Reactome | LONRF1 [cytosol]

LONRF1 [cytosol]

Stable Identifier

R-HSA-8850905

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

LON peptidase N-terminal domain and RING finger protein 1, LONF1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q17RB8 LONRF1

Gene Names

LONRF1, RNF191

Chain

chain:1-773

Reference Genes

BioGPS Gene:91694 LONRF1

COSMIC (genes):LONRF1 LONRF1

CTD Gene:91694 LONRF1

dbSNP Gene:91694 LONRF1

ENSEMBL:ENSG00000154359 LONRF1

HGNC:26302 LONRF1

KEGG:hsa:91694 LONRF1

Monarch:91694 LONRF1

NCBI Gene:91694 LONRF1

UCSC:Q17RB8 LONRF1

Reference Transcript

Other Identifiers

11731076_a_at

11731077_a_at

11757558_s_at

17074815

226038_PM_at

226038_at

3125005

3125006

3125010

3125011

3125013

3125014

3125015

3125016

3125018

3125020

3125021

3125022

3125023

3125024

3125025

3125026

3125027

3125028

3125029

3125030

3125031

3125032

3125038

3125039

3125040

3125041

3125042

3125043

3125044

3125045

3125046

54826_at

8149399

91694

A_23_P94216

A_24_P406480

A_24_P934202

A_32_P194032

GE79015

GO:0003824

GO:0005515

GO:0005737

GO:0005829

GO:0016740

GO:0046872

GO:0061630

GO:0140096

HMNXSV003003529

Hs.180178.0.S1_3p_at

ILMN_1705953

PH_hs_0010665

TC08000997.hg

Participates

as a member of

E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)

Inferred To

lonrf1 [cytosol] (Danio rerio)

Lonrf1 [cytosol] (Mus musculus)

Lonrf1 [cytosol] (Rattus norvegicus)

CG7388 [cytosol] (Drosophila melanogaster)

LONRF1 [cytosol] (Bos taurus)

LONRF1 [cytosol] (Canis familiaris)

LONRF1 [cytosol] (Gallus gallus)

LONRF1 [cytosol] (Plasmodium falciparum)

LONRF1 [cytosol] (Schizosaccharomyces pombe)

LONRF1 [cytosol] (Sus scrofa)

Cross References

ENSEMBL

ENSG00000154359, ENSP00000381298, ENST00000398246

OpenTargets

ENSG00000154359

GeneCards

LONRF1

HPA

ENSG00000154359-LONRF1

PRO

Q17RB8

Pharos - Targets

Q17RB8

GlyGen

Q17RB8

Interactors (21)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O14933 UBE2L6	2	UBE2L6 [cytosol] (R-HSA-936014) UBE2L6 [nucleoplasm] (R-HSA-5653666)	0.781	7
UniProt:P98170 XIAP	3	XIAP [cytosol] (R-HSA-50849) K48pUb-XIAP [cytosol] (R-HSA-5675477) XIAP [nucleoplasm] (R-HSA-3322366)	0.781	7
UniProt:Q13895 BYSL	2	BYSL [nucleoplasm] (R-HSA-6791526) BYSL [cytosol] (R-HSA-6791518)	0.718	8
UniProt:P13196 ALAS1	2	PXLP-ALAS1 [mitochondrial matrix] (R-HSA-1022086) ALAS1 [mitochondrial matrix] (R-HSA-189438)	0.718	6
UniProt:P26367 PAX6	1	PAX6 [nucleoplasm] (R-HSA-3009044)	0.556	3
UniProt:P49639 HOXA1	1	HOXA1 [nucleoplasm] (R-HSA-5617464)	0.556	3
UniProt:Q02548 PAX5	1	PAX5 [nucleoplasm] (R-HSA-158583)	0.556	3
UniProt:P14373 TRIM27	2	TRIM27 [cytosol] (R-HSA-8851002) TRIM27 [nucleoplasm] (R-HSA-2997690)	0.556	3
UniProt:O43597 SPRY2	8	p-Y55-SPRY2 [cytosol] (R-HSA-182950) SPRY2 [plasma membrane] (R-HSA-182924) SPRY2 [cytosol] (R-HSA-182949) p-S112,S115-SPRY2 [cytosol] (R-HSA-1295619) p-Y55,Y227-SPRY2 [plasma membrane] (R-HSA-934555) p-S112,S121-SPRY2 [plasma membrane] (R-HSA-934595) p-S110,S120-SPRY2 [cytosol] (R-HSA-1295590) p-Y55,Y227-SPRY2 [plasma membrane] (R-HSA-1295629)	0.556	3
UniProt:Q9UQK1 PPP1R3C	2	K48polyUb-PPP1R3C [cytosol] (R-HSA-3781005) PPP1R3C [cytosol] (R-HSA-3777102)	0.556	3
UniProt:Q92993 KAT5	1	KAT5 [nucleoplasm] (R-HSA-3321979)	0.556	3
UniProt:Q9NRD5 PICK1	2	PICK1 [plasma membrane] (R-HSA-416989) PICK1 [endocytic vesicle membrane] (R-HSA-417017)	0.556	3
UniProt:Q12933 TRAF2	5	TRAF2 [cytosol] (R-HSA-66370) PolyUb-TRAF2 [cytosol] (R-HSA-6782848) K63polyUb-TRAF2 [cytosol] (R-HSA-8862193) K63polyUb-TRAF2 [nucleoplasm] (R-HSA-8862194) TRAF2 [nucleoplasm] (R-HSA-8862199)	0.556	3
UniProt:P22736 NR4A1	2	NR4A1 [nucleoplasm] (R-HSA-199831) p-S351-NR4A1 [nucleoplasm] (R-HSA-199846)	0.556	3
UniProt:Q7Z3C6 ATG9A	1	ATG9A [phagophore assembly site membrane] (R-HSA-5671732)	0.556	3
UniProt:P25786 PSMA1	2	PSMA1 [cytosol] (R-HSA-68724) PSMA1 [nucleoplasm] (R-HSA-174333)	0.556	3
UniProt:Q9Y5V3 MAGED1	1	MAGED1 [cytosol] (R-HSA-196002)	0.556	3
UniProt:P50458 LHX2	1	LHX2 [nucleoplasm] (R-HSA-9011100)	0.556	3
UniProt:O95391 SLU7	1	hSLU7 [nucleoplasm] (R-HSA-72073)	0.556	3
UniProt:Q06710 PAX8	1	PAX8 [nucleoplasm] (R-HSA-3968418)	0.556	3
UniProt:P31947 SFN	1	SFN [cytosol] (R-HSA-1445105)	0.556	3

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