Reactome | p-BCL10 [cytosol]

p-BCL10 [cytosol]

Stable Identifier

R-HSA-202488

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

phosphorylated Bcl10

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Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O95999 BCL10

Gene Names

BCL10, CIPER, CLAP

Chain

chain:1-233

Reference Genes

BioGPS Gene:8915 BCL10

COSMIC (genes):BCL10 BCL10

CTD Gene:8915 BCL10

dbSNP Gene:8915 BCL10

ENSEMBL:ENSG00000142867.14 BCL10

HGNC:989 BCL10

KEGG Gene (Homo sapiens):8915 BCL10

Monarch:8915 BCL10

NCBI Gene:8915 BCL10

OMIM:603517 BCL10

UCSC:O95999 BCL10

Reference Transcript

RefSeq:NM_003921.4 BCL10

Other Identifiers

0001780504

11726703_a_at

11726704_x_at

11753497_a_at

16689060

205263_PM_at

205263_at

2420809

2420810

2420811

2420812

2420815

2420816

2420817

2420823

2420824

2420825

2420826

38871_at

74831_r_at

7917338

8915

89594_f_at

A_23_P115286

A_24_P19983

A_33_P3392447

GE79818

GO:0001772

GO:0001783

GO:0001819

GO:0001843

GO:0002020

GO:0002096

GO:0002224

GO:0002250

GO:0002376

GO:0002906

GO:0003713

GO:0005515

GO:0005622

GO:0005634

GO:0005737

GO:0005764

GO:0005773

GO:0005829

GO:0005856

GO:0005881

GO:0005886

GO:0006351

GO:0006355

GO:0006915

GO:0006968

GO:0007155

GO:0007249

GO:0008022

GO:0008219

GO:0009620

GO:0012501

GO:0016020

GO:0016064

GO:0019209

GO:0019899

GO:0019900

GO:0019901

GO:0023052

GO:0031398

GO:0031625

GO:0031663

GO:0032094

GO:0032449

GO:0032755

GO:0032757

GO:0032761

GO:0032765

GO:0032991

GO:0033674

GO:0036211

GO:0042327

GO:0042802

GO:0042981

GO:0043065

GO:0043123

GO:0043226

GO:0043280

GO:0043422

GO:0043621

GO:0044877

GO:0045087

GO:0045121

GO:0045893

GO:0048471

GO:0048856

GO:0050700

GO:0050852

GO:0050856

GO:0050862

GO:0050870

GO:0051059

GO:0051092

GO:0051260

GO:0061760

GO:0065003

GO:0070231

GO:0071222

GO:0071260

GO:0098542

GO:0098772

GO:0140296

GO:2001238

HMNXSV003050401

ILMN_1676874

ILMN_1716446

PH_hs_0011415

TC01002828.hg

g4092066_3p_at

Participates

as an input of

as a component of

Other forms of this molecule

K48polyUb-BCL10 [cytosol]

BCL10 [cytosol]

Inferred To

phospho-Bcl10 [cytosol] (Mus musculus)

phospho-Bcl10 [cytosol] (Rattus norvegicus)

phospho-BCL10 [cytosol] (Bos taurus)

phospho-BCL10 [cytosol] (Gallus gallus)

phospho-BCL10 [cytosol] (Sus scrofa)

phospho-p-BCL10 [cytosol] (Canis familiaris)

phospho-p-BCL10 [cytosol] (Danio rerio)

phospho-bcl10 [cytosol] (Xenopus tropicalis)

Modified Residues

Name

phosphorylated residue at unknown position

PsiMod Name

phosphorylated residue [MOD:00696]

PsiMod Definition

A protein modification that effectively replaces a hydrogen atom with a phosphate group.

