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TMOD3 [cytosol]
Stable Identifier
R-HSA-217354
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Tmod3
Locations in the PathwayBrowser
Expand all
Muscle contraction (Homo sapiens)
Striated Muscle Contraction (Homo sapiens)
ATP Hydrolysis By Myosin (Homo sapiens)
ADP:Calcium Bound Sarcomere Protein Complex [cytosol] (Homo sapiens)
Thin Filament With Troponin Bound Calcium [cytosol] (Homo sapiens)
Tropomodulin [cytosol] (Homo sapiens)
TMOD3 [cytosol] (Homo sapiens)
ATP:Calcium Bound Sarcomere Protein Complex [cytosol] (Homo sapiens)
Thin Filament With Troponin Bound Calcium [cytosol] (Homo sapiens)
Tropomodulin [cytosol] (Homo sapiens)
TMOD3 [cytosol] (Homo sapiens)
Calcium Binds Troponin-C (Homo sapiens)
Calcium Bound Sarcomere Protein Complex [cytosol] (Homo sapiens)
Thin Filament With Troponin Bound Calcium [cytosol] (Homo sapiens)
Tropomodulin [cytosol] (Homo sapiens)
TMOD3 [cytosol] (Homo sapiens)
Inactive Sarcomere Protein Complex [cytosol] (Homo sapiens)
Thin Filament [cytosol] (Homo sapiens)
Tropomodulin [cytosol] (Homo sapiens)
TMOD3 [cytosol] (Homo sapiens)
Myosin Binds ATP (Homo sapiens)
ATP:Calcium Bound Sarcomere Protein Complex [cytosol] (Homo sapiens)
Thin Filament With Troponin Bound Calcium [cytosol] (Homo sapiens)
Tropomodulin [cytosol] (Homo sapiens)
TMOD3 [cytosol] (Homo sapiens)
Calcium Bound Sarcomere Protein Complex [cytosol] (Homo sapiens)
Thin Filament With Troponin Bound Calcium [cytosol] (Homo sapiens)
Tropomodulin [cytosol] (Homo sapiens)
TMOD3 [cytosol] (Homo sapiens)
Release Of ADP From Myosin (Homo sapiens)
ADP:Calcium Bound Sarcomere Protein Complex [cytosol] (Homo sapiens)
Thin Filament With Troponin Bound Calcium [cytosol] (Homo sapiens)
Tropomodulin [cytosol] (Homo sapiens)
TMOD3 [cytosol] (Homo sapiens)
Calcium Bound Sarcomere Protein Complex [cytosol] (Homo sapiens)
Thin Filament With Troponin Bound Calcium [cytosol] (Homo sapiens)
Tropomodulin [cytosol] (Homo sapiens)
TMOD3 [cytosol] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
RHOBTB GTPase Cycle (Homo sapiens)
RHOBTB2 GTPase cycle (Homo sapiens)
RHOBTB2 binds interacting proteins at the endosome membrane (Homo sapiens)
RHOBTB2 interacting proteins [cytosol] (Homo sapiens)
TMOD3 [cytosol] (Homo sapiens)
RHOBTB2:GTP:RHOBTB2 interacting proteins [endosome membrane] (Homo sapiens)
RHOBTB2 interacting proteins [cytosol] (Homo sapiens)
TMOD3 [cytosol] (Homo sapiens)
RND3 GTPase cycle (Homo sapiens)
RND3 binds effectors (Homo sapiens)
RND3 effectors [cytosol] (Homo sapiens)
TMOD3 [cytosol] (Homo sapiens)
RND3:GTP:RND3 effectors [plasma membrane] (Homo sapiens)
RND3 effectors [cytosol] (Homo sapiens)
TMOD3 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NYL9 TMOD3
Gene Names
TMOD3
Chain
chain:1-352
Reference Genes
BioGPS Gene:29766 TMOD3
COSMIC (genes):TMOD3 TMOD3
CTD Gene:29766 TMOD3
dbSNP Gene:29766 TMOD3
ENSEMBL:ENSG00000138594 TMOD3
ENSEMBL_homo_sapiens_GENE:ENSG00000138594.14 TMOD3
HGNC:11873 TMOD3
KEGG Gene (Homo sapiens):29766 TMOD3
Monarch:29766 TMOD3
NCBI Gene:29766 TMOD3
OMIM:605112 TMOD3
UCSC:Q9NYL9 TMOD3
Reference Transcript
RefSeq:NM_014547.4 TMOD3
RefSeq:XM_017022088.1 TMOD3
RefSeq:XM_017022087.1 TMOD3
Other Identifiers
11743613_a_at
11761864_a_at
16801143
220800_PM_s_at
220800_s_at
223077_PM_at
223077_at
223078_PM_s_at
223078_s_at
29766
3594067
3594074
3594075
3594081
3594084
3594085
3594086
3594087
3594089
3594090
3594094
3594095
3594096
3594097
3594098
3594099
3594100
3594101
3594102
3594103
3594104
