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3OHP62-RPS23 [nucleoplasm]
Stable Identifier
R-HSA-9630773
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
3OHP62-40S ribosomal protein S23
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Homo sapiens)
Protein hydroxylation (Homo sapiens)
OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 (Homo sapiens)
3OHP62-RPS23 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P62266 RPS23
Gene Names
RPS23
Chain
initiator methionine:, chain:2-143
Reference Genes
BioGPS Gene:6228 RPS23
COSMIC (genes):RPS23 RPS23
CTD Gene:6228 RPS23
dbSNP Gene:6228 RPS23
ENSEMBL:ENSG00000186468 RPS23
HGNC:10410 RPS23
KEGG:hsa:6228 RPS23
Monarch:6228 RPS23
NCBI Gene:6228 RPS23
OMIM:603683 RPS23
UCSC:P62266 RPS23
Reference Transcript
RefSeq:NM_001025.4 RPS23
Other Identifiers
11719782_a_at
11719783_at
11719784_x_at
16997751
200926_PM_at
200926_at
227722_PM_at
227722_at
2367246
2744238
2831286
2865052
2865053
2865054
2865055
2865056
2865057
2865058
2865059
2865060
2865061
2865062
2865063
2865064
2865065
2865066
2865067
2865068
2865069
2865070
2865071
2865072
2865073
2865074
2865075
2865076
2865077
347_s_at
3980725
3980726
50961_at
6228
74562_f_at
8112961
A_33_P3257714
D14530_at
GE57529
GE80974
GE86226
GO:0002181
GO:0003723
GO:0003735
GO:0005198
GO:0005515
GO:0005634
GO:0005654
GO:0005730
GO:0005737
GO:0005783
GO:0005791
GO:0005829
GO:0005840
GO:0006412
GO:0015935
GO:0016020
GO:0022626
GO:0022627
GO:0032040
GO:0034063
GO:0042274
GO:0043226
GO:0045202
GO:1990145
GO:1990904
HMNXSV003025193
Hs.107187.2.S1_3p_at
ILMN_1652073
ILMN_1772459
PH_hs_0029995
TC05001547.hg
g4506700_3p_at
Participates
as an output of
OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 (Homo sapiens)
Other forms of this molecule
RPS23 [cytosol]
RPS23 [nucleoplasm]
Inferred To
rps23 [nucleoplasm]
(Danio rerio)
rps23 [nucleoplasm]
(Dictyostelium discoideum)
rps23 [nucleoplasm]
(Schizosaccharomyces pombe)
rps23 [nucleoplasm]
(Xenopus tropicalis)
rps-23 [nucleoplasm]
(Caenorhabditis elegans)
RPS23A [nucleoplasm]
(Saccharomyces cerevisiae)
Rps23 [nucleoplasm]
(Mus musculus)
Rps23 [nucleoplasm]
(Rattus norvegicus)
RPS23B [nucleoplasm]
(Saccharomyces cerevisiae)
RpS23 [nucleoplasm]
(Drosophila melanogaster)
Homologues of 3OHP62-RPS23 [nucleoplasm]
(Saccharomyces cerevisiae)
Homologues of 3OHP62-RPS23 [nucleoplasm]
(Schizosaccharomyces pombe)
Homologues of 3OHP62-RPS23 [nucleoplasm]
(Sus scrofa)
3OHP62-RPS23 [nucleoplasm]
(Gallus gallus)
3OHP62-RPS23 [nucleoplasm]
(Plasmodium falciparum)
3OHP62-RPS23 [nucleoplasm]
(Sus scrofa)
RPS23 [nucleoplasm]
(Bos taurus)
RPS23 [nucleoplasm]
(Canis familiaris)
RPS23 [nucleoplasm]
(Sus scrofa)
rps2302 [nucleoplasm]
(Schizosaccharomyces pombe)
Modified Residues
Name
3-hydroxy-L-proline at 62
Coordinate
62
PsiMod Name
(2S,3S)-3-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 3-hydroxy-L-proline.
