Reactome | MEN1 [nucleoplasm]

Stable Identifier

R-HSA-2186626

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Menin, SCG2

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O00255 MEN1

Gene Names

MEN1, SCG2

Chain

chain:1-610

Reference Genes

COSMIC (genes):MEN1 MEN1

COSMIC (genes):SCG2 MEN1

dbSNP Gene:4221 MEN1

ENSEMBL:ENSG00000133895 MEN1

Participates

as an input of

as a component of

as an output of

Other forms of this molecule

MEN1 [cytosol]

p-MEN1 [endoplasmic reticulum lumen]

MEN1 [endoplasmic reticulum lumen]

Inferred To

Men1 [nucleoplasm] (Mus musculus)

Men1 [nucleoplasm] (Rattus norvegicus)

Mnn1 [nucleoplasm] (Drosophila melanogaster)

men1 [nucleoplasm] (Danio rerio)

MEN1 [nucleoplasm] (Bos taurus)

MEN1 [nucleoplasm] (Canis familiaris)

MEN1 [nucleoplasm] (Sus scrofa)

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P61964 WDR5	1	WDR5 [nucleoplasm] (R-HSA-1629838)	0.708	4
UniProt:Q03164 KMT2A	6	KMT2A [cytosol] (R-HSA-9818584) KMT2A(2719-3969) [cytosol] (R-HSA-9818590) KMT2A(1-2718) [cytosol] (R-HSA-9818597) KMT2A [nucleoplasm] (R-HSA-1183223) KMT2A(1-2718) [nucleoplasm] (R-HSA-9818591) KMT2A(2719-3969) [nucleoplasm] (R-HSA-9818593)	0.643	3
UniProt:P35579 MYH9	3	MYH9 [cytosol] (R-HSA-419173) MYH9(2-1644)-ALK(1067-1620) fusion [cytosol] (R-HSA-9715280) MYH9(2-1644)-p-7Y-ALK(1067-1620) fusion [cytosol] (R-HSA-9715279)	0.556	3
UniProt:P19838-PRO_0000030311 NFKB1			0.524	2
UniProt:Q9BXW9 FANCD2	3	FANCD2 [nucleoplasm] (R-HSA-419522) p-T691,S717-FANCD2 [nucleoplasm] (R-HSA-6788481) MonoUb-K561,p-T691,S717-FANCD2 [nucleoplasm] (R-HSA-6785318)	0.524	4
UniProt:Q9UMN6 KMT2B	5	KMT2B [cytosol] (R-HSA-9818624) KMT2B(2-2062) [cytosol] (R-HSA-9818621) KMT2B(2063-2715) [cytosol] (R-HSA-9818626) KMT2B(2063-2715) [nucleoplasm] (R-HSA-9818623) KMT2B(2-2062) [nucleoplasm] (R-HSA-9818620)	0.462	2

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