YES1 [cytosol]

Stable Identifier
R-HSA-373640
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Proto-oncogene tyrosine-protein kinase Yes
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:P07947 YES1
Gene Names
YES1, YES
Chain
initiator methionine:, chain:2-543
Reference Genes
BioGPS Gene:7525 YES1
COSMIC (genes):YES1 YES1
CTD Gene:7525 YES1
dbSNP Gene:7525 YES1
ENSEMBL:ENSG00000176105 YES1
ENSEMBL_homo_sapiens_GENE:ENSG00000176105.14 YES1
HGNC:12841 YES1
KEGG Gene (Homo sapiens):7525 YES1
Monarch:7525 YES1
NCBI Gene:7525 YES1
OMIM:164880 YES1
UCSC:P07947 YES1
Reference Transcript
Other Identifiers
11719415_a_at
1674_at
16853445
202932_PM_at
202932_at
202933_PM_s_at
202933_s_at
2521765
3795939
3795941
3795943
3795944
3795945
3795946
3795950
3795952
3795954
3795958
3795959
3795962
3795965
3795966
3795967
3795970
3795971
3795990
3795991
3795992
3795993
3795994
3795995
3795996
3940656
3940657
3940661
7525
8021984
A_23_P164507
A_24_P48403
GE62489
GO:0000166
GO:0001784
GO:0002376
GO:0002862
GO:0003013
GO:0003824
GO:0004672
GO:0004713
GO:0004715
GO:0005102
GO:0005515
GO:0005524
GO:0005576
GO:0005615
GO:0005737
GO:0005794
GO:0005813
GO:0005815
GO:0005829
GO:0005856
GO:0005884
GO:0005886
GO:0005925
GO:0006351
GO:0006355
GO:0006468
GO:0006954
GO:0007155
GO:0007169
GO:0010827
GO:0016020
GO:0016192
GO:0016301
GO:0016310
GO:0016740
GO:0019899
GO:0023052
GO:0030154
GO:0031234
GO:0031295
GO:0036120
GO:0036211
GO:0038096
GO:0043114
GO:0043226
GO:0044325
GO:0045087
GO:0045944
GO:0048013
GO:0048870
GO:0050731
GO:0050900
GO:0055085
GO:0070062
GO:0071300
GO:0071560
GO:0098542
GO:0140096
HMNXSV003042499
ILMN_1691466
M15990_at
PH_hs_0035676
TC18000278.hg
g4885660_3p_a_at
Participates
as a component of
as an input of
as a member of
as a candidate of
Other forms of this molecule
MyrG-p-Y426-YES1 [plasma membrane]
Inferred To
YES1 [cytosol] (Bos taurus)
YES1 [cytosol] (Caenorhabditis elegans)
YES1 [cytosol] (Canis familiaris)
YES1 [cytosol] (Danio rerio)
YES1 [cytosol] (Drosophila melanogaster)
YES1 [cytosol] (Gallus gallus)
YES1 [cytosol] (Mus musculus)
YES1 [cytosol] (Rattus norvegicus)
YES1 [cytosol] (Sus scrofa)
YES1 [cytosol] (Xenopus tropicalis)
Cross References
RefSeq
ZINC - World Drugs
Guide to Pharmacology - Targets
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC target
ZINC - Biogenic
PRO
PDB
ZINC - Investigational
HPA
GeneCards
Ensembl
Pharos - Targets
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (71)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q16543 CDC37  1 0.744 6
