Reactome | ALDOA [tertiary granule lumen]

ALDOA [tertiary granule lumen]

Stable Identifier

R-HSA-6801485

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

tertiary granule lumen

Synonyms

Fructose-bisphosphate aldolase A , Muscle-type aldolase, Lung cancer antigen NY-LU-1

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P04075 ALDOA

Gene Names

ALDOA, ALDA

Chain

initiator methionine:, chain:2-364

Reference Genes

BioGPS Gene:226 ALDOA

COSMIC (genes):ALDOA ALDOA

CTD Gene:226 ALDOA

dbSNP Gene:226 ALDOA

ENSEMBL:ENSG00000149925 ALDOA

ENSEMBL_homo_sapiens_GENE:ENSG00000149925.22 ALDOA

HGNC:414 ALDOA

KEGG Gene (Homo sapiens):226 ALDOA

Monarch:226 ALDOA

NCBI Gene:226 ALDOA

OMIM:103850 ALDOA

UCSC:P04075 ALDOA

Reference Transcript

Other Identifiers

11733097_x_at

11745964_x_at

16817790

200966_PM_x_at

200966_x_at

214687_PM_x_at

214687_x_at

226

32336_at

3311650

3655930

3655931

3655932

3655933

3655936

3655937

3655938

3655940

3655943

3655944

3655945

3655948

3655951

3655953

3655954

3655955

3655956

7994737

86570_f_at

A_23_P88963

A_24_P921584

GE59667

GO:0003012

GO:0003723

GO:0003779

GO:0003824

GO:0004332

GO:0005515

GO:0005576

GO:0005615

GO:0005634

GO:0005737

GO:0005829

GO:0005856

GO:0005975

GO:0006000

GO:0006091

GO:0006096

GO:0006754

GO:0006941

GO:0007010

GO:0007015

GO:0007339

GO:0008092

GO:0008360

GO:0015629

GO:0015631

GO:0016020

GO:0016829

GO:0022414

GO:0030388

GO:0031093

GO:0031410

GO:0031430

GO:0031674

GO:0034774

GO:0042802

GO:0043226

GO:0045296

GO:0046716

GO:0048856

GO:0051289

GO:0055086

GO:0061827

GO:0065003

GO:0070061

GO:0070062

GO:1901135

GO:1904724

GO:1904813

HMNXSV003025296

Hs.273415.1.S1_3p_x_at

ILMN_1681374

ILMN_1736700

ILMN_1741148

ILMN_2251253

PH_hs_0028065

X12447_at

Participates

as a member of

Tertiary granule lumen proteins [tertiary granule lumen] (Homo sapiens)

Other forms of this molecule

ALDOA [platelet alpha granule lumen]

ALDOA [secretory granule lumen]

ALDOA [ficolin-1-rich granule lumen]

ALDOA [extracellular region]

ALDOA [cytosol]

Inferred To

ALDOA [tertiary granule lumen] (Bos taurus)

ALDOA [tertiary granule lumen] (Canis familiaris)

ALDOA [tertiary granule lumen] (Mus musculus)

ALDOA [tertiary granule lumen] (Rattus norvegicus)

ALDOA [tertiary granule lumen] (Sus scrofa)

aldoa [tertiary granule lumen] (Xenopus tropicalis)

ALDOC [tertiary granule lumen] (Caenorhabditis elegans)

ALDOC [tertiary granule lumen] (Dictyostelium discoideum)

ALDOC [tertiary granule lumen] (Drosophila melanogaster)

ALDOC [tertiary granule lumen] (Plasmodium falciparum)

Ald2 [tertiary granule lumen] (Drosophila melanogaster)

aldoaa [tertiary granule lumen] (Danio rerio)

Homologues of ALDOC [tertiary granule lumen] (Caenorhabditis elegans)

Homologues of ALDOC [tertiary granule lumen] (Drosophila melanogaster)

Cross References

RefSeq

XP_011544070.1, NP_908932.1, NP_001121089.1, NP_908930.1, NP_001230106.1, NP_000025.1

OpenTargets

ENSG00000149925

IntEnz

4.1.2.13

GeneCards

P04075

HPA

ENSG00000149925-ALDOA

Ensembl

ENSP00000400452, ENST00000563060, ENST00000642816, ENST00000412304, ENSP00000455700, ENSG00000149925, ENSP00000455800, ENSP00000496166, ENST00000643777, ENSP00000494188, ENST00000569545

PRO

P04075

Pharos - Targets

P04075

Orphanet

15491

HMDB Protein

HMDBP00978

PDB

6XMO, 1ALD, 4ALD, 6XMH, 6XMM, 2ALD, 6XML, 5KY6

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.706	18
UniProt:P12004 PCNA	5	monoSUMO1-K164,K254,K-PCNA [nucleoplasm] (R-HSA-4615861) K63polyUb-K164-PCNA [nucleoplasm] (R-HSA-8943000) ISG-K164,ISG-K168-PCNA [nucleoplasm] (R-HSA-5653768) MonoUb-K164-PCNA [nucleoplasm] (R-HSA-5651986) PCNA [nucleoplasm] (R-HSA-68439)	0.571	3
UniProt:P10636-8 MAPT	3	p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol] (R-HSA-9836400) p-S262,S356,S396-MAPT-8 [cytosol] (R-HSA-9619521) MAPT-8 [cytosol] (R-HSA-9619519)	0.569	10
UniProt:P00533 EGFR	20	p-6Y-EGFR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869138) p-5Y-EGFRvIII [plasma membrane] (R-HSA-1248649) EGFRvIII [plasma membrane] (R-HSA-1214162) p-6Y-EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1182985) p-6Y-EGFR L858R;T790M [plasma membrane] (R-HSA-1182984) p-6Y-EGFR A767_V769dup [plasma membrane] (R-HSA-1996343) p-6Y-EGFR N771_H773dup [plasma membrane] (R-HSA-1996342) p-6Y-EGFR K739_I744dup [plasma membrane] (R-HSA-1996346) p-6Y-EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996335) p-6Y-EGFR E746_A750del [plasma membrane] (R-HSA-1181214) p-6Y-EGFR L858R [plasma membrane] (R-HSA-1173211) p-6Y-EGFR G719S [plasma membrane] (R-HSA-1169417) p-6Y-EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228038) p-6Y-EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228044) p-6Y-EGFR L747_T751del [plasma membrane] (R-HSA-1228041) p-6Y-EGFR L747_S752del [plasma membrane] (R-HSA-1228040) p-6Y-EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228042) p-6Y-EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228037) p-6Y-EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228039) p-6Y-EGFR L861Q [plasma membrane] (R-HSA-1177541)	0.553	2
UniProt:P19320 VCAM1	1	VCAM1 [plasma membrane] (R-HSA-197834)	0.527	4
UniProt:Q86X55 CARM1	1	CARM1 [nucleoplasm] (R-HSA-400139)	0.499	2

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