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VPS37C [endosome membrane]
Stable Identifier
R-HSA-184438
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endosome membrane
Locations in the PathwayBrowser
Expand all
Autophagy (Homo sapiens)
Late endosomal microautophagy (Homo sapiens)
Substrate translocates into late endosomal lumen (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37C [endosome membrane] (Homo sapiens)
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
HCMV Infection (Homo sapiens)
HCMV Late Events (Homo sapiens)
HCMV Final Envelopment (Homo sapiens)
ESCRT Regulator Complex [cytosol] (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37C [endosome membrane] (Homo sapiens)
HCMV Formation of Final Envelopment Complex (Homo sapiens)
ESCRT Regulator Complex [cytosol] (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37C [endosome membrane] (Homo sapiens)
HIV Infection (Homo sapiens)
HIV Life Cycle (Homo sapiens)
Late Phase of HIV Life Cycle (Homo sapiens)
Assembly Of The HIV Virion (Homo sapiens)
Synthesis And Processing Of GAG, GAGPOL Polyproteins (Homo sapiens)
Membrane binding and targetting of GAG proteins (Homo sapiens)
Monoubiquitinated N-myristoyl GAG polyprotein is targeted to the late endosomal vesicle membrane by the ESCRT-I complex (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37C [endosome membrane] (Homo sapiens)
Transport of GAG to the Plasma Membrane (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37C [endosome membrane] (Homo sapiens)
Budding and maturation of HIV virion (Homo sapiens)
HIV Virion Budding (Homo sapiens)
Virion Budding Complex [plasma membrane] (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37C [endosome membrane] (Homo sapiens)
Recruitment Of HIV Virion Budding Machinery (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37C [endosome membrane] (Homo sapiens)
Virion Budding Complex [plasma membrane] (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37C [endosome membrane] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Endosomal Sorting Complex Required For Transport (ESCRT) (Homo sapiens)
Cargo Recognition And Sorting (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37C [endosome membrane] (Homo sapiens)
ESCRT-I/Cargo Complex [endosome membrane] (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37C [endosome membrane] (Homo sapiens)
Cargo Sequestration (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37C [endosome membrane] (Homo sapiens)
ESCRT-I/Cargo Complex [endosome membrane] (Homo sapiens)
ESCRT-I [endosome membrane] (Homo sapiens)
VPS37 [endosome membrane] (Homo sapiens)
VPS37C [endosome membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:A5D8V6 VPS37C
Gene Names
VPS37C, PML39
Chain
chain:1-355
Reference Genes
BioGPS Gene:55048 VPS37C
COSMIC (genes):VPS37C VPS37C
CTD Gene:55048 VPS37C
dbSNP Gene:55048 VPS37C
ENSEMBL:ENSG00000167987 VPS37C
HGNC:26097 VPS37C
KEGG:hsa:55048 VPS37C
Monarch:55048 VPS37C
NCBI Gene:55048 VPS37C
OMIM:610038 VPS37C
UCSC:A5D8V6 VPS37C
Reference Transcript
RefSeq:XM_005274077.3 VPS37C
RefSeq:NM_017966.4 VPS37C
Other Identifiers
11753096_a_at
11754863_s_at
1560059_PM_at
1560059_at
1560060_PM_s_at
1560060_s_at
16738922
219053_PM_s_at
219053_s_at
3375148
3375149
3375150
3375151
3375152
3375153
3375154
3375155
3375156
3375157
3375158
3375159
3375160
3375161
3375162
3375163
3375164
3375165
3375166
3375168
3375169
3375170
3375182
55048
7948504
90260_at
A_23_P47517
GE55639
GO:0000813
GO:0005515
GO:0005768
GO:0006612
GO:0006623
GO:0006886
GO:0006914
GO:0009056
GO:0010008
GO:0015031
GO:0016020
GO:0016192
GO:0016236
GO:0031410
GO:0031902
GO:0036258
GO:0039702
GO:0043162
GO:0043226
GO:0043328
GO:0048306
GO:0061024
GO:0070062
GO:0090148
HMNXSV003047758
Hs2.376047.1.S1_3p_s_at
ILMN_1789233
PH_hs_0027003
TC11001849.hg
Participates
as a member of
VPS37 [endosome membrane] (Homo sapiens)
Inferred To
VPS37C [endosome membrane]
(Bos taurus)
VPS37C [endosome membrane]
(Canis familiaris)
VPS37C [endosome membrane]
(Gallus gallus)
VPS37C [endosome membrane]
(Sus scrofa)
vps37c [endosome membrane]
(Danio rerio)
SRN2 [endosome membrane]
(Saccharomyces cerevisiae)
Vps37B [endosome membrane]
(Drosophila melanogaster)
vps37 [endosome membrane]
(Dictyostelium discoideum)
vps-37 [endosome membrane]
(Caenorhabditis elegans)
Vps37c [endosome membrane]
(Mus musculus)
Vps37c [endosome membrane]
(Rattus norvegicus)
Cross References
RefSeq
XP_005274134.1
,
NP_060436.4
ENSEMBL
ENSP00000301765
,
ENST00000301765
OpenTargets
ENSG00000167987
HPA
ENSG00000167987-VPS37C
PRO
A5D8V6
Pharos - Targets
A5D8V6
Interactors (14)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P98170 XIAP
3
XIAP [cytosol]
(R-HSA-50849)
K48pUb-XIAP [cytosol]
(R-HSA-5675477)
XIAP [nucleoplasm]
(R-HSA-3322366)
0.781
7
UniProt:O00308 WWP2
1
WWP2 [cytosol]
(R-HSA-6807279)
0.718
6
UniProt:P62993 GRB2
1
GRB2 [cytosol]
(R-HSA-8983328)
0.556
3
UniProt:Q08117 TLE5
1
AES [nucleoplasm]
(R-HSA-4648963)
0.556
3
UniProt:O95429 BAG4
3
BAG4 [cytosol]
(R-HSA-5212670)
BAG4(1-126)-p-8Y-FGFR1(208-822) fusion [plasma membrane]
(R-HSA-8853156)
BAG4(1-126)-FGFR1(208-822) fusion [plasma membrane]
(R-HSA-8853157)
0.556
3
UniProt:Q08379 GOLGA2
3
p-S37-GOLGA2 [Golgi membrane]
(R-HSA-2172179)
GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-2167933)
GOLGA2 [Golgi membrane]
(R-HSA-6808764)
0.556
3
UniProt:Q9UBB9 TFIP11
1
TFIP11 [nucleoplasm]
(R-HSA-8869310)
0.556
3
UniProt:Q13227 GPS2
1
GPS2 [nucleoplasm]
(R-HSA-351642)
0.556
3
UniProt:P25788 PSMA3
2
PSMA3 [cytosol]
(R-HSA-68728)
PSMA3 [nucleoplasm]
(R-HSA-174323)
0.556
3
UniProt:O14964 HGS
2
HGS [cytosol]
(R-HSA-182954)
HGS [phagocytic vesicle lumen]
(R-HSA-9635660)
0.556
3
UniProt:Q96CA5 BIRC7
1
BIRC7 [cytosol]
(R-HSA-50855)
0.556
3
UniProt:P52597 HNRNPF
2
HNRNPF [nucleoplasm]
(R-HSA-71937)
HNRNPF [plasma membrane]
(R-HSA-8950714)
0.556
3
UniProt:Q9Y6A5 TACC3
1
TACC3 [cytosol]
(R-HSA-2160956)
0.556
3
UniProt:P35638 DDIT3
1
DDIT3 [nucleoplasm]
(R-HSA-381110)
0.556
3
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