Reactome | RPN6 [secretory granule lumen]

RPN6 [secretory granule lumen]

Stable Identifier

R-SCE-6800943

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

secretory granule lumen

Synonyms

PSMD11, Q12377

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q12377

Gene Names

RPN6

Reference Genes

BioGPS Gene:851461 RPN6

ENSEMBL:YDL097C

KEGG:sce:YDL097C RPN6

Monarch:851461 RPN6

NCBI Gene:851461 RPN6

SGD:YDL097C

UCSC:Q12377 RPN6

Reference Transcript

RefSeq:NM_001180156.1 RPN6

Other Identifiers

1779716_at

6589_at

851461

GO:0000502

GO:0003674

GO:0005198

GO:0005515

GO:0005575

GO:0005737

GO:0006511

GO:0008150

GO:0008541

GO:0034515

GO:0042221

GO:0043161

GO:0043248

GO:0046686

GO:0051603

Participates

as a member of

Secretory granule lumen proteins [secretory granule lumen] (Saccharomyces cerevisiae)

Other forms of this molecule

RPN6 [cytosol]

RPN6 [ficolin-1-rich granule lumen]

RPN6 [extracellular region]

Inferred From

PSMD11 [secretory granule lumen] (Homo sapiens)

Cross References

RefSeq

NP_010186.1

ENSEMBL

YDL097C, YDL097C, YDL097C_mRNA

PRO

Q12377

PDB

3JCK, 7QO3, 5A5B, 6FVX, 6FVY, 6FVV, 6FVW, 6FVT, 6FVU, 5WVK, 6J2X, 6J2Q, 4CR2, 5WVI, 7QO5, 5MPC, 4CR4, 5MPB, 6J2C, 3JCP, 6J2N, 3JCO, 4CR3, 6J30, 5MPD, 5MPE, 3J47

