Reactome | RNPS1 [nucleoplasm]

RNPS1 [nucleoplasm]

Stable Identifier

R-HSA-156778

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Locations in the PathwayBrowser

Expand all

Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Viral Infection Pathways (Homo sapiens)
    - Dengue Virus Infection (Homo sapiens)
      - Dengue Virus-Host Interactions (Homo sapiens)
        
        NS5 interacts with Spliceosome (Homo sapiens)
        
        NS5:Spliceosomal Intermediate C Complex [nucleoplasm] (Homo sapiens)
        
        Spliceosomal Intermediate C Complex [nucleoplasm] (Homo sapiens)
        
        RNPS1 [nucleoplasm] (Homo sapiens)
        
        Spliceosomal Intermediate C Complex [nucleoplasm] (Homo sapiens)
        
        RNPS1 [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q15287 RNPS1

Gene Names

RNPS1, LDC2

Chain

chain:1-305

Reference Genes

BioGPS Gene:10921 RNPS1

COSMIC - genes:RNPS1 RNPS1

CTD Gene:10921 RNPS1

dbSNP Gene:10921 RNPS1

ENSEMBL:ENSG00000205937 RNPS1

HGNC:10080 RNPS1

KEGG:hsa:10921 RNPS1

Monarch:10921 RNPS1

NCBI Gene:10921 RNPS1

OMIM:606447 RNPS1

UCSC:Q15287 RNPS1

Reference Transcript

Participates

as a component of

Other forms of this molecule

RNPS1 [cytosol]

Inferred To

rns1 [nucleoplasm] (Schizosaccharomyces pombe)

RnpS1 [nucleoplasm] (Drosophila melanogaster)

Ghost homologue of RNPS1 [nucleoplasm] (Xenopus tropicalis)

rnp-5 [nucleoplasm] (Caenorhabditis elegans)

Rnps1 [nucleoplasm] (Mus musculus)

Rnps1 [nucleoplasm] (Rattus norvegicus)

RNPS1 [nucleoplasm] (Bos taurus)

RNPS1 [nucleoplasm] (Canis familiaris)

RNPS1 [nucleoplasm] (Dictyostelium discoideum)

RNPS1 [nucleoplasm] (Gallus gallus)

RNPS1 [nucleoplasm] (Sus scrofa)

rnps1 [nucleoplasm] (Danio rerio)

Cross References

RefSeq

NP_006702.1, XP_054235386.1, XP_054235388.1, XP_005255106.1, NP_001273556.1, XP_047289472.1, NP_001273554.1, XP_005255105.1, XP_054235387.1, NP_542161.1, NP_001273555.1

OpenTargets

ENSG00000205937

ENSEMBL

ENSP00000457723, ENSP00000457820, ENSP00000301730, ENST00000565678, ENSP00000456352, ENSG00000205937, ENST00000397086, ENSP00000315859, ENST00000568631, ENST00000566458, ENST00000301730, ENST00000320225, ENSP00000380275

