Reactome | DEK [nucleoplasm]

DEK [nucleoplasm]

Stable Identifier

R-HSA-5250643

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Protein DEK, DEK_HUMAN

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Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P35659 DEK

Gene Names

DEK

Chain

initiator methionine:, chain:2-375

Reference Genes

BioGPS Gene:7913 DEK

COSMIC (genes):DEK DEK

CTD Gene:7913 DEK

dbSNP Gene:7913 DEK

ENSEMBL:ENSG00000124795 DEK

ENSEMBL_homo_sapiens_GENE:ENSG00000124795.17 DEK

HGNC:2768 DEK

KEGG Gene (Homo sapiens):7913 DEK

Monarch:7913 DEK

NCBI Gene:7913 DEK

OMIM:125264 DEK

UCSC:P35659 DEK

Reference Transcript

Other Identifiers

11741575_a_at

11743650_s_at

11743651_a_at

11743652_a_at

11743653_x_at

11751258_x_at

11757280_s_at

17015987

200934_PM_at

200934_at

2944065

2944067

2944069

2944070

2944071

2944073

2944077

2944078

2944079

2944086

2944087

2944090

2944091

2944093

2944094

2944096

2944097

2944099

2944100

38992_at

7913

8124144

GE79096

GO:0003677

GO:0003723

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0005730

GO:0006281

GO:0006325

GO:0006338

GO:0006351

GO:0006355

GO:0006357

GO:0006366

GO:0007165

GO:0019079

GO:0023052

GO:0035066

GO:0036211

GO:0042393

GO:0043226

GO:0043292

GO:0045943

GO:0045944

GO:0045945

GO:0110016

GO:2000779

GO:2001032

HMNXSV003036413

ILMN_1747630

PH_hs_0006093

TC06001302.hg

X64229_at

g4503248_3p_at

Participates

as an input of

as a component of

Inferred To

DEK [nucleoplasm] (Bos taurus)

DEK [nucleoplasm] (Canis familiaris)

DEK [nucleoplasm] (Gallus gallus)

DEK [nucleoplasm] (Sus scrofa)

Homologues of DEK [nucleoplasm] (Canis familiaris)

LOC100688177 [nucleoplasm] (Canis familiaris)

Ghost homologue of DEK [nucleoplasm] (Caenorhabditis elegans)

Dek [nucleoplasm] (Drosophila melanogaster)

Dek [nucleoplasm] (Mus musculus)

Dek [nucleoplasm] (Rattus norvegicus)

dek [nucleoplasm] (Xenopus tropicalis)

Cross References

RefSeq

NP_003463.1, NP_001128181.1

OpenTargets

ENSG00000124795

GeneCards

P35659

HPA

ENSG00000124795-DEK

Ensembl

ENSP00000244776, ENSP00000498653, ENST00000652576, ENST00000244776, ENSP00000498335, ENST00000652689, ENSG00000124795

PRO

P35659

Pharos - Targets

P35659

Orphanet

17760

PDB

2JX3, 1Q1V

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P68400 CSNK2A1	2	CSNK2A1 [nucleoplasm] (R-HSA-6805057) CSNK2A1 [cytosol] (R-HSA-201713)	0.688	3
UniProt:P19784 CSNK2A2	2	CSNK2A2 [nucleoplasm] (R-HSA-6805065) CSNK2A2 [cytosol] (R-HSA-201721)	0.643	3
UniProt:Q8N954-2 GPATCH11			0.556	3
UniProt:Q9UER7 DAXX	13	monoSUMO1-K630,K631-DAXX [nucleoplasm] (R-HSA-4086086) DAXX L98Vfs13 [nucleoplasm] (R-HSA-9673102) DAXX R48Vfs93 [nucleoplasm] (R-HSA-9673103) DAXX C74* [nucleoplasm] (R-HSA-9673096) DAXX S138* [nucleoplasm] (R-HSA-9673081) DAXX H26Tfs118 [nucleoplasm] (R-HSA-9673114) DAXX E104 [nucleoplasm] (R-HSA-9673078) DAXX E72Nfs72 [nucleoplasm] (R-HSA-9673110) DAXX C106 [nucleoplasm] (R-HSA-9673079) DAXX A103Sfs40 [nucleoplasm] (R-HSA-9673121) DAXX K56 [nucleoplasm] (R-HSA-9673089) DAXX A36Qfs*108 [nucleoplasm] (R-HSA-9673105) DAXX [nucleoplasm] (R-HSA-3222068)	0.499	2
UniProt:P68431 HIST1H3G	20	2xAcK-HIST1H3A [nucleoplasm] (R-HSA-427507) Ack-Me3K5-HIST1H3A [nucleoplasm] (R-HSA-4551293) AcK-Me3K10-HIST1H3A [nucleoplasm] (R-HSA-4551291) AcK-Me3K28-HIST1H3A [nucleoplasm] (R-HSA-4551292) Me2aR27-HIST1H3A [nucleoplasm] (R-HSA-5229052) Me2aR18-HIST1H3A [nucleoplasm] (R-HSA-5229062) Me2sR9-HIST1H3A [nucleoplasm] (R-HSA-5211328) Me2sR3-HIST1H3A [nucleoplasm] (R-HSA-5218935) AcK9,14-p-S10-HIST1H3A [nucleoplasm] (R-HSA-8870893) AcK14,18,79-p-S10-HIST1H3A [nucleoplasm] (R-HSA-8871271) AcK9,14,18-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8871306) AcK14,18-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8871294) AcK9,14,18,79-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8865596) AcK14,18-p-S10-HIST1H3A [nucleoplasm] (R-HSA-8871295) AcK14,18,79-p-T11-HIST1H3A [nucleoplasm] (R-HSA-8871288) AcK14,18-p-T11-HIST1H3A [nucleoplasm] (R-HSA-8871299) AcK14,18,79-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8871286) Me2K28-HIST1H3A [nucleoplasm] (R-HSA-4754193) MeK37-HIST1H3A [nucleoplasm] (R-HSA-4722135) MeK80-HIST1H3A [nucleoplasm] (R-HSA-5649791)	0.483	2

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