Cross References
RefSeq
NP_001016.1
OpenTargets
ENSG00000186468
ENSEMBL
ENSP00000296674
,
ENSP00000498621
,
ENST00000651545
,
ENST00000296674
HPA
ENSG00000186468-RPS23
PRO
P62266
Pharos - Targets
P62266
GlyGen
P62266
PDB
6ZV6
,
7MQA
,
6Z6L
,
6ZVH
,
7XNY
,
8QOI
,
6Z6M
,
4CXG
,
4CXH
,
6ZMO
,
7R4X
,
8IFE
,
6OM7
,
6ZXG
,
6ZUO
,
6ZXF
,
8XXL
,
6ZN5
,
7WTW
,
8XXN
,
7WTU
,
8Y0X
,
6G51
,
5VYC
,
8JDK
,
6G18
,
8JDM
,
7XNX
,
7WTV
,
8PPK
,
4UG0
,
8JDL
,
7A09
,
6ZM7
,
6IP8
,
6ZLW
,
6ZOK
,
6YBW
,
6IP6
,
6ZME
,
6Y2L
,
6G5I
,
6QZP
,
6G5H
,
5T2C
,
6ZP4
,
7QP6
,
6ZMW
,
7WTZ
,
7WTX
,
8IFD
,
6Z6N
,
8XXM
,
6G53
,
6OLI
,
6OM0
,
6G4W
,
6Y0G
,
4V6X
,
8T4S
,
6ZOJ
,
5LKS
,
6ZXH
,
5AJ0
,
7WTS
,
7MQ8
,
6OLG
,
7WTT
,
6OLZ
,
8Y0W
,
6G4S
,
6ZMT
,
8JDJ
,
6OLF
,
6OLE
,
6ZMI
,
6ZVJ
,
5A2Q
,
7K5I
,
6ZON
,
6XA1
,
7WU0
,
6FEC
,
6IP5
,
5OA3
,
7TQL
,
7MQ9
,
6ZXD
,
5FLX
,
6Y57
,
6ZXE
,
8OZ0
,
7QP7
Interactors (8)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P63244 RACK1
1
GNB2L1 [cytosol]
(R-HSA-5626956)
0.638
3
UniProt:P26196 DDX6
1
DDX6 [cytosol]
(R-HSA-430032)
0.615
3
UniProt:P46777 RPL5
1
RPL5 [cytosol]
(R-HSA-72482)
0.564
2
UniProt:Q8N543 OGFOD1
1
OGFOD1 [nucleoplasm]
(R-HSA-2980928)
0.556
3
UniProt:Q15843 NEDD8
8
C111-AcM-UBE2M-G76-NEDD8 [nucleoplasm]
(R-HSA-8952504)
NEDD8 [nucleoplasm]
(R-HSA-8955926)
C111-AcM-UBE2M-G76-NEDD8 [cytosol]
(R-HSA-4419895)
NEDD8 [cytosol]
(R-HSA-416969)
C237-UBA3-G76-NEDD8 [cytosol]
(R-HSA-8951647)
NEDD8(1-81) [cytosol]
(R-HSA-5690794)
NEDD8(77-81) [cytosol]
(R-HSA-6782654)
C116-AcM-UBE2F-G76-NEDD8 [cytosol]
(R-HSA-8951739)
0.527
2
UniProt:Q5S007 LRRK2
1
LRRK2 [cytosol]
(R-HSA-5661173)
0.525
2
UniProt:P13569 CFTR
17
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR [endosome membrane]
(R-HSA-6782965)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [lysosomal membrane]
(R-HSA-5627279)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
0.483
12
UniProt:P03372 ESR1
10
ESR1 [cytosol]
(R-HSA-9020968)
ESR1 [nucleoplasm]
(R-HSA-446168)
Me260-PalmS-ESR1 [plasma membrane]
(R-HSA-9637788)
PalmS-ESR1 [plasma membrane]
(R-HSA-9021057)
PalmS-ESR1 [cytosol]
(R-HSA-9020974)
Me260-ESR1 [cytosol]
(R-HSA-9632177)
p-S167-ESR1 [cytosol]
(R-HSA-9841254)
p-S167-ESR1 [nucleoplasm]
(R-HSA-9841867)
monoSUMO1-5K-ESR1 [nucleoplasm]
(R-HSA-4090302)
p-S118-ESR1 [nucleoplasm]
(R-HSA-9024210)
0.462
2
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