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ANXA1 [cytosol]
Stable Identifier
R-HSA-5263630
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Annexin A1, ANXA1_HUMAN
Locations in the PathwayBrowser
Expand all
Muscle contraction (Homo sapiens)
Smooth Muscle Contraction (Homo sapiens)
CAV3:TRIM72:DYSF binds ANXAs (Homo sapiens)
ANXA1 [cytosol] (Homo sapiens)
CAV3:TRIM72:DYSF:ANXA6:ANXA1:ANXA2 [plasma membrane] (Homo sapiens)
ANXA1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P04083 ANXA1
Gene Names
ANXA1, ANX1, LPC1
Chain
initiator methionine:, chain:2-346, peptide:2-26
Reference Genes
BioGPS Gene:301 ANXA1
COSMIC (genes):ANXA1 ANXA1
CTD Gene:301 ANXA1
dbSNP Gene:301 ANXA1
ENSEMBL:ENSG00000135046 ANXA1
HGNC:533 ANXA1
KEGG:hsa:301 ANXA1
Monarch:301 ANXA1
NCBI Gene:301 ANXA1
OMIM:151690 ANXA1
UCSC:P04083 ANXA1
Reference Transcript
RefSeq:XM_011518609.1 ANXA1
RefSeq:NM_000700.2 ANXA1
Other Identifiers
11717514_a_at
11744953_a_at
11744954_x_at
11744955_a_at
11759797_at
17085901
201012_PM_at
201012_at
301
3174821
3174824
3174828
3174829
3174830
3174831
3174832
3174833
3174834
3174835
3174836
3174838
3174840
3174841
3174842
3174843
3174845
3174846
3174847
3174848
3174850
3174851
3174852
3174853
3174856
3174857
37403_at
8155849
A_14_P122797
A_23_P94501
GE59671
GO:0001533
GO:0001780
GO:0001786
GO:0001891
GO:0002250
GO:0002376
GO:0002548
GO:0002685
GO:0004859
GO:0005102
GO:0005509
GO:0005515
GO:0005543
GO:0005544
GO:0005576
GO:0005615
GO:0005634
GO:0005654
GO:0005737
GO:0005768
GO:0005769
GO:0005829
GO:0005884
GO:0005886
GO:0005912
GO:0005925
GO:0005929
GO:0006909
GO:0006954
GO:0007010
GO:0007155
GO:0007165
GO:0007166
GO:0007187
GO:0008289
GO:0008360
GO:0009986
GO:0010008
GO:0010165
GO:0012506
GO:0014839
GO:0016020
GO:0016192
GO:0016323
GO:0016324
GO:0016328
GO:0018149
GO:0019834
GO:0022414
GO:0030036
GO:0030073
GO:0030154
GO:0030216
GO:0030312
GO:0030850
GO:0031012
GO:0031018
GO:0031340
GO:0031394
GO:0031410
GO:0031514
GO:0031901
GO:0031982
GO:0032355
GO:0032508
GO:0032652
GO:0032717
GO:0032743
GO:0033031
GO:0035924
GO:0042063
GO:0042102
GO:0042119
GO:0042127
GO:0042383
GO:0043066
GO:0043226
GO:0043227
GO:0043434
GO:0045087
GO:0045627
GO:0045629
GO:0045920
GO:0046632
GO:0046872
GO:0046883
GO:0048306
GO:0048856
GO:0048870
GO:0050482
GO:0050727
GO:0062023
GO:0070062
GO:0070301
GO:0070365
GO:0070459
GO:0070555
GO:0071385
GO:0071621
GO:0090050
GO:0090303
GO:0097350
GO:0098542
GO:0098609
GO:0098631
GO:0098641
GO:0098772
GO:1900087
HMNXSV003032171
ILMN_2184184
PH_hs_0023492
TC09000335.hg
X05908_at
g4502100_3p_s_at
Participates
as a component of
CAV3:TRIM72:DYSF:ANXA6:ANXA1:ANXA2 [plasma membrane] (Homo sapiens)
as an input of
CAV3:TRIM72:DYSF binds ANXAs (Homo sapiens)
Other forms of this molecule
ANXA1 [extracellular region]
Cross References
RefSeq
NP_000691.1
,
XP_011516911.1
ENSEMBL
ENSP00000257497
,
ENST00000257497
,
ENSP00000366109
,
ENST00000376911
OpenTargets
ENSG00000135046
HPA
ENSG00000135046-ANXA1
PRO
P04083
Pharos - Targets
P04083
GlyGen
P04083
HMDB Protein
HMDBP07452
PDB
1AIN
,
5VFW
,
1QLS
,
1BO9
Interactors (15)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P00533 EGFR
20
p-6Y-EGFR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869138)
p-5Y-EGFRvIII [plasma membrane]
(R-HSA-1248649)
EGFRvIII [plasma membrane]
(R-HSA-1214162)
p-6Y-EGFR E746_A750del;T790M [plasma membrane]
