Reactome | WAPAL [chromosome]

WAPAL [chromosome]

Stable Identifier

R-HSA-2577090

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

chromosome

Synonyms

Wings apart-like protein homolog, FOE, WAPL

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q7Z5K2 WAPL

Gene Names

WAPL, FOE, KIAA0261, WAPAL

Chain

chain:1-1190

Reference Genes

BioGPS Gene:23063 WAPL

COSMIC (genes):WAPL WAPL

CTD Gene:23063 WAPL

dbSNP Gene:23063 WAPL

ENSEMBL:ENSG00000062650 WAPL

ENSEMBL_homo_sapiens_GENE:ENSG00000062650.20 WAPL

HGNC:23293 WAPL

KEGG Gene (Homo sapiens):23063 WAPL

Monarch:23063 WAPL

NCBI Gene:23063 WAPL

OMIM:610754 WAPL

UCSC:Q7Z5K2 WAPL

Reference Transcript

Other Identifiers

11730897_a_at

11730898_a_at

11730899_s_at

11750328_s_at

11750329_x_at

1554441_PM_a_at

1554441_a_at

16716185

212264_PM_s_at

212264_s_at

212267_PM_at

212267_at

23063

3298739

3298740

3298741

3298742

3298743

3298744

3298746

3298747

3298751

3298752

3298754

3298755

3298756

3298757

3298758

3298759

3298761

3298762

3298763

3298764

3298765

3298766

3298767

3298768

3298769

3298770

3298771

3298773

3298774

3298775

3298776

3298777

3298778

40086_at

7934812

A_23_P342185

A_32_P174908

D87450_at

GE57404

GO:0000070

GO:0000278

GO:0000775

GO:0000785

GO:0003824

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0005737

GO:0005829

GO:0005856

GO:0006260

GO:0007049

GO:0007059

GO:0008156

GO:0035562

GO:0043226

GO:0043231

GO:0045171

GO:0045875

GO:0051301

GO:0071168

GO:0071922

GO:0072686

GO:0140014

GO:0140083

GO:0140097

GO:0140657

HMNXSV003051682

Hs.154978.0.S1_3p_a_at

Hs.154978.0.S2_3p_at

Hs2.154978.2.A1_3p_s_at

ILMN_1693668

PH_hs_0025733

TC10001480.hg

TC10002752.hg

Participates

as a component of

Other forms of this molecule

WAPAL [cytosol]

WAPAL [chromosome, centromeric region]

WAPAL [nucleoplasm]

Inferred To

Ghost homologue of WAPAL [chromosome] (Danio rerio)

Ghost homologue of WAPAL [chromosome] (Dictyostelium discoideum)

Ghost homologue of WAPAL [chromosome] (Saccharomyces cerevisiae)

Ghost homologue of WAPAL [chromosome] (Xenopus tropicalis)

WAPAL [chromosome] (Gallus gallus)

wpl1 [chromosome] (Schizosaccharomyces pombe)

WAPL [chromosome] (Bos taurus)

WAPL [chromosome] (Canis familiaris)

WAPL [chromosome] (Sus scrofa)

Wapl [chromosome] (Mus musculus)

Wapl [chromosome] (Rattus norvegicus)

wapl [chromosome] (Drosophila melanogaster)

wapl-1 [chromosome] (Caenorhabditis elegans)

