Reactome | SNRPA [nucleoplasm]

SNRPA [nucleoplasm]

Stable Identifier

R-HSA-71915

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

U1 -A protein, RU1A_HUMAN, U1 small nuclear ribonucleoprotein A, U1 snRNP A protein

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P09012 SNRPA

Gene Names

SNRPA

Chain

initiator methionine:1, chain:2-282

Reference Genes

BioGPS Gene:6626 SNRPA

COSMIC - genes:SNRPA SNRPA

CTD Gene:6626 SNRPA

dbSNP Gene:6626 SNRPA

ENSEMBL:ENSG00000077312 SNRPA

HGNC:11151 SNRPA

KEGG:hsa:6626 SNRPA

Monarch:6626 SNRPA

NCBI Gene:6626 SNRPA

OMIM:182285 SNRPA

UCSC:P09012 SNRPA

Reference Transcript

RefSeq:NM_004596.5 SNRPA

Other Identifiers

11744270_a_at

11748453_x_at

11756298_a_at

11756299_x_at

16862333

201770_PM_at

201770_at

3833760

3833761

3833762

3833763

3833764

3833766

3833767

3833768

3833770

3833771

3833772

3833773

3833774

3833775

3833776

3833779

3833780

3833788

40842_at

6626

8028916

85973_at

A_14_P128472

A_23_P164718

A_24_P219757

A_24_P250333

A_24_P250335

GE59682

GO:0000398

GO:0003676

GO:0003677

GO:0003723

GO:0005515

GO:0005634

GO:0005654

GO:0005681

GO:0005685

GO:0006397

GO:0008380

GO:0016071

GO:0030619

GO:0042802

GO:0046540

GO:0097525

GO:1990446

GO:1990904

ILMN_1779399

M60784_s_at

PH_hs_0010385

PH_hs_0035642

TC19000567.hg

g4759155_3p_at

Participates

as a component of

U1 snRNP [nucleoplasm] (Homo sapiens)

Inferred To

Snrpa [nucleoplasm] (Mus musculus)

Snrpa [nucleoplasm] (Rattus norvegicus)

snf [nucleoplasm] (Drosophila melanogaster)

SNRPA [nucleoplasm] (Bos taurus)

SNRPA [nucleoplasm] (Canis familiaris)

SNRPA [nucleoplasm] (Plasmodium falciparum)

SNRPA [nucleoplasm] (Sus scrofa)

Ghost homologue of SNRPA [nucleoplasm] (Gallus gallus)

MUD1 [nucleoplasm] (Saccharomyces cerevisiae)

snrpa [nucleoplasm] (Danio rerio)

snrpa [nucleoplasm] (Xenopus tropicalis)

snrpb2 [nucleoplasm] (Dictyostelium discoideum)

usp102 [nucleoplasm] (Schizosaccharomyces pombe)

rnp-2 [nucleoplasm] (Caenorhabditis elegans)

Homologues of SNRPA [nucleoplasm] (Sus scrofa)

Cross References

RefSeq

NP_004587.1

OpenTargets

ENSG00000077312

ENSEMBL

ENSG00000077312, ENST00000243563, ENSP00000243563

HPA

ENSG00000077312-SNRPA

GeneCards

SNRPA

PRO

P09012

Pharos - Targets

P09012

GlyGen

P09012

PDB

1VC0, 5DDO, 1OIA, 6SR7, 6XH0, 4W90, 3EGZ, 6QX9, 3IWN, 5DDR, 3UD4, 1SJ4, 3BO4, 7B0Y, 1M5V, 3R1H, 1SJF, 1VBZ, 1VBX, 1NU4, 3L3C, 7DLZ, 2A3J, 8GXB, 1FHT, 1URN, 1U6B, 3IRW, 6LAS, 3G96, 3MUM, 7VPX, 3IIN, 7QR3, 8JY0, 1AUD, 7AEP, 2OIH, 3G9C, 1DZ5, 2NZ4, 1M5P, 3R1L, 6SQT, 2U1A, 3MXH, 3BO2, 5DDP, 7LHX, 6XH1, 1VC5, 3UD3, 4PRF, 6SQV, 6XH2, 4W92, 6XH3, 1SJ3, 4C4W, 3UCU, 3BO3, 5DDQ, 7DWH, 1VC6, 1VBY, 9QEQ, 7D7V, 3CUN, 3MUT, 3HHN, 3G8T, 8GXC, 6SQN, 3K0J, 6SQQ, 3MUV, 5FJ4, 6LAU, 1DRZ, 3CUL, 1ZZN, 7QR4, 6LAX, 4YB1, 3MUR, 3PGW, 6LAZ, 3G8S, 4PR6, 1M5O, 2OJ3, 3P49, 1M5K, 3UCZ

