Reactome | EEF1D [cytosol]

EEF1D [cytosol]

Stable Identifier

R-HSA-156914

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

EF-1-delta , Elongation factor 1-delta, eEF1B delta

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P29692 EEF1D

Gene Names

EEF1D, EF1D

Chain

initiator methionine:1, chain:2-281

Reference Genes

COSMIC (genes):EEF1D EEF1D

dbSNP Gene:1936 EEF1D

ENSEMBL:ENSG00000104529 EEF1D

Participates

as an input of

Formation of eEF1B complex (Homo sapiens)

as a component of

eEF1B complex [cytosol] (Homo sapiens)

Inferred To

EFB1 [cytosol] (Saccharomyces cerevisiae)

tef5 [cytosol] (Schizosaccharomyces pombe)

EEF1D [cytosol] (Bos taurus)

EEF1D [cytosol] (Canis familiaris)

EEF1D [cytosol] (Gallus gallus)

EEF1D [cytosol] (Plasmodium falciparum)

EEF1D [cytosol] (Sus scrofa)

Eef1d [cytosol] (Mus musculus)

Eef1d [cytosol] (Rattus norvegicus)

Homologues of EEF1D [cytosol] (Plasmodium falciparum)

efa1B [cytosol] (Dictyostelium discoideum)

eEF1delta [cytosol] (Drosophila melanogaster)

Interactors (19)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P26641 EEF1G	3	EEF1G(1-343)-p-6Y-ALK(1106-1620) fusion [cytosol] (R-HSA-9710850) EEF1G(1-343)-ALK(1106-1620) fusion [cytosol] (R-HSA-9710839) EEF1G [cytosol] (R-HSA-156925)	0.813	8
UniProt:Q96DN0 ERP27			0.743	5
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.742	6
UniProt:Q05639 EEF1A2	1	EEF1A2 [cytosol] (R-HSA-3907261)	0.669	6
UniProt:Q8IUQ4 SIAH1	1	SIAH1 [cytosol] (R-HSA-374563)	0.666	4
UniProt:P00441 SOD1	5	2xHC-SOD1 [cytosol] (R-HSA-3299726) SOD1 [cytosol] (R-HSA-350697) 2xHC-SOD1 [mitochondrial intermembrane space] (R-HSA-3777108) SOD1 [mitochondrial intermembrane space] (R-HSA-3777082) SOD1 [extracellular region] (R-HSA-350705)	0.564	3
UniProt:P13693 TCTP			0.556	3
UniProt:P26641-2 EEF1G			0.556	3
UniProt:P29692 EEF1D	1	EEF1D [cytosol] (R-HSA-156914)	0.553	2
UniProt:Q969K4 ABTB1			0.547	3
UniProt:P35453 HXD13			0.527	3
UniProt:P55197 AF10			0.527	2
UniProt:Q5T5U3 ARHGAP21	1	ARHGAP21 [cytosol] (R-HSA-8873918)	0.524	2
UniProt:O95352 ATG7	14	ATG7 [ficolin-1-rich granule lumen] (R-HSA-6801293) ATG7 [extracellular region] (R-HSA-6806451) ATG7 [secretory granule lumen] (R-HSA-6801316) ATG7(1-693)-BRAF(381-766) fusion [cytosol] (R-HSA-6802272) ATG7(1-693)-p-BRAF(381-766) fusion [cytosol] (R-HSA-6802517) CysO572-ATG7-MAP1LC3B [cytosol] (R-HSA-9820410) CysO572-ATG7-GARABAPL2 [cytosol] (R-HSA-9820413) CysO572-ATG7-GARABAP [cytosol] (R-HSA-9820417) CysO572-ATG7-GARABAPL1 [cytosol] (R-HSA-9820406) CysO572-ATG7-MAP1LC3C [cytosol] (R-HSA-9820407) CysO572-ATG7-MAP1LC3A [cytosol] (R-HSA-9820421) CysO572-ATG7-GARABAPL3 [cytosol] (R-HSA-9820420) CysO572-ATG7 [cytosol] (R-HSA-5683584) ATG7 [cytosol] (R-HSA-947867)	0.524	2
UniProt:Q08AD1 CAMP2			0.524	2
UniProt:Q67020 Q67020			0.508	2
UniProt:P61244 MAX	1	MAX [nucleoplasm] (R-HSA-3006627)	0.499	2
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.483	5
UniProt:P05412 JUN	4	JUN [nucleoplasm] (R-HSA-450250) p-S63,S73-JUN [nucleoplasm] (R-HSA-450237) JUN [cytosol] (R-HSA-168194) p-S63,S73-JUN [cytosol] (R-HSA-8868682)	0.462	4

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