(R-HSA-1182985)
p-6Y-EGFR L858R;T790M [plasma membrane]
(R-HSA-1182984)
p-6Y-EGFR A767_V769dup [plasma membrane]
(R-HSA-1996343)
p-6Y-EGFR N771_H773dup [plasma membrane]
(R-HSA-1996342)
p-6Y-EGFR K739_I744dup [plasma membrane]
(R-HSA-1996346)
p-6Y-EGFR D770_N771insNPG [plasma membrane]
(R-HSA-1996335)
p-6Y-EGFR E746_A750del [plasma membrane]
(R-HSA-1181214)
p-6Y-EGFR L858R [plasma membrane]
(R-HSA-1173211)
p-6Y-EGFR G719S [plasma membrane]
(R-HSA-1169417)
p-6Y-EGFR L747_P753delinsS [plasma membrane]
(R-HSA-1228038)
p-6Y-EGFR L747_A750delinsP [plasma membrane]
(R-HSA-1228044)
p-6Y-EGFR L747_T751del [plasma membrane]
(R-HSA-1228041)
p-6Y-EGFR L747_S752del [plasma membrane]
(R-HSA-1228040)
p-6Y-EGFR L747_T751delinsP [plasma membrane]
(R-HSA-1228042)
p-6Y-EGFR E746_T751delinsA [plasma membrane]
(R-HSA-1228037)
p-6Y-EGFR E746_S752delinsV [plasma membrane]
(R-HSA-1228039)
p-6Y-EGFR L861Q [plasma membrane]
(R-HSA-1177541)
0.772
5
UniProt:P13569 CFTR
17
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR [endosome membrane]
(R-HSA-6782965)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [lysosomal membrane]
(R-HSA-5627279)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
0.615
10
UniProt:A0A0F6B1Q8 A0A0F6B1Q8
0.558
3
UniProt:Q96EF9 ZHX1R
0.556
3
UniProt:Q6P5S2 LEG1H
0.556
3
UniProt:Q9Y6K9 IKBKG
12
IKBKG [cytosol]
(R-HSA-168108)
Ub-285-IKBKG [cytosol]
(R-HSA-741397)
K63polyUb-IKBKG [cytosol]
(R-HSA-202530)
IKBKG [nucleoplasm]
(R-HSA-4755413)
monoSUMO1-K277,K309-IKBKG [nucleoplasm]
(R-HSA-4755449)
IKBKG *420Wext*447 [cytosol]
(R-HSA-5262978)
IKBKG R175P [cytosol]
(R-HSA-5262916)
IKBKG R173G [cytosol]
(R-HSA-5262966)
IKBKG C417R [cytosol]
(R-HSA-5262858)
IKBKG E391* [cytosol]
(R-HSA-5262924)
IKBKG L153R [cytosol]
(R-HSA-5262879)
IKBKG D406V [cytosol]
(R-HSA-5262943)
0.556
6
UniProt:Q9NVM1 EVA1B
0.556
3
UniProt:Q9C0E8-2 LNPK
0.556
3
UniProt:Q13546 RIPK1
20
RIPK1 [cytosol]
(R-HSA-168651)
RIPK1 [endosome membrane]
(R-HSA-450326)
K63polyUb-RIPK1 [cytosol]
(R-HSA-937021)
p-S166-RIPK1 [cytosol]
(R-HSA-5218872)
p-S357-RIPK1 [cytosol]
(R-HSA-9819116)
p-S320-RIPK1 [cytosol]
(R-HSA-9815498)
K63,M1polyUb, p-T189-RIPK1 [cytosol]
(R-HSA-9817377)
polyUb-K377,K604,K634-RIPK1 [cytosol]
(R-HSA-9818391)
RIPK1(325-671) [cytosol]
(R-HSA-5212671)
RIPK1(1-324) [cytosol]
(R-HSA-5212664)
K63,M1polyUb-RIPK1 [cytosol]
(R-HSA-9793681)
K63,Met1polyUb-p-S25-RIPK1 [cytosol]
(R-HSA-9818793)
K48polyUb-K571,K604,K627-RIPK1 [cytosol]
(R-HSA-9796639)
RIPK1 [plasma membrane]
(R-HSA-937073)
RIPK1 D324H [cytosol]
(R-HSA-9693922)
RIPK1 D324V [cytosol]
(R-HSA-9693927)
RIPK1 D324Y [cytosol]
(R-HSA-9693931)
RIPK1 D324N [cytosol]
(R-HSA-9693930)
PolyUb-RIPK1 [cytosol]
(R-HSA-6783197)
K48polyUb-RIPK1 [cytosol]
(R-HSA-6783308)
0.556
5
UniProt:P43631 KIR2DS2
1
KIR2DS2 [plasma membrane]
(R-HSA-199534)
0.527
2
UniProt:P62879 GNB2
4
GNB2 [cytosol]
(R-HSA-6814421)
Partially folded GNB2 [cytosol]
(R-HSA-8850536)
Unfolded GNB2 [cytosol]
(R-HSA-6814202)
GNB2 [plasma membrane]
(R-HSA-164335)
0.527
2
UniProt:Q8N878 FRMD1
0.527
2
UniProt:Q13043 STK4
4
STK4(1-487) [cytosol]
(R-HSA-201627)
STK4(327-487) [cytosol]
(R-HSA-2028668)
p-T183-STK4(1-487) [cytosol]
(R-HSA-2028258)
p-T183-STK4(1-326) [cytosol]
(R-HSA-2028682)
0.527
2
UniProt:A0A0F6B5H5 A0A0F6B5H5
0.499
2
UniProt:A0A0F6AZQ1 A0A0F6AZQ1
0.499
2
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