regulates
Negatively
Inferred To
LOC100485429 [cytosol] (Xenopus tropicalis)
trim108 [cytosol] (Danio rerio)
Trim21 [cytosol] (Rattus norvegicus)
trim109 [cytosol] (Danio rerio)
TRIM21 [cytosol] (Bos taurus)
TRIM21 [cytosol] (Caenorhabditis elegans)
TRIM21 [cytosol] (Canis familiaris)
TRIM21 [cytosol] (Gallus gallus)
TRIM21 [cytosol] (Mus musculus)
TRIM21 [cytosol] (Sus scrofa)
Homologues of TRIM21 [cytosol] (Danio rerio)
Homologues of TRIM21 [cytosol] (Gallus gallus)
Cross References
RefSeq
Guide to Pharmacology - Targets
OpenTargets
ENSEMBL
HPA
PRO
Pharos - Targets
GlyGen
PDB
Interactors (36)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P19474 TRIM21  1 0.806 8
 UniProt:Q13588 GRAP  1 0.718 8
 UniProt:Q7KZS0 Q7KZS0      0.718 6
 UniProt:Q99757 TXN2  2 0.718 6
 UniProt:P13569 CFTR  17 0.677 24
 UniProt:Q9HCM9 TRIM39  1 0.666 4
 UniProt:P17813 EGLN      0.61 6
 IntAct:EBI-25865403 EHD27213144      0.556 3
 UniProt:Q14203-5 DCTN1      0.556 3
 UniProt:P09936 UCHL1  1 0.556 3
 UniProt:Q8IZW8 TNS4  1 0.556 3
 UniProt:Q6GPH4 XAF1  1 0.556 3
 UniProt:Q9Y613 FHOD1      0.556 3
 UniProt:Q86VF2-5 IGFN1      0.556 3
 UniProt:Q9NXE8 CWC25  1 0.556 3
 UniProt:Q8TBB1 LNX1  1 0.556 3
 UniProt:Q9Y2B5 VP9D1      0.556 3
 UniProt:P32622 YEF1      0.556 3
 IntAct:EBI-10200347 3500      0.556 3
 IntAct:EBI-10200362 28396      0.556 3
 UniProt:O75382 TRIM3  1 0.556 3
 UniProt:Q96IK5 GMCL1      0.556 3
 UniProt:Q9NPF5 DMAP1  1 0.556 3
 UniProt:Q9NUJ3 T11L1      0.556 3
 UniProt:P42858 HTT  1 0.556 21
 UniProt:O00257-3 CBX4      0.556 3
 UniProt:Q9HCM9-2 TRIM39      0.556 3
 UniProt:O60260-5 PRKN      0.556 3
 UniProt:Q9BW85 YJU2  1 0.556 3
 UniProt:O15296 ALOX15B  1 0.556 3
 UniProt:Q08426 EHHADH  2 0.556 3
 UniProt:Q9Y3C5 RNF11      0.556 3
 UniProt:Q05516 ZBTB16  1 0.556 3
 UniProt:Q9Y4E8 USP25  1 0.556 3
 UniProt:Q8IYI6 EXOC8  2 0.556 3
 UniProt:P37840 SNCA  5 0.556 3
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