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RASAL2 [cytosol]
Stable Identifier
R-HSA-5658224
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
MAPK family signaling cascades (Homo sapiens)
MAPK1/MAPK3 signaling (Homo sapiens)
RAF/MAP kinase cascade (Homo sapiens)
Regulation of RAS by GAPs (Homo sapiens)
RAS GAPs bind RAS:GTP (Homo sapiens)
RAS GAPs [cytosol] (Homo sapiens)
RASAL2 [cytosol] (Homo sapiens)
p21 RAS:GTP:RAS GAPs [plasma membrane] (Homo sapiens)
RAS GAPs [cytosol] (Homo sapiens)
RASAL2 [cytosol] (Homo sapiens)
RAS GAPs stimulate RAS GTPase activity (Homo sapiens)
RAS GAPs [cytosol] (Homo sapiens)
RASAL2 [cytosol] (Homo sapiens)
p21 RAS:GTP:RAS GAPs [plasma membrane] (Homo sapiens)
RAS GAPs [cytosol] (Homo sapiens)
RASAL2 [cytosol] (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
RND1 GTPase cycle (Homo sapiens)
RND1 binds effectors (Homo sapiens)
RND1 effectors [cytosol] (Homo sapiens)
RASAL2 [cytosol] (Homo sapiens)
RND1:GTP:RND1 effectors [plasma membrane] (Homo sapiens)
RND1 effectors [cytosol] (Homo sapiens)
RASAL2 [cytosol] (Homo sapiens)
RND3 GTPase cycle (Homo sapiens)
RND3 binds effectors (Homo sapiens)
RND3 effectors [cytosol] (Homo sapiens)
RASAL2 [cytosol] (Homo sapiens)
RND3:GTP:RND3 effectors [plasma membrane] (Homo sapiens)
RND3 effectors [cytosol] (Homo sapiens)
RASAL2 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9UJF2 RASAL2
Gene Names
RASAL2, NGAP
Chain
chain:1-1139
Reference Genes
BioGPS Gene:9462 RASAL2
COSMIC (genes):RASAL2 RASAL2
CTD Gene:9462 RASAL2
dbSNP Gene:9462 RASAL2
ENSEMBL:ENSG00000075391 RASAL2
ENSEMBL_homo_sapiens_GENE:ENSG00000075391.18 RASAL2
HGNC:9874 RASAL2
KEGG Gene (Homo sapiens):9462 RASAL2
Monarch:9462 RASAL2
NCBI Gene:9462 RASAL2
OMIM:606136 RASAL2
UCSC:Q9UJF2 RASAL2
Reference Transcript
RefSeq:NM_170692.2 RASAL2
RefSeq:NM_004841.3 RASAL2
Other Identifiers
11739803_a_at
11739804_s_at
11739805_a_at
11739806_a_at
11741409_s_at
1557506_PM_a_at
1557506_a_at
16674211
219026_PM_s_at
219026_s_at
222810_PM_s_at
222810_s_at
227036_PM_at
227036_at
234343_PM_s_at
234343_s_at
2369111
2369112
2369113
2369114
2369115
2369116
2369157
2369160
2369175
2369186
2369194
2369197
2369198
2369199
2369201
2369202
2369204
2369205
2369208
2369212
2369213
2369214
2369215
2369217
2369220
2369221
2369222
2369223
2369237
2369239
2369241
2369243
2369245
43872_at
47559_at
48413_at
49125_at
7907611
9462
A_14_P128242
A_23_P502747
A_24_P419250
A_33_P3350758
GE791743
GE821881
GO:0002021
GO:0005096
GO:0005515
GO:0005829
GO:0007165
GO:0009749
GO:0010467
GO:0023052
GO:0035264
GO:0043087
GO:0048856
GO:0051604
GO:0060612
GO:0098772
GO:2000257
HMNXSV003016283
HMNXSV003045101
Hs.227806.0.S1_3p_a_at
Hs.227806.1.S1_3p_a_at
Hs.29263.2.A1_3p_at
Hs2.25243.1.A1_3p_s_at
ILMN_1652952
ILMN_1673455
ILMN_1813701
PH_hs_0012663
TC01001539.hg
TC01004850.hg
g4758807_3p_a_at
p1282
Participates
as a candidate of
RND3 effectors [cytosol] (Homo sapiens)
RND1 effectors [cytosol] (Homo sapiens)
as a member of
RAS GAPs [cytosol] (Homo sapiens)
Inferred To
Rasal2 [cytosol]
(Mus musculus)
Rasal2 [cytosol]
(Rattus norvegicus)
gap-2 [cytosol]
(Caenorhabditis elegans)
IRA1 [cytosol]
(Saccharomyces cerevisiae)
raskol [cytosol]
(Drosophila melanogaster)
Homologues of RASAL2 [cytosol]
(Saccharomyces cerevisiae)
IRA2 [cytosol]
(Saccharomyces cerevisiae)
BUD2 [cytosol]
(Saccharomyces cerevisiae)
RASAL2 [cytosol]
(Bos taurus)
RASAL2 [cytosol]
(Canis familiaris)
RASAL2 [cytosol]
(Gallus gallus)
RASAL2 [cytosol]
(Sus scrofa)
Cross References
RefSeq
NP_733793.2
,
NP_004832.1
OpenTargets
ENSG00000075391
HPA
ENSG00000075391-RASAL2
GeneCards
Q9UJF2
Ensembl
ENSG00000075391
,
ENST00000462775
,
ENST00000367649
,
ENSP00000356621
,
ENSP00000420558
PRO
Q9UJF2
Pharos - Targets
Q9UJF2
Interactors (7)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P48729 CSNK1A1
2
CSNK1A1 [cytosol]
(R-HSA-195263)
CSNK1A1 [cilium]
(R-HSA-5632507)
0.725
4
UniProt:P31946 YWHAB
1
YWHAB [cytosol]
(R-HSA-48888)
0.706
5
UniProt:P49674 CSNK1E
2
CSNK1E [nucleoplasm]
(R-HSA-421306)
CSNK1E [cytosol]
(R-HSA-205877)
0.643
3
UniProt:P63104 YWHAZ
2
YWHAZ [nucleoplasm]
(R-HSA-450469)
YWHAZ [cytosol]
(R-HSA-206099)
0.615
3
UniProt:Q96PC5 MIA2
1
MIA2 [endoplasmic reticulum membrane]
(R-HSA-9637821)
0.556
3
UniProt:Q13077 TRAF1
3
TRAF1 [cytosol]
(R-HSA-5634163)
TRAF1(1-163) [cytosol]
(R-HSA-5634199)
TRAF1(164-416) [cytosol]
(R-HSA-5634204)
0.556
3
UniProt:P62258 YWHAE
1
YWHAE [cytosol]
(R-HSA-194368)
0.483
3
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