Cross References

RefSeq

NP_003912.1

OpenTargets

ENSG00000142867

GeneCards

O95999

HPA

ENSG00000142867-BCL10

Ensembl

ENSG00000142867, ENST00000648566, ENSP00000498104

PRO

O95999

Pharos - Targets

O95999

Orphanet

23652

PDB

6BZE, 2MB9, 6GK2

Interactors (13)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9UDY8 MALT1	1	MALT1 [cytosol] (R-HSA-202461)	0.922	19
UniProt:Q9BXL7 CARD11	5	CARD11 [plasma membrane] (R-HSA-2685592) p-S552,S645-CARD11 [cytosol] (R-HSA-2685625) p-S559,S644,S652-CARD11 [plasma membrane] (R-HSA-1168564) CARD11 [cytosol] (R-HSA-202161) p-S552-CARD11 [cytosol] (R-HSA-202438)	0.857	7
UniProt:Q12933 TRAF2	5	TRAF2 [nucleoplasm] (R-HSA-8862199) K63polyUb-TRAF2 [nucleoplasm] (R-HSA-8862194) K63polyUb-TRAF2 [cytosol] (R-HSA-8862193) PolyUb-TRAF2 [cytosol] (R-HSA-6782848) TRAF2 [cytosol] (R-HSA-66370)	0.805	9
UniProt:Q9Y6K9 IKBKG	12	monoSUMO1-K277,K309-IKBKG [nucleoplasm] (R-HSA-4755449) IKBKG [nucleoplasm] (R-HSA-4755413) IKBKG D406V [cytosol] (R-HSA-5262943) IKBKG L153R [cytosol] (R-HSA-5262879) IKBKG E391* [cytosol] (R-HSA-5262924) IKBKG C417R [cytosol] (R-HSA-5262858) IKBKG R173G [cytosol] (R-HSA-5262966) IKBKG R175P [cytosol] (R-HSA-5262916) IKBKG 420Wro447 [cytosol] (R-HSA-5262978) K63polyUb-IKBKG [cytosol] (R-HSA-202530) Ub-285-IKBKG [cytosol] (R-HSA-741397) IKBKG [cytosol] (R-HSA-168108)	0.789	7
UniProt:O95999 BCL10	3	K48polyUb-BCL10 [cytosol] (R-HSA-8939329) BCL10 [cytosol] (R-HSA-202447) p-BCL10 [cytosol] (R-HSA-202488)	0.749	5
IntAct:EBI-4399559 UBIQ			0.704	5
UniProt:Q9Y2V7 COG6	2	COG6 [trans-Golgi network membrane] (R-HSA-6813872) COG6 [Golgi membrane] (R-HSA-2980958)	0.696	5
UniProt:P31749 AKT1	13	p-T308,S473-AKT1 E17K [nucleoplasm] (R-HSA-2399994) p-T308,S473-AKT1 E17K [cytosol] (R-HSA-2243935) AKT1 E17K [cytosol] (R-HSA-2219526) p-S473-AKT1 E17K [plasma membrane] (R-HSA-2243944) AKT1 E17K [plasma membrane] (R-HSA-1500573) p-T308,S473-AKT1 [plasma membrane] (R-HSA-199430) p-Y315,Y326-AKT1 [cytosol] (R-HSA-8848757) p-T308-AKT1 [cytosol] (R-HSA-198634) AKT1 [cytosol] (R-HSA-58252) AKT1 [plasma membrane] (R-HSA-199416) p-S473-AKT1 [plasma membrane] (R-HSA-377265) p-T308,S473-AKT1 [cytosol] (R-HSA-198356) p-T308,S473-AKT1 [nucleoplasm] (R-HSA-198357)	0.69	5
UniProt:Q96LW7 CAR19			0.602	4
UniProt:Q9H257 CARD9	3	CARD9 [cytosol] (R-HSA-561194) CARD9 [plasma membrane] (R-HSA-5607662) p-T231-CARD9 [plasma membrane] (R-HSA-5607623)	0.547	6
UniProt:P20749 BCL3			0.524	3
UniProt:Q05513 PRKCZ	5	p-T410,T563-PRKCZ [cytosol] (R-HSA-5218698) PRKCZ [cell junction] (R-HSA-2134483) p-T410-PRKCZ [cytosol] (R-HSA-437181) pS, p-T410-PRKCZ [cytosol] (R-HSA-9632824) PRKCZ [cytosol] (R-HSA-58218)	0.518	3
UniProt:Q66677 VCLAP			0.508	2