RPA1 [nucleoplasm]

Stable Identifier
R-HSA-68461
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
DNA Replication factor A protein A1 (70kD), RPA70, Replication protein A 70 kDa DNA-binding subunit, RP-A, RF-A, Replication factor-A protein 1, Single-stranded DNA-binding protein
Icon
RPA1 [nucleoplasm] icon
RPA1 [nucleoplasm] icon
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:P27694 RPA1
Gene Names
RPA1, REPA1, RPA70
Chain
initiator methionine:1, chain:1-616, chain:2-616
Reference Genes
BioGPS Gene:6117 RPA1
COSMIC (genes):RPA1 RPA1
CTD Gene:6117 RPA1
dbSNP Gene:6117 RPA1
ENSEMBL:ENSG00000132383 RPA1
HGNC:10289 RPA1
KEGG Gene (Homo sapiens):6117 RPA1
Monarch:6117 RPA1
NCBI Gene:6117 RPA1
OMIM:179835 RPA1
UCSC:P27694 RPA1
Reference Transcript
Other Identifiers
11716571_at
11716572_s_at
1382_at
16829580
201528_at
201529_s_at
236675_at
3706001
3706002
3706003
3706006
3706007
3706008
3706010
3706017
3706018
3706019
3706020
3706021
3706022
3706023
3706024
3706026
3706028
3706029
3706032
3706033
3706034
3706035
38481_at
59166_at
6117
8003679
A_14_P107237
A_33_P3218951
GE58026
GO:0000003
GO:0000228
GO:0000723
GO:0000724
GO:0000781
GO:0003674
GO:0003676
GO:0003677
GO:0003684
GO:0003697
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005662
GO:0005694
GO:0006259
GO:0006260
GO:0006261
GO:0006268
GO:0006270
GO:0006281
GO:0006283
GO:0006284
GO:0006287
GO:0006289
GO:0006293
GO:0006294
GO:0006295
GO:0006296
GO:0006297
GO:0006298
GO:0006310
GO:0006950
GO:0006974
GO:0007004
GO:0007049
GO:0007165
GO:0008150
GO:0009058
GO:0016605
GO:0019985
GO:0022607
GO:0032201
GO:0032991
GO:0033683
GO:0034502
GO:0034641
GO:0036297
GO:0042276
GO:0042592
GO:0042769
GO:0043047
GO:0043167
GO:0043226
GO:0046872
GO:0051276
GO:0051321
GO:0065003
GO:0070987
GO:0090734
GO:0098505
GO:1900034
GO:1901796
HMNXSV003007431
Hs.135292.0.A1_3p_at
Hs.84318.0.S2_3p_at
ILMN_1795719
ILMN_3249261
M63488_at
PH_hs_0004794
TC17000016.hg
TC17002004.hg
g4506582_3p_a_at
Participates
as an input of
as a component of
Other forms of this molecule
SUMO2,3-K449,K577-RPA1 [nucleoplasm]
Inferred To
rpa1 [nucleoplasm] (Danio rerio)
rpa1 [nucleoplasm] (Xenopus tropicalis)
ssb1 [nucleoplasm] (Schizosaccharomyces pombe)
Rpa1 [nucleoplasm] (Mus musculus)
Rpa1 [nucleoplasm] (Rattus norvegicus)
Ghost homologue of RPA1 [nucleoplasm] (Bos taurus)
Ghost homologue of RPA1 [nucleoplasm] (Caenorhabditis elegans)
Ghost homologue of RPA1 [nucleoplasm] (Dictyostelium discoideum)
RFA1 [nucleoplasm] (Saccharomyces cerevisiae)
RpA-70 [nucleoplasm] (Drosophila melanogaster)
RPA1 [nucleoplasm] (Canis familiaris)
RPA1 [nucleoplasm] (Gallus gallus)
RPA1 [nucleoplasm] (Sus scrofa)
Cross References
RefSeq
OpenTargets
HPA
GeneCards
ZINC - Substances
Ensembl
ZINC target
PRO
Pharos - Targets
ZINC - Predictions - Purchasable
GlyGen
PDB
Interactors (17)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P15927 RPA2  2 0.953 15
 UniProt:P35244 RPA3  1 0.924 11
 UniProt:Q14191 WRN  2 0.818 9
 UniProt:P03070 LT      0.672 4
 UniProt:Q13156 RPA4  1 0.67 6
 UniProt:P54132 BLM  2 0.669 4
 UniProt:P38398 BRCA1  27 0.65 3
 UniProt:Q96LW4 PRIPO      0.623 7
 UniProt:P03116 VE1      0.558 2
 UniProt:Q5JR59-3 MTUS2      0.556 3
 UniProt:Q5JR59 MTUS2      0.556 3
 UniProt:P17066 HSPA6  5 0.556 3
 UniProt:Q9H9A7 RMI1  1 0.527 2
 UniProt:Q9NZC9 SMAL1      0.527 2
 UniProt:P23025 XPA  1 0.527 2
 UniProt:Q9UGP5 POLL  1 0.508 2
 UniProt:P51587 BRCA2  2 0.462 3
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