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Active mTORC1 complex [lysosomal membrane]
Stable Identifier
R-HSA-165678
Type
Complex
Species
Homo sapiens
Compartment
lysosomal membrane
Synonyms
mTORC1:Ragulator:Rag:GNP:RHEB:GTP
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by TP53 (Homo sapiens)
TP53 Regulates Metabolic Genes (Homo sapiens)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
MTOR signalling (Homo sapiens)
AKT1S1 (PRAS40) binds mTORC1 (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
Activated Akt1 phosphorylates AKT1S1 (PRAS40) (Homo sapiens)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
Energy dependent regulation of mTOR by LKB1-AMPK (Homo sapiens)
AMPK phosphorylates Raptor in the mTORC1 complex (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
Formation of active mTORC1 complex (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
Phosphorylated AKT1S1:mTORC1 binds YWHAB (Homo sapiens)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Homo sapiens)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1 phosphorylates AKT1S1 (Homo sapiens)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1:YWHAB [lysosomal membrane] (Homo sapiens)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1 [lysosomal membrane] (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Homo sapiens)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1-mediated signalling (Homo sapiens)
Phosphorylation of 4E-BP1 by activated mTORC1 (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Homo sapiens)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1 phosphorylation of RPS6KB1 (S6K) (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Homo sapiens)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
Participants
components
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane]
(Homo sapiens)
RHEB:GTP [lysosomal membrane]
(Homo sapiens)
Participates
as an input of
AMPK phosphorylates Raptor in the mTORC1 complex (Homo sapiens)
AKT1S1 (PRAS40) binds mTORC1 (Homo sapiens)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Homo sapiens)
as a component of
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1 [lysosomal membrane] (Homo sapiens)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Homo sapiens)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Homo sapiens)
as an output of
Formation of active mTORC1 complex (Homo sapiens)
Inferred To
Active mTORC1 complex [lysosomal membrane]
(Bos taurus)
Active mTORC1 complex [lysosomal membrane]
(Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane]
(Canis familiaris)
Active mTORC1 complex [lysosomal membrane]
(Danio rerio)
Active mTORC1 complex [lysosomal membrane]
(Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane]
(Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane]
(Gallus gallus)
Active mTORC1 complex [lysosomal membrane]
(Mus musculus)
Active mTORC1 complex [lysosomal membrane]
(Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane]
(Sus scrofa)
Active mTORC1 complex [lysosomal membrane]
(Xenopus tropicalis)
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