GeneCards

RNPS1

HPA

ENSG00000205937-RNPS1

PRO

Q15287

Pharos - Targets

Q15287

GlyGen

Q15287

PDB

4A8X

Interactors (52)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q08170 SRSF4	1	SRSF4 [nucleoplasm] (R-HSA-72024)	0.752	4
UniProt:Q13523 PRP4K	1	PRPF4B [nucleoplasm] (R-HSA-9769525)	0.744	5
UniProt:P26368 U2AF2	2	U2AF2 [nucleoplasm] (R-HSA-71987) 5OHK15,276-U2AF2 [nucleoplasm] (R-HSA-9630011)	0.744	6
UniProt:P68400 CSNK2A1	2	CSNK2A1 [cytosol] (R-HSA-201713) CSNK2A1 [nucleoplasm] (R-HSA-6805057)	0.669	4
UniProt:O94906 PRPF6	1	PRPF6 [nucleoplasm] (R-HSA-71881)	0.669	3
UniProt:Q9C0J8 WDR33	1	WDR33 [nucleoplasm] (R-HSA-8938784)	0.669	3
UniProt:Q8N5F7 NKAP	1	NKAP [nucleoplasm] (R-HSA-9769602)	0.669	4
UniProt:Q8IYB3 SRRM1	2	SRRM1 [cytosol] (R-HSA-159255) SRRM1 [nucleoplasm] (R-HSA-156781)	0.669	3
UniProt:O75400 PRPF40A	1	PRPF40A [nucleoplasm] (R-HSA-8867890)	0.669	3
UniProt:Q13427 PPIG	2	PPIG [nucleoplasm] (R-HSA-9769592) PPIG [cytosol] (R-HSA-9728768)	0.669	4
UniProt:Q05519 SRSF11	1	SRSF11 [nucleoplasm] (R-HSA-72058)	0.669	3
UniProt:Q16629 SRSF7	1	SRSF7 [nucleoplasm] (R-HSA-72029)	0.666	4
UniProt:Q07955 SRSF1	1	SRSF1 [nucleoplasm] (R-HSA-72031)	0.665	3
UniProt:Q9UKV3 ACIN1	4	ACIN1 [cytosol] (R-HSA-212519) ACIN1(1094-1341) [cytosol] (R-HSA-212516) ACIN1(1-1093) [cytosol] (R-HSA-212520) ACIN1 [nucleoplasm] (R-HSA-9770238)	0.659	4
UniProt:Q9BZI7 UPF3B	2	UPF3B [nucleoplasm] (R-HSA-156776) UPF3B [cytosol] (R-HSA-159258)	0.643	3
UniProt:Q7Z6E9 RBBP6	2	RBBP6 [cytosol] (R-HSA-8850895) RBBP6 [nucleoplasm] (R-HSA-9970176)	0.643	5
UniProt:Q9UER7 DAXX	13	DAXX [nucleoplasm] (R-HSA-3222068) DAXX A36Qfs108 [nucleoplasm] (R-HSA-9673105) DAXX K56 [nucleoplasm] (R-HSA-9673089) DAXX A103Sfs40 [nucleoplasm] (R-HSA-9673121) DAXX C106 [nucleoplasm] (R-HSA-9673079) DAXX E72Nfs72 [nucleoplasm] (R-HSA-9673110) DAXX E104 [nucleoplasm] (R-HSA-9673078) DAXX H26Tfs118 [nucleoplasm] (R-HSA-9673114) DAXX S138 [nucleoplasm] (R-HSA-9673081) DAXX C74* [nucleoplasm] (R-HSA-9673096) DAXX R48Vfs93 [nucleoplasm] (R-HSA-9673103) DAXX L98Vfs13 [nucleoplasm] (R-HSA-9673102) monoSUMO1-K630,K631-DAXX [nucleoplasm] (R-HSA-4086086)	0.643	4
UniProt:Q14160 SCRIB	1	SCRIB [cytosol] (R-HSA-4608858)	0.643	4
UniProt:Q14562 DHX8	1	DHX8 [nucleoplasm] (R-HSA-5688092)	0.643	4
UniProt:Q9Y2W1 THRAP3	1	THRAP3 [nucleoplasm] (R-HSA-8932115)	0.589	2
UniProt:P61981 YWHAG	1	YWHAG [cytosol] (R-HSA-380312)	0.589	2
UniProt:O43809 NUDT21	1	NUDT21 [nucleoplasm] (R-HSA-72010)	0.564	2
UniProt:O43290 SART1	1	SART1 [nucleoplasm] (R-HSA-4615999)	0.564	2
UniProt:Q92620 DHX38	1	DHX38 [nucleoplasm] (R-HSA-72060)	0.564	2