3594105
3594106
3594107
3594108
3594109
3594110
3594111
3594112
43032_at
46199_at
47605_at
54391_at
59816_i_at
59817_r_at
7983744
A_14_P126711
A_14_P139353
A_23_P65674
A_24_P923113
GE56746
GE79026
GO:0000278
GO:0002376
GO:0003012
GO:0003779
GO:0005523
GO:0005737
GO:0005856
GO:0005865
GO:0005912
GO:0006936
GO:0007010
GO:0007015
GO:0007155
GO:0008092
GO:0030016
GO:0030036
GO:0030154
GO:0030239
GO:0043226
GO:0044772
GO:0048821
GO:0048856
GO:0051694
GO:0065003
GO:0098609
GO:0098631
GO:0098641
GO:1901992
HMNXSV003000561
HMNXSV003030991
Hs.22826.1.S2_3p_at
ILMN_1687865
ILMN_1809484
PH_hs_0001998
TC15000412.hg
g6934243_3p_a_at
g7657648_3p_a_at
Participates
as a candidate of
RND3 effectors [cytosol] (Homo sapiens)
RHOBTB2 interacting proteins [cytosol] (Homo sapiens)
Tropomodulin [cytosol] (Homo sapiens)
Inferred To
Tmod3 [cytosol]
(Mus musculus)
Tmod3 [cytosol]
(Rattus norvegicus)
TMOD3 [cytosol]
(Bos taurus)
TMOD3 [cytosol]
(Canis familiaris)
TMOD3 [cytosol]
(Gallus gallus)
TMOD3 [cytosol]
(Sus scrofa)
tmod3 [cytosol]
(Xenopus tropicalis)
tmod [cytosol]
(Drosophila melanogaster)
tmod2 [cytosol]
(Danio rerio)
Cross References
RefSeq
NP_055362.1
,
XP_016877576.1
,
XP_016877577.1
OpenTargets
ENSG00000138594
HPA
ENSG00000138594-TMOD3
GeneCards
Q9NYL9
Ensembl
ENSP00000308753
,
ENST00000308580
,
ENSG00000138594
PRO
Q9NYL9
Pharos - Targets
Q9NYL9
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P13569 CFTR
17
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.706
21
UniProt:P60709 ACTB
5
Unfolded ACTB [cytosol]
(R-HSA-390462)
ACTB [nucleoplasm]
(R-HSA-3321990)
ACTB [cytosol]
(R-HSA-201861)
ACTB [lysosomal membrane]
(R-HSA-196160)
ACTB [plasma membrane]
(R-HSA-196016)
0.643
4
UniProt:P0DTC2 S
20
S(686-815) [plasma membrane]
(R-COV-9770188)
Spike S2' Fragment [plasma membrane]
(R-COV-9770189)
S1 [plasma membrane]
(R-COV-9769950)
fully glycosylated Spike [plasma membrane]
(R-COV-9733472)
nascent Spike [endoplasmic reticulum lumen]
(R-COV-9694796)
14-sugar N-glycan unfolded Spike [endoplasmic reticulum lumen]
(R-COV-9694459)
Man(9) N-glycan unfolded Spike [endoplasmic reticulum lumen]
(R-COV-9696892)
high-mannose N-glycan unfolded Spike [endoplasmic reticulum lumen]
(R-COV-9696875)
high-mannose N-glycan folded Spike [endoplasmic reticulum lumen]
(R-COV-9696880)
high-mannose N-glycan folded Spike [endoplasmic reticulum-Golgi intermediate compartment]
(R-COV-9766369)
high-mannose N-glycan-PALM-Spike [endoplasmic reticulum-Golgi intermediate compartment]
(R-COV-9696943)
di-antennary N-glycan-PALM-Spike [endoplasmic reticulum-Golgi intermediate compartment]
(R-COV-9696920)
tri-antennary N-glycan-PALM-Spike [endoplasmic reticulum-Golgi intermediate compartment]
(R-COV-9697006)
fully glycosylated Spike [endoplasmic reticulum-Golgi intermediate compartment]
(R-COV-9696997)
complex N-glycan-PALM-Spike S2 Fragment [plasma membrane]
(R-COV-9769952)
fully glycosylated Spike [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-COV-9698330)
fully glycosylated Spike [virion membrane]
(R-COV-9698327)
complex N-glycan-PALM-Spike S1 Fragment [endocytic vesicle membrane]
(R-COV-9694745)
complex N-glycan-PALM-Spike S2 Fragment [endocytic vesicle membrane]
(R-COV-9694343)
complex N-glycan-PALM-Spike S2 Fragment [virion membrane]
(R-COV-9694791)
0.527
2
UniProt:P13196 ALAS1
2
PXLP-ALAS1 [mitochondrial matrix]
(R-HSA-1022086)
ALAS1 [mitochondrial matrix]
(R-HSA-189438)
0.527
2
UniProt:P62736 ACTA2
1
ACTA2 [cytosol]
(R-HSA-445792)
0.527
3
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