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LMO2 [nucleoplasm]
Stable Identifier
R-HSA-8956513
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Rhombotin-2, RBTN2_HUMAN, RBTN2, RBTNL1, RHOM2, TTG2, LIM domain only protein 2, T-cell translocation protein 2
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional regulation by RUNX1 (Homo sapiens)
RUNX1 regulates transcription of genes involved in differentiation of HSCs (Homo sapiens)
MYB gene transcription is stimulated by the RUNX1-containing TAL1 complex (Homo sapiens)
RUNX1:CBFB:GATA3-TAL1 core complex,MYB:RUNX1:CBFB:GATA3-TAL1 core complex [nucleoplasm] (Homo sapiens)
MYB:RUNX1:CBFB:GATA3-TAL1 core complex [nucleoplasm] (Homo sapiens)
GATA3-TAL1 core complex [nucleoplasm] (Homo sapiens)
LMO1,LMO2 [nucleoplasm] (Homo sapiens)
LMO2 [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:GATA3-TAL1 core complex [nucleoplasm] (Homo sapiens)
GATA3-TAL1 core complex [nucleoplasm] (Homo sapiens)
LMO1,LMO2 [nucleoplasm] (Homo sapiens)
LMO2 [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:GATA3-TAL1 core complex:MYB gene [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:GATA3-TAL1 core complex,MYB:RUNX1:CBFB:GATA3-TAL1 core complex [nucleoplasm] (Homo sapiens)
MYB:RUNX1:CBFB:GATA3-TAL1 core complex [nucleoplasm] (Homo sapiens)
GATA3-TAL1 core complex [nucleoplasm] (Homo sapiens)
LMO1,LMO2 [nucleoplasm] (Homo sapiens)
LMO2 [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:GATA3-TAL1 core complex [nucleoplasm] (Homo sapiens)
GATA3-TAL1 core complex [nucleoplasm] (Homo sapiens)
LMO1,LMO2 [nucleoplasm] (Homo sapiens)
LMO2 [nucleoplasm] (Homo sapiens)
RUNX1 binds the core TAL1 complex (Homo sapiens)
RUNX1:CBFB:TAL1 core complex [nucleoplasm] (Homo sapiens)
TAL1 core complex [nucleoplasm] (Homo sapiens)
LMO1,LMO2 [nucleoplasm] (Homo sapiens)
LMO2 [nucleoplasm] (Homo sapiens)
TAL1 core complex [nucleoplasm] (Homo sapiens)
LMO1,LMO2 [nucleoplasm] (Homo sapiens)
LMO2 [nucleoplasm] (Homo sapiens)
RUNX1-containing TAL1 complex binds the MYB gene enhancer (Homo sapiens)
RUNX1:CBFB:GATA3-TAL1 core complex,MYB:RUNX1:CBFB:GATA3-TAL1 core complex [nucleoplasm] (Homo sapiens)
MYB:RUNX1:CBFB:GATA3-TAL1 core complex [nucleoplasm] (Homo sapiens)
GATA3-TAL1 core complex [nucleoplasm] (Homo sapiens)
LMO1,LMO2 [nucleoplasm] (Homo sapiens)
LMO2 [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:GATA3-TAL1 core complex [nucleoplasm] (Homo sapiens)
GATA3-TAL1 core complex [nucleoplasm] (Homo sapiens)
LMO1,LMO2 [nucleoplasm] (Homo sapiens)
LMO2 [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:GATA3-TAL1 core complex:MYB gene [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:GATA3-TAL1 core complex,MYB:RUNX1:CBFB:GATA3-TAL1 core complex [nucleoplasm] (Homo sapiens)
MYB:RUNX1:CBFB:GATA3-TAL1 core complex [nucleoplasm] (Homo sapiens)
GATA3-TAL1 core complex [nucleoplasm] (Homo sapiens)
LMO1,LMO2 [nucleoplasm] (Homo sapiens)
LMO2 [nucleoplasm] (Homo sapiens)
RUNX1:CBFB:GATA3-TAL1 core complex [nucleoplasm] (Homo sapiens)
