Reactome | COG6 [trans-Golgi network membrane]

COG6 [trans-Golgi network membrane]

Stable Identifier

R-HSA-6813872

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

trans-Golgi network membrane

Synonyms

Conserved oligomeric Golgi complex subunit 6, COG6_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9Y2V7 COG6

Gene Names

COG6, KIAA1134

Chain

chain:1-657

Reference Genes

BioGPS Gene:57511 COG6

COSMIC (genes):COG6 COG6

CTD Gene:57511 COG6

dbSNP Gene:57511 COG6

ENSEMBL:ENSG00000133103.17 COG6

HGNC:18621 COG6

KEGG Gene (Homo sapiens):57511 COG6

Monarch:57511 COG6

NCBI Gene:57511 COG6

OMIM:606977 COG6

UCSC:Q9Y2V7 COG6

Reference Transcript

Other Identifiers

0003290056

11724048_a_at

11724049_a_at

11739210_at

16774188

225769_PM_at

225769_at

232786_PM_at

232786_at

3486384

3486385

3486386

3486387

3486388

3486389

3486390

3486391

3486392

3486394

3486395

3486400

3486402

3486403

3486404

3486408

3486412

3486413

3486414

3486417

3486418

3486419

3486425

3486426

3486427

3486428

3486429

3486430

3486435

3486436

3486441

48586_at

57511

7968711

84000_at

A_14_P102773

A_14_P105706

A_14_P113837

A_23_P53866

A_24_P290692

GE79281

GE87975

GO:0000139

GO:0000301

GO:0005515

GO:0005622

GO:0005737

GO:0005794

GO:0006891

GO:0007030

GO:0015031

GO:0016020

GO:0016192

GO:0017119

GO:0032588

GO:0032991

GO:0043226

GO:0070085

HMNXSV003035609

HMNXSV003046217

Hs.18282.0.S1_3p_at

Hs.18282.1.S1_3p_at

ILMN_1779530

PH_hs_0025461

PH_hs_0041065

TC13000137.hg

TC13001031.hg

Participates

as a component of

COG complex [trans-Golgi network membrane] (Homo sapiens)

Other forms of this molecule

COG6 [Golgi membrane]

Inferred To

cogc-6 [trans-Golgi network membrane] (Caenorhabditis elegans)

cog6 [trans-Golgi network membrane] (Dictyostelium discoideum)

cog6 [trans-Golgi network membrane] (Xenopus tropicalis)

COG6 [trans-Golgi network membrane] (Bos taurus)

COG6 [trans-Golgi network membrane] (Canis familiaris)

COG6 [trans-Golgi network membrane] (Danio rerio)

COG6 [trans-Golgi network membrane] (Gallus gallus)

COG6 [trans-Golgi network membrane] (Saccharomyces cerevisiae)

COG6 [trans-Golgi network membrane] (Sus scrofa)

Cog6 [trans-Golgi network membrane] (Drosophila melanogaster)

Cog6 [trans-Golgi network membrane] (Mus musculus)

Cog6 [trans-Golgi network membrane] (Rattus norvegicus)

Cross References

RefSeq

NP_065802.1, NP_001138551.1

OpenTargets

ENSG00000133103

HPA

ENSG00000133103-COG6

GeneCards

Q9Y2V7

Ensembl

ENST00000416691, ENSP00000397441, ENST00000455146, ENSG00000133103, ENST00000356576, ENSP00000348983, ENSP00000403733

PRO

Q9Y2V7

Pharos - Targets

Q9Y2V7

Orphanet

22399

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O95999 BCL10	3	K48polyUb-BCL10 [cytosol] (R-HSA-8939329) BCL10 [cytosol] (R-HSA-202447) p-BCL10 [cytosol] (R-HSA-202488)	0.696	5
UniProt:O95995 GAS8	1	GAS8 [cytosol] (R-HSA-5633057)	0.556	3
UniProt:P55040 GEM	1	GEM [plasma membrane] (R-HSA-9769962)	0.556	3
UniProt:Q93034 CUL5	2	CUL5 [cytosol] (R-HSA-180528) G76-NEDD8-K724-CUL5 [cytosol] (R-HSA-8952014)	0.556	3
UniProt:P47897 QARS1	2	QARS [cytosol] (R-HSA-379615) QARS [mitochondrial matrix] (R-HSA-379592)	0.556	3
UniProt:O95863 SNAI1	1	SNAI1 [nucleoplasm] (R-HSA-2980903)	0.556	3
UniProt:P55081 MFAP1	1	MFAP1 [nucleoplasm] (R-HSA-2396419)	0.556	3
UniProt:Q9BV20 MRI1	1	MRI1 [cytosol] (R-HSA-1237095)	0.556	3
UniProt:Q08379 GOLGA2	3	p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.488	2
UniProt:O75791 GRAP2	1	GRAP2 [cytosol] (R-HSA-202367)	0.488	2
UniProt:O15287 FANCG	1	FANCG [nucleoplasm] (R-HSA-419532)	0.488	2