p-S5(CTD)-POLR2A [nucleoplasm]

Stable Identifier
R-HSA-77100
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
RNA Pol II (Ser5 phosphorylated) largest subunit, DNA-directed RNA polymerase II largest subunit , RPB1
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:P24928 POLR2A
Gene Names
POLR2A, POLR2
Chain
chain:1-1970
Reference Genes
BioGPS Gene:5430 POLR2A
COSMIC (genes):POLR2A POLR2A
CTD Gene:5430 POLR2A
dbSNP Gene:5430 POLR2A
ENSEMBL:ENSG00000181222 POLR2A
HGNC:9187 POLR2A
KEGG:hsa:5430 POLR2A
Monarch:5430 POLR2A
NCBI Gene:5430 POLR2A
OMIM:180660 POLR2A
UCSC:P24928 POLR2A
Reference Transcript
Participates
as a component of
Other forms of this molecule
POLR2A [nucleoplasm]
p-S2,S5(CTD)-POLR2A [nucleoplasm]
p-3S-POLR2A [nucleoplasm]
Ub,p-S2,S5(CTD)-POLR2A [nucleoplasm]
p-S5,S7(CTD)-POLR2A [nucleoplasm]
p-S2,S7(CTD)-POLR2A [nucleoplasm]
Inferred To
phospho-POLR2A [nucleoplasm] (Canis familiaris)
phospho-POLR2A [nucleoplasm] (Sus scrofa)
phospho-Polr2a [nucleoplasm] (Rattus norvegicus)
phospho-p-S5(CTD)-POLR2A [nucleoplasm] (Bos taurus)
phospho-p-S5(CTD)-POLR2A [nucleoplasm] (Caenorhabditis elegans)
phospho-p-S5(CTD)-POLR2A [nucleoplasm] (Dictyostelium discoideum)
phospho-p-S5(CTD)-POLR2A [nucleoplasm] (Drosophila melanogaster)
phospho-p-S5(CTD)-POLR2A [nucleoplasm] (Mus musculus)
phospho-p-S5(CTD)-POLR2A [nucleoplasm] (Plasmodium falciparum)
phospho-p-S5(CTD)-POLR2A [nucleoplasm] (Saccharomyces cerevisiae)
phospho-p-S5(CTD)-POLR2A [nucleoplasm] (Schizosaccharomyces pombe)
Ghost homologue of p-S5(CTD)-POLR2A [nucleoplasm] (Danio rerio)
Ghost homologue of p-S5(CTD)-POLR2A [nucleoplasm] (Gallus gallus)
Ghost homologue of p-S5(CTD)-POLR2A [nucleoplasm] (Xenopus tropicalis)
Modified Residues
Name
O-phospho-L-serine at 1843
Coordinate
1843
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1850
Coordinate
1850
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1857
Coordinate
1857
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1864
Coordinate
1864
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1871
Coordinate
1871
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1878
Coordinate
1878
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1892
Coordinate
1892
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1899
Coordinate
1899
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1906
Coordinate
1906
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1913
Coordinate
1913
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1920
Coordinate
1920
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1927
Coordinate
1927
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1934
Coordinate
1934
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
OpenTargets
PRO
Pharos - Targets
GlyGen
HMDB Protein
PDB
Interactors (21)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:O00267 SUPT5H  1 0.836 6
 UniProt:P19388 POLR2E  2 0.793 7
 UniProt:Q6P1J9 CDC73  1 0.708 6
 UniProt:P23193 TCEA1  1 0.708 5
 UniProt:P61218 POLR2F  2 0.643 5
 UniProt:Q8IXW5 RPAP2  1 0.643 4
 UniProt:Q9UBK9 UXT  1 0.643 3
 UniProt:P17844 DDX5  4 0.641 3
 UniProt:Q9Y5B0 CTDP1  1 0.564 2
 UniProt:O14744 PRMT5  3 0.558 6
 UniProt:Q9H3P2 NELFA  1 0.527 2
 UniProt:O95402 MED26  1 0.527 8
 UniProt:O00308 WWP2  1 0.527 3
 UniProt:P25963 NFKBIA  9 0.527 2
 UniProt:Q08945 SSRP1  1 0.527 2
 UniProt:Q9Y3C7 MED31  1 0.527 2
 UniProt:P01106 MYC  2 0.527 4
 UniProt:Q9BTT4 MED10  1 0.527 3
 UniProt:Q03468 ERCC6  2 0.499 2
 UniProt:Q9NPJ6 MED4  1 0.483 2
 UniProt:Q9H944 MED20  1 0.483 2
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