 UniProt:Q9BWW4 SSBP3      0.718 6
 UniProt:Q9NVV9 THAP1      0.718 6
 UniProt:Q12933 TRAF2  5 0.718 6
 UniProt:Q96BR9 ZBT8A      0.718 6
 UniProt:I6L996 I6L996      0.718 6
 UniProt:P51116 FXR2      0.718 6
 UniProt:O14543 SOCS3  1 0.718 6
 UniProt:Q9Y4K3 TRAF6  8 0.718 6
 UniProt:Q8IVP5 FUNDC1  4 0.666 4
 UniProt:P09769 FGR  3 0.643 4
 UniProt:P13569 CFTR  17 0.615 12
 UniProt:Q8TAK6 OLIG1      0.57 3
 UniProt:Q9H5V8 CDCP1      0.564 2
 UniProt:P00533 EGFR  20 0.564 3
 UniProt:P08238 HSP90AB1  6 0.564 3
 UniProt:Q9NR46 SHLB2      0.556 3
 UniProt:P51114-2 FXR1      0.556 3
 UniProt:Q96D03 DDT4L      0.556 3
 UniProt:P17661 DES  1 0.556 3
 UniProt:Q9H257-2 CARD9      0.556 3
 UniProt:Q92569 PIK3R3  2 0.556 3
 UniProt:Q9NUP9 LIN7C  2 0.556 3
 UniProt:Q13191 CBLB  1 0.556 3
 UniProt:P49023-2 PXN      0.556 3
 UniProt:Q9Y2J4 AMOTL2  1 0.556 3
 IntAct:EBI-16439879 CCSB ORF ID      0.556 3
 UniProt:P56945 BCAR1  4 0.556 3
 UniProt:Q68D51-2 DENND2C      0.556 3
 UniProt:A8MQ03 CRTP1      0.556 3
 UniProt:Q9UGK3 STAP2  2 0.556 3
 UniProt:Q96N16 JKIP1      0.556 3
 UniProt:Q14847-2 LASP1      0.556 3
 UniProt:Q6P1W5 CA094      0.556 3
 UniProt:Q8N9I9 DTX3      0.556 3
 UniProt:Q96Q35-2 FLACC1      0.556 3
 UniProt:Q9HD42 CHMP1A  1 0.556 3
 UniProt:Q9Y592-2 CEP83      0.556 3
 UniProt:O43281-2 EFS      0.556 5
 UniProt:O14512 SOCS7      0.556 3
 UniProt:Q9UKT9 IKZF3      0.556 5
 UniProt:Q8IYX8 CE57L      0.556 3
 UniProt:Q96GY0 ZC21A      0.556 3
 UniProt:Q9ULV8 CBLC      0.556 3
 UniProt:Q9C035-3 TRIM5      0.556 3
 UniProt:Q3SY00 T10IP      0.556 3
 UniProt:Q16630-2 CPSF6  1 0.556 3
 UniProt:Q8TD16-2 BICD2      0.556 3
 UniProt:Q15428 SF3A2  1 0.556 3
 UniProt:Q9GZT8 NIF3L      0.556 3
 UniProt:Q7Z4V0 ZN438      0.556 3
 UniProt:O95995 GAS8  1 0.556 3
 UniProt:O14508 SOCS2  1 0.556 3
 UniProt:Q9NRD5 PICK1  2 0.556 3
 UniProt:O60496 DOK2  1 0.556 3
 UniProt:P14136 GFAP  3 0.556 3
 UniProt:P46109 CRKL  2 0.556 3
 UniProt:P06239 LCK  4 0.527 3
 UniProt:P05120 SERPINB2  2 0.527 2
 UniProt:Q7Z3E2 CC186      0.527 2
 UniProt:Q13503 MED21  1 0.527 2
 UniProt:Q8NFB2 T185A      0.527 2
 UniProt:Q58FG1 HS904      0.527 2
 UniProt:Q58FG0 HS905      0.527 2
 UniProt:Q58FF6 H90B4      0.527 2
 UniProt:Q58FF7 H90B3      0.527 3
 UniProt:P09067 HXB5      0.527 2
 UniProt:Q9H204 MED28  1 0.524 2
 UniProt:P25445-1 FAS      0.499 2
 UniProt:Q14457 BECN1  4 0.488 2
 UniProt:Q08345-1 DDR1      0.462 7
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