Reactome | TECR [endoplasmic reticulum membrane]

TECR [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-548663

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

Trans-2,3-enoyl-CoA reductase

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9NZ01 TECR

Gene Names

TECR, GPSN2, SC2

Chain

chain:1-308

Reference Genes

BioGPS Gene:9524 TECR

COSMIC (genes):TECR TECR

CTD Gene:9524 TECR

dbSNP Gene:9524 TECR

ENSEMBL:ENSG00000099797 TECR

HGNC:4551 TECR

KEGG Gene (Homo sapiens):9524 TECR

Monarch:9524 TECR

NCBI Gene:9524 TECR

OMIM:610057 TECR

UCSC:Q9NZ01 TECR

Reference Transcript

Other Identifiers

0002480168

0002970053

11730198_s_at

11755502_x_at

16859018

208336_s_at

2776902

2776903

2776904

2776905

2776906

2776907

2776908

3822811

3822812

3822825

3822828

3822830

3822832

3822834

3822836

3822838

3822840

3822842

3822844

3822845

3822846

3822847

3822848

38966_at

8026341

8101622

9524

A_23_P56339

A_33_P3372466

GE81450

GO:0003674

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005737

GO:0005783

GO:0005789

GO:0006629

GO:0006631

GO:0006633

GO:0006665

GO:0006790

GO:0008150

GO:0009058

GO:0016020

GO:0016021

GO:0016491

GO:0016627

GO:0030176

GO:0030497

GO:0034641

GO:0035338

GO:0042761

GO:0043226

GO:0044281

GO:0051186

GO:0055114

GO:0102758

ILMN_1720799

ILMN_3310514

PH_hs_0015721

TC04001361.hg

TC19000259.hg

TC19002003.hg

g4759061_3p_s_at

Participant Of

hasMember

TECR,TECRL [endoplasmic reticulum membrane]

Inferred To

tecrb [endoplasmic reticulum membrane] (Danio rerio)

art-1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)

tecr [endoplasmic reticulum membrane] (Xenopus tropicalis)

TECR [endoplasmic reticulum membrane] (Canis familiaris)

TECR [endoplasmic reticulum membrane] (Plasmodium falciparum)

TECR [endoplasmic reticulum membrane] (Schizosaccharomyces pombe)

TECR [endoplasmic reticulum membrane] (Sus scrofa)

Sc2 [endoplasmic reticulum membrane] (Drosophila melanogaster)

gpsn2 [endoplasmic reticulum membrane] (Dictyostelium discoideum)

Tecr [endoplasmic reticulum membrane] (Mus musculus)

Tecr [endoplasmic reticulum membrane] (Rattus norvegicus)

TSC13 [endoplasmic reticulum membrane] (Saccharomyces cerevisiae)

Cross References

RefSeq

NP_612510.1, NP_001308099.1

OpenTargets

ENSG00000099797

GeneCards

Q9NZ01

HPA

ENSG00000099797-TECR

Ensembl

ENSG00000099797, ENST00000215567, ENSP00000215567

PRO

Q9NZ01

Orphanet

20141

PDB

2DZJ

HMDB Protein

HMDBP09218

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q3KNW5 SLC10A6	1	SLC10A6 [plasma membrane] (R-HSA-433091)	0.556	3
UniProt:Q8N4V1 MMGT1	1	MMGT1 [Golgi membrane] (R-HSA-5216137)	0.556	3
UniProt:Q86WV6 STING1	5	K63polyUb-STING [cytoplasmic vesicle membrane] (R-HSA-3248021) K63polyUb-STING [endoplasmic reticulum membrane] (R-HSA-3134805) TMEM173 [endoplasmic reticulum membrane] (R-HSA-1834940) TMEM173 [plasma membrane] (R-HSA-6804815) TMEM173 [secretory granule membrane] (R-HSA-6804798)	0.556	3
UniProt:Q96BA8 CREB3L1	7	CREB3L1(427-519) [Golgi membrane] (R-HSA-8874139) CREB3L1 [Golgi membrane] (R-HSA-8874155) CREB3L1(1-426) [Golgi membrane] (R-HSA-8874153) CREB3L1 [endoplasmic reticulum membrane] (R-HSA-8874157) CREB3L1(1-375) [cytosol] (R-HSA-8874215) CREB3L1(376-426) [Golgi membrane] (R-HSA-8874213) CREB3L1(1-375) [nucleoplasm] (R-HSA-8874222)	0.556	3
UniProt:Q00059 TFAM	2	TFAM(1-246) [cytosol] (R-HSA-1592203) TFAM [mitochondrial matrix] (R-HSA-163312)	0.556	3
UniProt:O00501 CLDN5	2	CLDN5 [plasma membrane] (R-HSA-419991) CLDN5 [cell junction] (R-HSA-421264)	0.556	3
UniProt:Q3SXY8 ARL13B	7	PolyUb-Misfolded ARL13B [cytosol] (R-HSA-9641129) PolyUb-Misfolded ARL13B [lysosomal lumen] (R-HSA-9660004) Ub-Misfolded ARL13B [cytosol] (R-HSA-9641119) Misfolded ARL13B [cytosol] (R-HSA-9640110) Misfolded ARL13B [cilium] (R-HSA-9640116) ARL13B [cilium] (R-HSA-5618181) PolyUb-Misfolded ARL13B [late endosome lumen] (R-HSA-9659986)	0.556	3
UniProt:Q13418 ILK	1	ILK [cytosol] (R-HSA-432864)	0.527	2
UniProt:P27824 CANX	2	CANX [integral component of lumenal side of endoplasmic reticulum membrane] (R-HSA-983091) CANX [endoplasmic reticulum lumen] (R-HSA-195906)	0.462	2

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