UniProt:O43464 HTRA2	1	HTRA2 [mitochondrial intermembrane space] (R-HSA-56655)	0.564	2
UniProt:Q9P2I0 CPSF2	1	CPSF2 [nucleoplasm] (R-HSA-71991)	0.564	2
UniProt:Q9UQ35 SRRM2	1	SRRM2 [nucleoplasm] (R-HSA-8865888)	0.564	2
UniProt:O95232 LUC7L3	1	LUC7L3 [nucleoplasm] (R-HSA-9770258)	0.564	2
UniProt:O75533 SF3B1	1	SF3B1 [nucleoplasm] (R-HSA-71968)	0.564	3
UniProt:Q9BUQ8 DDX23	1	DDX23 [nucleoplasm] (R-HSA-71879)	0.564	2
UniProt:Q9UJV9 DDX41	4	DDX41 [cytosol] (R-HSA-3134807) K48polyUb-DDX41 [cytosol] (R-HSA-3134942) K48polyUb-DDX41 [cytosol] (R-HSA-3134941) DDX41 [nucleoplasm] (R-HSA-9769601)	0.564	2
UniProt:P67870 CSNK2B	5	CSNK2B [cytosol] (R-HSA-201693) CSNK2B [nucleoplasm] (R-HSA-6805067) CSNK2B [ficolin-1-rich granule lumen] (R-HSA-6801290) CSNK2B [extracellular region] (R-HSA-6806508) CSNK2B [secretory granule lumen] (R-HSA-6801319)	0.564	2
UniProt:Q9BTD8 RBM42	1	RBM42 [nucleoplasm] (R-HSA-9769526)	0.564	2
UniProt:P38919 EIF4A3	2	EIF4A3 [cytosol] (R-HSA-927868) EIF4A3 [nucleoplasm] (R-HSA-8849149)	0.558	4
UniProt:Q9NRD5 PICK1	2	PICK1 [endocytic vesicle membrane] (R-HSA-417017) PICK1 [plasma membrane] (R-HSA-416989)	0.556	3
UniProt:Q96MU7 YTHDC1	1	YTHDC1 [nucleoplasm] (R-HSA-9935812)	0.556	3
UniProt:Q9UGI0 ZRANB1	1	ZRANB1 [cytosol] (R-HSA-6781939)	0.556	3
UniProt:Q13242 SRSF9	1	SRSF9 [nucleoplasm] (R-HSA-72037)	0.556	3
UniProt:P84103 SRSF3	1	SRSF3 [nucleoplasm] (R-HSA-72035)	0.556	3
UniProt:Q13247 SRSF6	1	SRSF6 [nucleoplasm] (R-HSA-72026)	0.547	3
UniProt:Q15811 ITSN1	1	ITSN1 [cytosol] (R-HSA-3006481)	0.527	2
UniProt:Q9BYW2 SETD2	1	SETD2 [nucleoplasm] (R-HSA-1183220)	0.527	3
UniProt:P07910 HNRNPC	3	HNRNPC [nucleoplasm] (R-HSA-71933) SUMO1-K250-HNRNPC [nucleoplasm] (R-HSA-4570543) HNRNPC [cytosol] (R-HSA-9715136)	0.527	3
UniProt:P49756 RBM25	1	RBM25 [nucleoplasm] (R-HSA-9770250)	0.527	2
UniProt:O15234 CASC3	2	CASC3 [cytosol] (R-HSA-927807) CASC3 [nucleoplasm] (R-HSA-8849148)	0.527	3
UniProt:P09661 SNRPA1	1	SNRPA1 [nucleoplasm] (R-HSA-71958)	0.527	2
UniProt:Q9H4G0 EPB41L1	2	EPB41L1 [cytosol] (R-HSA-392241) EPB41L1 [plasma membrane] (R-HSA-416333)	0.527	3
UniProt:O94887 FARP2	2	p-Y-FARP2 [cytosol] (R-HSA-9968470) FARP2 [cytosol] (R-HSA-396935)	0.527	2
UniProt:Q9UBC2 EPS15L1	2	EPS15L1 [plasma membrane] (R-HSA-182937) EPS15L1 [cytosol] (R-HSA-8935900)	0.527	2
UniProt:Q96D71 REPS1	1	REPS1 [cytosol] (R-HSA-8862265)	0.527	2
UniProt:P42566 EPS15	2	EPS15 [cytosol] (R-HSA-182920) p-Y849 EPS15 [cytosol] (R-HSA-8867028)	0.527	2
UniProt:O75152 ZC3H11A	1	ZC3H11A [nucleoplasm] (R-HSA-8850659)	0.483	2

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