Cross References

RefSeq

NP_001305257.1, NP_055860.1

OpenTargets

ENSG00000062650

GeneCards

Q7Z5K2

HPA

ENSG00000062650-WAPL

Ensembl

ENSP00000298767, ENST00000298767, ENSG00000062650

PRO

Q7Z5K2

Pharos - Targets

Q7Z5K2

PDB

4K6J, 5HDT

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8N3U4 STAG2	8	monoSUMO1-K-STAG2 [nucleoplasm] (R-HSA-3108187) p-STAG2 [chromosome, centromeric region] (R-HSA-2466013) p-STAG2 [cytosol] (R-HSA-2484806) p-STAG2 [chromosome] (R-HSA-1638793) STAG2 [cytosol] (R-HSA-2484897) STAG2 [chromosome] (R-HSA-1638777) STAG2 [chromosome, centromeric region] (R-HSA-2466018) STAG2 [nucleoplasm] (R-HSA-163046)	0.922	14
UniProt:O60216 RAD21	14	monoSUMO1-K-RAD21 [nucleoplasm] (R-HSA-3108183) p-S454-RAD21 [cytosol] (R-HSA-2500310) p-S454-RAD21 [chromosome] (R-HSA-2485164) RAD21 [cytosol] (R-HSA-2484795) p-S454-RAD21(451-631) [cytosol] (R-HSA-2500309) RAD21(173-450) [cytosol] (R-HSA-2500308) RAD21(1-172) [cytosol] (R-HSA-2484901) RAD21(173-450) [chromosome, centromeric region] (R-HSA-2500296) p-S454-RAD21(451-631) [chromosome, centromeric region] (R-HSA-2467790) RAD21(1-172) [chromosome, centromeric region] (R-HSA-2467793) p-S454-RAD21 [chromosome, centromeric region] (R-HSA-2485163) RAD21 [chromosome] (R-HSA-1638775) RAD21 [nucleoplasm] (R-HSA-163042) RAD21 [chromosome, centromeric region] (R-HSA-2466012)	0.905	18
UniProt:Q14683 SMC1A	4	SMC1A [cytosol] (R-HSA-2484798) SMC1A [chromosome] (R-HSA-1638774) SMC1A [chromosome, centromeric region] (R-HSA-2466015) SMC1A [nucleoplasm] (R-HSA-64561)	0.857	15
UniProt:Q9UQE7 SMC3	6	SMC3 [cytosol] (R-HSA-2545223) 2xAcK-SMC3 [cytosol] (R-HSA-2484792) 2xAcK-SMC3 [chromosome] (R-HSA-2468146) 2xAcK-SMC3 [chromosome, centromeric region] (R-HSA-2468148) 2xAcK-SMC3 [nucleoplasm] (R-HSA-2468050) SMC3 [nucleoplasm] (R-HSA-163009)	0.822	13
UniProt:Q29RF7 PDS5A	4	PDS5A [cytosol] (R-HSA-2484799) PDS5A [chromosome] (R-HSA-2466360) PDS5A [chromosome, centromeric region] (R-HSA-2468259) PDS5A [nucleoplasm] (R-HSA-2468043)	0.813	9
UniProt:Q8WVM7 STAG1	4	STAG1 [cytosol] (R-HSA-2484793) STAG1 [chromosome] (R-HSA-1638773) STAG1 [nucleoplasm] (R-HSA-163016) STAG1 [chromosome, centromeric region] (R-HSA-2466017)	0.813	10
UniProt:Q9NTI5 PDS5B	4	PDS5B [cytosol] (R-HSA-2484800) PDS5B [chromosome] (R-HSA-2466361) PDS5B [chromosome, centromeric region] (R-HSA-2468263) PDS5B [nucleoplasm] (R-HSA-2468051)	0.734	9
UniProt:Q9CW03 Smc3	6	SMC3 [cytosol] (R-MMU-2545223) 2xAcK-SMC3 [cytosol] (R-MMU-2484792) 2xAcK-SMC3 [chromosome] (R-MMU-2468146) 2xAcK-SMC3 [chromosome, centromeric region] (R-MMU-2468148) 2xAcK-SMC3 [nucleoplasm] (R-MMU-2468050) Structural maintenance of chromosomes protein 3 [nucleoplasm] (R-MMU-912387)	0.597	4
UniProt:Q7Z5K2 WAPL	4	WAPAL [cytosol] (R-HSA-2484802) WAPAL [chromosome] (R-HSA-2577090) WAPAL [chromosome, centromeric region] (R-HSA-2577088) WAPAL [nucleoplasm] (R-HSA-2466355)	0.564	2

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