Reactome | EEF1D [cytosol]

EEF1D [cytosol]

Stable Identifier

R-HSA-156914

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

EF-1-delta , Elongation factor 1-delta, eEF1B delta

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P29692 EEF1D

Gene Names

EEF1D, EF1D

Chain

initiator methionine:1, chain:2-281

Reference Genes

BioGPS Gene:1936 EEF1D

COSMIC (genes):EEF1D EEF1D

CTD Gene:1936 EEF1D

dbSNP Gene:1936 EEF1D

ENSEMBL:ENSG00000104529 EEF1D

ENSEMBL:ENSG00000273594 EEF1D

HGNC:3211 EEF1D

KEGG Gene (Homo sapiens):1936 EEF1D

Monarch:1936 EEF1D

NCBI Gene:1936 EEF1D

OMIM:130592 EEF1D

UCSC:P29692 EEF1D

Reference Transcript

Other Identifiers

0006900706

11730204_x_at

11741589_x_at

11754826_x_at

1936

203113_s_at

214394_x_at

3157597

3157598

3157599

3157600

3157603

3157605

3157606

3157613

3157614

3157616

3157617

3157619

3157623

3157624

3157627

3157635

3157636

3157637

3215040

3822577

3822579

3822580

3822582

3822584

41256_at

8153449

89262_at

A_23_P31833

A_23_P389708

GE60364

GO:0001650

GO:0003674

GO:0003677

GO:0003723

GO:0003746

GO:0005085

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005730

GO:0005737

GO:0005783

GO:0005829

GO:0005853

GO:0006412

GO:0006414

GO:0007165

GO:0008135

GO:0008150

GO:0009058

GO:0019899

GO:0032991

GO:0034641

GO:0043123

GO:0043226

GO:0045296

GO:0071479

Hs.223241.1.A1_3p_x_at

ILMN_1703635

ILMN_1782543

ILMN_2408039

Z21507_at

g4503478_3p_x_at

Participant Of

input

Formation of eEF1B complex

hasComponent

eEF1B complex [cytosol]

Inferred To

EFB1 [cytosol] (Saccharomyces cerevisiae)

tef5 [cytosol] (Schizosaccharomyces pombe)

EEF1D [cytosol] (Bos taurus)

EEF1D [cytosol] (Canis familiaris)

EEF1D [cytosol] (Gallus gallus)

EEF1D [cytosol] (Plasmodium falciparum)

EEF1D [cytosol] (Sus scrofa)

EEF1D [cytosol] (Xenopus tropicalis)

Eef1d [cytosol] (Mus musculus)

Eef1d [cytosol] (Rattus norvegicus)

Homologues of EEF1D [cytosol] (Plasmodium falciparum)

efa1B [cytosol] (Dictyostelium discoideum)

eEF1delta [cytosol] (Drosophila melanogaster)

eef1db [cytosol] (Danio rerio)

Cross References

RefSeq

XP_006716588.1, NP_001123527.1, XP_011515208.1, NP_001123528.1, NP_115754.3, NP_001304672.1, NP_001182132.1, NP_001317575.1, NP_001951.2, XP_006716586.1, NP_001276879.1, NP_001123529.1, XP_005250880.1, NP_001123525.2, XP_006716585.1, XP_016868659.1, XP_011515207.1, XP_006716587.1

Target Pathogen

5b354852be737e166372e862

OpenTargets

ENSG00000104529

HPA

ENSG00000104529-EEF1D

GeneCards

P29692

Ensembl

ENST00000632675, ENSP00000317399, ENST00000524624, ENST00000395119, ENSP00000431763, ENSP00000480505, ENST00000632587, ENSP00000410059, ENST00000620155, ENST00000615698, ENST00000614575, ENST00000528610, ENSP00000483527, ENSP00000435697, ENSP00000391944, ENST00000442189, ENST00000631698, ENSP00000388261, ENSP00000487680, ENST00000526838, ENSP00000478340, ENST00000632965, ENSP00000434872, ENSP00000477608, ENST00000419152, ENST00000619144, ENSP00000488672, ENST00000529272, ENST00000423316, ENST00000615067, ENSG00000273594, ENSP00000479653, ENSG00000104529, ENSP00000436507, ENSP00000488275, ENSP00000488026, ENST00000317198, ENSP00000378551

PRO

P29692

HMDB Protein

HMDBP08368

PDB

2MVN, 2MVM, 5JPO, 2N51

Interactors (14)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P26641 EEF1G	1	EEF1G [cytosol] (R-HSA-156925)	0.681	4
UniProt:Q96DN0 ERP27			0.666	4
UniProt:Q8IUQ4 SIAH1	1	SIAH1 [cytosol] (R-HSA-374563)	0.666	4
UniProt:P00441 SOD1	5	2xHC-SOD1 [mitochondrial intermembrane space] (R-HSA-3777108) SOD1 [extracellular region] (R-HSA-350705) SOD1 [mitochondrial intermembrane space] (R-HSA-3777082) SOD1 [cytosol] (R-HSA-350697) 2xHC-SOD1 [cytosol] (R-HSA-3299726)	0.564	3
UniProt:P13693 TCTP			0.556	3
UniProt:P26641-2 EEF1G			0.556	3
UniProt:P29692 EEF1D	1	EEF1D [cytosol] (R-HSA-156914)	0.553	2
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.527	3
UniProt:Q5T5U3 ARHGAP21	1	ARHGAP21 [cytosol] (R-HSA-8873918)	0.524	2
UniProt:O95352 ATG7	7	ATG7 [cytosol] (R-HSA-947867) ATG7 [secretory granule lumen] (R-HSA-6801316) CysO572-ATG7 [cytosol] (R-HSA-5683584) p-ATG7-BRAF fusion [cytosol] (R-HSA-6802517) ATG7-BRAF fusion [cytosol] (R-HSA-6802272) ATG7 [ficolin-1-rich granule lumen] (R-HSA-6801293) ATG7 [extracellular region] (R-HSA-6806451)	0.524	2
UniProt:Q08AD1 CAMP2			0.524	2
UniProt:Q67020 Q67020			0.508	2
UniProt:P61244 MAX	1	MAX [nucleoplasm] (R-HSA-3006627)	0.499	2
UniProt:P05412 JUN	4	p-S63,S73-JUN [nucleoplasm] (R-HSA-450237) JUN [nucleoplasm] (R-HSA-450250) JUN [cytosol] (R-HSA-168194) p-S63,S73-JUN [cytosol] (R-HSA-8868682)	0.462	4

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