Interactors (22)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P09661 SNRPA1	1	SNRPA1 [nucleoplasm] (R-HSA-71958)	0.831	10
UniProt:P26599 PTBP1	1	PTBP1 [nucleoplasm] (R-HSA-71923)	0.8	7
UniProt:P61978 HNRNPK	2	HNRNPK [nucleoplasm] (R-HSA-71945) polySUMO2-K422-HNRNPK [nucleoplasm] (R-HSA-4570532)	0.743	5
UniProt:P62304 SNRPE	2	SNRPE [cytosol] (R-HSA-191782) SNRPE [nucleoplasm] (R-HSA-71905)	0.725	6
UniProt:P14373 TRIM27	2	TRIM27 [cytosol] (R-HSA-8851002) TRIM27 [nucleoplasm] (R-HSA-2997690)	0.718	6
UniProt:Q9BU61 NDUFAF3	1	NDUFAF3 [mitochondrial inner membrane] (R-HSA-5689126)	0.718	6
UniProt:P26368 U2AF2	2	U2AF2 [nucleoplasm] (R-HSA-71987) 5OHK15,276-U2AF2 [nucleoplasm] (R-HSA-9630011)	0.703	5
UniProt:P23246 SFPQ	3	SFPQ [nucleoplasm] (R-HSA-3900138) p-Y-SFPQ [nucleoplasm] (R-HSA-8849461) SFPQ [cytosol] (R-HSA-9635505)	0.688	5
UniProt:Q13838 DDX39B	2	DDX39B [nucleoplasm] (R-HSA-8849139) DDX39B [cytosol] (R-HSA-9715154)	0.666	4
UniProt:P62306 SNRPF	2	SNRPF [cytosol] (R-HSA-191852) SNRPF [nucleoplasm] (R-HSA-71907)	0.643	5
UniProt:Q00839 HNRNPU	1	HNRNPU [nucleoplasm] (R-HSA-71953)	0.564	2
UniProt:Q15366 PCBP2	2	PCBP2 [cytosol] (R-HSA-983457) PCBP2 [nucleoplasm] (R-HSA-71921)	0.556	3
UniProt:O00560 SDCBP	3	SDCBP [cytosol] (R-HSA-373639) SDCBP [azurophil granule lumen] (R-HSA-6799372) SDCBP [extracellular region] (R-HSA-6806206)	0.556	3
UniProt:Q9BTD8 RBM42	1	RBM42 [nucleoplasm] (R-HSA-9769526)	0.547	2
UniProt:P52298 NCBP2	2	NCBP2 [nucleoplasm] (R-HSA-51463) NCBP2 [cytosol] (R-HSA-162458)	0.527	2
UniProt:Q09161 NCBP1	2	NCBP1 [nucleoplasm] (R-HSA-51469) NCBP1 [cytosol] (R-HSA-162459)	0.527	2
UniProt:Q86VM9 ZC3H18	1	ZC3H18 [nucleoplasm] (R-HSA-9930040)	0.527	2
UniProt:P62318 SNRPD3	3	2xMe-SNRPD3 [cytosol] (R-HSA-191781) SNRPD3 [nucleoplasm] (R-HSA-71903) 2xMe-SNRPD3 [nucleoplasm] (R-HSA-192219)	0.527	2
UniProt:P14678 SNRPB	4	2xMe-SNRPB [cytosol] (R-HSA-192218) SNRPB [cytosol] (R-HSA-191798) SNRPB [nucleoplasm] (R-HSA-71896) Me2-R108,R112-SNRPB [nucleoplasm] (R-HSA-192213)	0.527	3
UniProt:P07910 HNRNPC	3	HNRNPC [nucleoplasm] (R-HSA-71933) SUMO1-K250-HNRNPC [nucleoplasm] (R-HSA-4570543) HNRNPC [cytosol] (R-HSA-9715136)	0.483	2
UniProt:Q9NR30 DDX21	1	DDX21 [nucleoplasm] (R-HSA-5250652)	0.483	2
UniProt:O75152 ZC3H11A	1	ZC3H11A [nucleoplasm] (R-HSA-8850659)	0.483	2

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