Interactors (28)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q12250	4	RPN5 [cytosol] (R-SCE-68792) RPN5 [ficolin-1-rich granule lumen] (R-SCE-6800416) RPN5 [extracellular region] (R-SCE-6806480) RPN5 [secretory granule lumen] (R-SCE-6800934)	0.922	35
UniProt:Q08723	4	RPN8 [cytosol] (R-SCE-68806) RPN8 [ficolin-1-rich granule lumen] (R-SCE-6800406) RPN8 [extracellular region] (R-SCE-6806488) RPN8 [secretory granule lumen] (R-SCE-6801008)	0.818	31
UniProt:Q04062	4	RPN9 [cytosol] (R-SCE-68794) RPN9 [ficolin-1-rich granule lumen] (R-SCE-6800413) RPN9 [extracellular region] (R-SCE-6806469) RPN9 [secretory granule lumen] (R-SCE-6800983)	0.818	22
UniProt:P38764	4	RPN1 [cytosol] (R-SCE-68796) RPN1 [ficolin-1-rich granule lumen] (R-SCE-6800435) RPN1 [extracellular region] (R-SCE-6806479) RPN1 [secretory granule lumen] (R-SCE-6800919)	0.813	29
UniProt:P38886 RPN10			0.813	14
UniProt:Q06103	4	RPN7 [cytosol] (R-SCE-68804) RPN7 [ficolin-1-rich granule lumen] (R-SCE-6800440) RPN7 [extracellular region] (R-SCE-6806486) RPN7 [secretory granule lumen] (R-SCE-6801036)	0.813	23
UniProt:Q01939	1	PSMC5 [cytosol] (R-SCE-68780)	0.758	14
UniProt:P33299	4	PSMC2 [cytosol] (R-SCE-68771) PSMC2 [ficolin-1-rich granule lumen] (R-SCE-6800421) PSMC2 [extracellular region] (R-SCE-6806472) PSMC2 [secretory granule lumen] (R-SCE-6800994)	0.758	23
UniProt:P43588	4	PSMD14 [cytosol] (R-SCE-68722) PSMD14 [ficolin-1-rich granule lumen] (R-SCE-6800419) PSMD14 [extracellular region] (R-SCE-6806511) PSMD14 [secretory granule lumen] (R-SCE-6800926)	0.758	25
UniProt:P53549	1	PSMC6 [cytosol] (R-SCE-68783)	0.745	12
UniProt:P33298	1	PSMC4 [cytosol] (R-SCE-68777)	0.744	15
UniProt:P50086 PSD10			0.723	6
UniProt:P53196 RPN14			0.708	4
UniProt:P38737 ECM29			0.69	4
UniProt:P38348 HSM3			0.688	3
UniProt:P43593	1	UBP6 [cytosol] (R-SCE-5689541)	0.669	15
UniProt:P33297	4	PSMC3 [cytosol] (R-SCE-68774) PSMC3 [ficolin-1-rich granule lumen] (R-SCE-6800429) PSMC3 [extracellular region] (R-SCE-6806496) PSMC3 [secretory granule lumen] (R-SCE-6800917)	0.669	14
UniProt:P32496	1	RPN12 [cytosol] (R-SCE-68808)	0.669	12
UniProt:P32565	3	RPN2 [cytosol] (R-SCE-68786) RPN2 [azurophil granule lumen] (R-SCE-6798741) RPN2 [extracellular region] (R-SCE-6806194)	0.669	17
UniProt:P40327	1	PSMC1 [cytosol] (R-SCE-68768)	0.669	12
UniProt:O13563 RPN13			0.669	6
UniProt:P40016	4	RPN3 [cytosol] (R-SCE-68798) RPN3 [ficolin-1-rich granule lumen] (R-SCE-6800408) RPN3 [extracellular region] (R-SCE-6806443) RPN3 [secretory granule lumen] (R-SCE-6800873)	0.669	19
UniProt:O94742 SEM1			0.564	12
UniProt:P10592	20	SSA2 [cytosol] (R-SCE-264476) SSA2 [nucleoplasm] (R-SCE-5082380) SSA2 [cytosol] (R-SCE-3371410-3) SSA2 [cytosol] (R-SCE-3371408-3) SSA2 [cytosol] (R-SCE-6792602-3) SSA2 [ficolin-1-rich granule lumen] (R-SCE-6801512-3) SSA2 [ficolin-1-rich granule lumen] (R-SCE-6801496-3) SSA2 [ficolin-1-rich granule lumen] (R-SCE-6801494) SSA2 [extracellular region] (R-SCE-6805872-3) SSA2 [extracellular region] (R-SCE-6806500-3) SSA2 [extracellular region] (R-SCE-6805936) SSA2 [secretory granule lumen] (R-SCE-6801530) SSA2 [secretory granule lumen] (R-SCE-6801472-3) SSA2 [nucleoplasm] (R-SCE-6792605-3) SSA2 [nucleoplasm] (R-SCE-912480-3) SSA2 [nucleoplasm] (R-SCE-5082367-3) SSA2 [nucleoplasm] (R-SCE-5252082-3) SSA2 [nucleoplasm] (R-SCE-5252088-3) SSA2 [nucleoplasm] (R-SCE-5252009-3) SSA2 [cytosol] (R-SCE-5251948-3)	0.527	2
UniProt:P32628	2	RAD23 [nucleoplasm] (R-SCE-62590) RAD23 [nucleoplasm] (R-SCE-5688076)	0.527	2
UniProt:P11484	17	HSPA1L [cytosol] (R-SCE-3371410-4) HSPA2 [cytosol] (R-SCE-3371408-4) HSPA1A [cytosol] (R-SCE-6792602-4) HSPA6 [ficolin-1-rich granule lumen] (R-SCE-6801512-4) HSPA1A [ficolin-1-rich granule lumen] (R-SCE-6801496-4) HSPA1A [extracellular region] (R-SCE-6805872-4) HSPA6 [extracellular region] (R-SCE-6806500-4) HSPA6 [secretory granule lumen] (R-SCE-6801472-4) HSPA1A [nucleoplasm] (R-SCE-6792605-4) HSPA2 [nucleoplasm] (R-SCE-912480-4) HSPA1L [nucleoplasm] (R-SCE-5082367-4) HSPA14 [nucleoplasm] (R-SCE-5252082-4) HSPA6 [nucleoplasm] (R-SCE-5252088-4) HSPA13 [nucleoplasm] (R-SCE-5252009-4) HSPA14 [cytosol] (R-SCE-5251948-4) HSPA13 [cytosol] (R-SCE-5251981-4) HSPA6 [cytosol] (R-SCE-3371521-4)	0.527	2
UniProt:P10591	17	SSA1 [cytosol] (R-SCE-3371410-2) SSA1 [cytosol] (R-SCE-3371408-2) SSA1 [cytosol] (R-SCE-6792602-2) SSA1 [ficolin-1-rich granule lumen] (R-SCE-6801512-2) SSA1 [ficolin-1-rich granule lumen] (R-SCE-6801496-2) SSA1 [extracellular region] (R-SCE-6805872-2) SSA1 [extracellular region] (R-SCE-6806500-2) SSA1 [secretory granule lumen] (R-SCE-6801472-2) SSA1 [nucleoplasm] (R-SCE-6792605-2) SSA1 [nucleoplasm] (R-SCE-912480-2) SSA1 [nucleoplasm] (R-SCE-5082367-2) SSA1 [nucleoplasm] (R-SCE-5252082-2) SSA1 [nucleoplasm] (R-SCE-5252088-2) SSA1 [nucleoplasm] (R-SCE-5252009-2) SSA1 [cytosol] (R-SCE-5251948-2) SSA1 [cytosol] (R-SCE-5251981-2) SSA1 [cytosol] (R-SCE-3371521-2)	0.527	2
UniProt:P40303	1	PRE6 [cytosol] (R-SCE-68736)	0.527	2