GATA3-TAL1 core complex [nucleoplasm] (Homo sapiens)
LMO1,LMO2 [nucleoplasm] (Homo sapiens)
LMO2 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P25791 LMO2
Gene Names
LMO2, RBTN2, RBTNL1, RHOM2, TTG2
Chain
chain:1-158
Reference Genes
COSMIC (genes):LMO2 LMO2
dbSNP Gene:4005 LMO2
ENSEMBL:ENSG00000135363 LMO2
Participates
as a member of
LMO1,LMO2 [nucleoplasm] (Homo sapiens)
Inferred To
Bx [nucleoplasm]
(Drosophila melanogaster)
Lmo2 [nucleoplasm]
(Mus musculus)
Lmo2 [nucleoplasm]
(Rattus norvegicus)
LMO2 [nucleoplasm]
(Bos taurus)
LMO2 [nucleoplasm]
(Canis familiaris)
LMO2 [nucleoplasm]
(Gallus gallus)
LMO2 [nucleoplasm]
(Sus scrofa)
Interactors (13)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P52272 HNRNPM
1
HNRNPM [nucleoplasm]
(R-HSA-71949)
0.666
4
UniProt:Q96FT9 IFT43
2
IFT43 [ciliary tip]
(R-HSA-5625348)
IFT43 [cilium]
(R-HSA-5617619)
0.556
3
UniProt:Q13464 ROCK1
6
ROCK1 [cytosol]
(R-HSA-212509)
ROCK1(1-1113) [cytosol]
(R-HSA-212523)
ROCK1(1114-1354) [cytosol]
(R-HSA-212524)
Activated ROCK1 [cytosol]
(R-HSA-4687777)
ROCK1 [secretory granule lumen]
(R-HSA-6804967)
ROCK1 [extracellular region]
(R-HSA-6806527)
0.556
3
UniProt:P62993 GRB2
1
GRB2 [cytosol]
(R-HSA-8983328)
0.556
3
UniProt:P07910 HNRNPC
3
HNRNPC [nucleoplasm]
(R-HSA-71933)
SUMO1-K250-HNRNPC [nucleoplasm]
(R-HSA-4570543)
HNRNPC [cytosol]
(R-HSA-9715136)
0.556
3
UniProt:Q7Z3S9 NOTCH2NLA
3
NOTCH2NLA [extracellular region]
(R-HSA-9908935)
NOTCH2NLA(1-?) [extracellular region]
(R-HSA-9911493)
NOTCH2NLA(?-236) [extracellular region]
(R-HSA-9911490)
0.556
3
UniProt:Q08117 TLE5
1
AES [nucleoplasm]
(R-HSA-4648963)
0.556
3
UniProt:P63208 SKP1
2
SKP1 [cytosol]
(R-HSA-174150)
SKP1 [nucleoplasm]
(R-HSA-187538)
0.556
3
UniProt:P14136 GFAP
3
p-GFAP [lysosomal membrane]
(R-HSA-9626054)
GFAP [lysosomal membrane]
(R-HSA-9625195)
GFAP [cytosol]
(R-HSA-1253311)
0.556
3
UniProt:Q08379 GOLGA2
3
p-S37-GOLGA2 [Golgi membrane]
(R-HSA-2172179)
GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-2167933)
GOLGA2 [Golgi membrane]
(R-HSA-6808764)
0.556
3
UniProt:Q8N9N5 BANP
1
BANP [nucleoplasm]
(R-HSA-3221973)
0.556
3
UniProt:P40763 STAT3
12
p-Y705-STAT3 [nucleoplasm]
(R-HSA-1112554)
p-Y705-STAT3 [cytosol]
(R-HSA-914048)
STAT3 [cytosol]
(R-HSA-539044)
p-Y705-STAT3 [cytosol]
(R-HSA-8983130)
p-Y705,S727-STAT3 [cytosol]
(R-HSA-539048)
p-S727-STAT3 [cytosol]
(R-HSA-198705)
p-Y705-STAT3 [nucleoplasm]
(R-HSA-9027589)
p-Y705,S727-STAT3 [nucleoplasm]
(R-HSA-9701429)
AcK685- p-Y705,S727-STAT3 [nucleoplasm]
(R-HSA-9701435)
p-STAT3 [cytosol]
(R-HSA-8982823)
p-STAT3 [nucleoplasm]
(R-HSA-8983188)
Unfolded STAT3 [cytosol]
(R-HSA-6813811)
0.556
3
UniProt:Q04206 RELA
7
RELA [nucleoplasm]
(R-HSA-177676)
RELA [cytosol]
(R-HSA-168172)
p-S276-RELA [nucleoplasm]
(R-HSA-5624468)
p-S276,5xAcK-RELA [nucleoplasm]
(R-HSA-5660642)
polySUMO3-K37,K122,K123-RELA [nucleoplasm]
(R-HSA-4755466)
p-S536-RELA [nucleoplasm]
(R-HSA-9861499)
MeK310-RELA [nucleoplasm]
(R-HSA-8865233)
0.543
3
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