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PLEC(2396-4684) [cytosol]
Stable Identifier
R-HSA-350618
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Plectin 1 fragment (2396-4684)
Locations in the PathwayBrowser
Expand all
Programmed Cell Death (Homo sapiens)
Apoptosis (Homo sapiens)
Apoptotic execution phase (Homo sapiens)
Apoptotic cleavage of cellular proteins (Homo sapiens)
Caspase-mediated cleavage of cytoskeletal proteins (Homo sapiens)
Caspase-mediated cleavage of plectin-1 (Homo sapiens)
PLEC(2396-4684) [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q15149 PLEC
Gene Names
PLEC, PLEC1
Chain
chain:1-4684
Reference Genes
COSMIC (genes):PLEC PLEC
ENSEMBL:ENSG00000178209 PLEC
HGNC:9069 PLEC
UCSC:Q15149 PLEC
Other Identifiers
11715926_s_at
17082366
201373_3p_at
201373_PM_at
201373_at
216971_PM_s_at
216971_s_at
3157894
3157923
3157924
3157925
3157926
3157927
3157928
3157929
3157930
3157931
3157932
3157933
3157935
3157936
3157937
3157938
3157939
3157940
3157941
3157942
3157943
3157944
3157945
3157946
3157947
3157948
3157949
3157950
3157951
3157952
3157953
3157955
3157956
3157957
3157958
3157959
3157960
3157961
3157963
3157964
3157965
3157966
3157967
3157968
3157969
3157970
3157971
3157972
3157973
3157974
3157975
3157976
3157977
3157978
3157979
3157980
3157981
3157982
3157983
3157984
3157985
3157986
3157987
3157988
3157989
3157990
3157991
3157995
3157996
3157997
3157998
3157999
3158005
3158006
3158009
3158010
38021_at
38022_s_at
5339
73394_f_at
8153568
A_23_P22119
A_24_P913056
A_24_P914759
A_33_P3419098
GE59237
GO:0000902
GO:0002102
GO:0002162
GO:0002376
GO:0002522
GO:0003013
GO:0003334
GO:0003723
GO:0003779
GO:0005198
GO:0005200
GO:0005515
GO:0005737
GO:0005741
GO:0005829
GO:0005856
GO:0005882
GO:0005886
GO:0005903
GO:0005925
GO:0006091
GO:0006997
GO:0007005
GO:0007010
GO:0007015
GO:0007519
GO:0008092
GO:0008104
GO:0008307
GO:0010467
GO:0010761
GO:0010818
GO:0014866
GO:0016528
GO:0019226
GO:0022011
GO:0022904
GO:0030016
GO:0030018
GO:0030036
GO:0030056
GO:0030154
GO:0030216
GO:0030424
GO:0030425
GO:0030506
GO:0031581
GO:0032094
GO:0032287
GO:0034330
GO:0034332
GO:0035264
GO:0042060
GO:0042383
GO:0043034
GO:0043114
GO:0043209
GO:0043226
GO:0043292
GO:0043588
GO:0043933
GO:0045104
GO:0045109
GO:0045111
GO:0045214
GO:0045296
GO:0045445
GO:0048471
GO:0048741
GO:0048856
GO:0048870
GO:0050877
GO:0051015
GO:0055013
GO:0061024
GO:0061436
GO:0070062
GO:0070161
GO:0071260
GO:0071464
GO:0071498
GO:0071944
GO:0120193
GO:2000689
HMNXSV003017729
Hs.79706.2.S1_3p_a_at
ILMN_1685313
ILMN_1709256
ILMN_1717780
ILMN_1736792
ILMN_1744268
ILMN_1757378
ILMN_1788005
ILMN_1801899
PH_hs_0027706
TC08001737.hg
U53204_at
Z54367_s_at
g4505876_3p_s_at
Participates
as an output of
Caspase-mediated cleavage of plectin-1 (Homo sapiens)
Other forms of this molecule
PLEC(1-2395) [cytosol]
PLEC [cytosol]
Inferred To
plec [cytosol]
(Xenopus tropicalis)
Plec [cytosol]
(Mus musculus)
Plec [cytosol]
(Rattus norvegicus)
PLEC [cytosol]
(Bos taurus)
PLEC [cytosol]
(Canis familiaris)
PLEC [cytosol]
(Sus scrofa)
Cross References
ENSEMBL
ENST00000398774
,
ENST00000436759
,
ENSP00000346602
,
ENSP00000348702
,
ENSP00000344848
,
ENST00000354589
,
ENST00000322810
,
ENST00000357649
,
ENST00000354958
,
ENST00000345136
,
ENSP00000347044
,
ENSP00000350277
,
ENSP00000434583
,
ENSP00000381756
,
ENST00000527096
,
ENSP00000388180
,
ENSP00000323856
,
ENST00000356346
OpenTargets
ENSG00000178209
HPA
ENSG00000178209-PLEC
PRO
Q15149
Pharos - Targets
Q15149
GlyGen
Q15149
Orphanet
PLEC
Interactors (11)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.666
4
UniProt:P13569 CFTR
17
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR [endosome membrane]
(R-HSA-6782965)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [lysosomal membrane]
(R-HSA-5627279)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
0.615
20
UniProt:P02533 KRT14
1
KRT14 [cytosol]
(R-HSA-446091)
0.564
2
UniProt:P16144 ITGB4
1
ITGB4 [plasma membrane]
(R-HSA-215947)
0.558
7
UniProt:Q14145 KEAP1
3
KEAP1 [cytosol]
(R-HSA-976038)
ub-KEAP1 [cytosol]
(R-HSA-9766647)
Ub-KEAP1 [cytosol]
(R-HSA-6782766)
0.544
3
UniProt:Q9Y3A5 SBDS
0.536
2
UniProt:Q9H4A3 WNK1
1
WNK1 [cytosol]
(R-HSA-2672391)
0.534
2
UniProt:Q92731 ESR2
5
ESR2 [cytosol]
(R-HSA-9020970)
ESR2 [nucleoplasm]
(R-HSA-446165)
Me-PalmS-ESR2 [plasma membrane]
(R-HSA-9637787)
PalmS-ESR2 [plasma membrane]
(R-HSA-9021059)
PalmS-ESR2 [cytosol]
(R-HSA-9020979)
0.527
2
UniProt:P10636-8 MAPT
3
MAPT-8 [cytosol]
(R-HSA-9619519)
p-S262,S356,S396-MAPT-8 [cytosol]
(R-HSA-9619521)
p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol]
(R-HSA-9836400)
0.527
5
UniProt:P35637 FUS
1
FUS [nucleoplasm]
(R-HSA-72040)
0.518
4
ChEBI:16851 1-PHOSPHATIDYL-1D-MYO-INOSITOL 3,5-BISPHOSPHATE
0.462
2
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