Reactome | MCRS1 [nucleoplasm]

MCRS1 [nucleoplasm]

Stable Identifier

R-HSA-3321849

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Microspherule protein 1, MCRS1_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q96EZ8 MCRS1

Gene Names

MCRS1, INO80Q, MSP58

Chain

chain:1-462

Reference Genes

BioGPS Gene:10445 MCRS1

COSMIC (genes):MCRS1 MCRS1

CTD Gene:10445 MCRS1

dbSNP Gene:10445 MCRS1

ENSEMBL:ENSG00000187778.14 MCRS1

HGNC:6960 MCRS1

KEGG Gene (Homo sapiens):10445 MCRS1

Monarch:10445 MCRS1

NCBI Gene:10445 MCRS1

OMIM:609504 MCRS1

UCSC:Q96EZ8 MCRS1

Reference Transcript

Other Identifiers

0003390092

10445

11718162_a_at

16764348

202556_PM_s_at

202556_s_at

33898_at

3453905

3453906

3453908

3453910

3453912

3453914

3453916

3453917

3453920

3453921

3453922

3453923

3453925

3453926

3453928

3453929

3453930

3453933

3453934

3453937

7963064

A_23_P48237

GE81623

GO:0000123

GO:0000228

GO:0000723

GO:0002151

GO:0003723

GO:0005515

GO:0005622

GO:0005634

GO:0005654

GO:0005694

GO:0005730

GO:0005737

GO:0005783

GO:0005844

GO:0006260

GO:0006275

GO:0006281

GO:0006282

GO:0006310

GO:0006325

GO:0006338

GO:0006351

GO:0006355

GO:0006974

GO:0008266

GO:0010521

GO:0030425

GO:0031011

GO:0032200

GO:0032991

GO:0033044

GO:0034046

GO:0036211

GO:0043204

GO:0043226

GO:0043981

GO:0043982

GO:0043984

GO:0044545

GO:0045739

GO:0045893

GO:0045944

GO:0045995

GO:0048856

GO:0051571

GO:0051726

GO:0051974

GO:0060382

GO:0071339

GO:0098772

GO:1900095

GO:1904357

GO:1904507

GO:1904751

HMNXSV003025875

ILMN_1713147

ILMN_1773419

ILMN_1784227

PH_hs_0002226

TC12001478.hg

TC12002870.hg

g5453693_3p_a_at

Participates

as a component of

Inferred To

znf519 [nucleoplasm] (Xenopus tropicalis)

Mcrs1 [nucleoplasm] (Mus musculus)

Mcrs1 [nucleoplasm] (Rattus norvegicus)

MCRS1 [nucleoplasm] (Bos taurus)

MCRS1 [nucleoplasm] (Canis familiaris)

MCRS1 [nucleoplasm] (Danio rerio)

MCRS1 [nucleoplasm] (Gallus gallus)

MCRS1 [nucleoplasm] (Sus scrofa)

Rcd5 [nucleoplasm] (Drosophila melanogaster)

Cross References

RefSeq

NP_006328.2, XP_016874178.1, XP_005268629.1, XP_016874179.1, NP_001012300.1, NP_001265270.1

OpenTargets

ENSG00000187778

GeneCards

Q96EZ8

HPA

ENSG00000187778-MCRS1

Ensembl

ENST00000546244, ENSP00000345358, ENST00000357123, ENSP00000349640, ENSP00000448056, ENSP00000444982, ENST00000343810, ENST00000550165, ENSG00000187778

PRO

Q96EZ8

Pharos - Targets

Q96EZ8

Interactors (22)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9UER7 DAXX	13	monoSUMO1-K630,K631-DAXX [nucleoplasm] (R-HSA-4086086) DAXX L98Vfs13 [nucleoplasm] (R-HSA-9673102) DAXX R48Vfs93 [nucleoplasm] (R-HSA-9673103) DAXX C74* [nucleoplasm] (R-HSA-9673096) DAXX S138* [nucleoplasm] (R-HSA-9673081) DAXX H26Tfs118 [nucleoplasm] (R-HSA-9673114) DAXX E104 [nucleoplasm] (R-HSA-9673078) DAXX E72Nfs72 [nucleoplasm] (R-HSA-9673110) DAXX C106 [nucleoplasm] (R-HSA-9673079) DAXX A103Sfs40 [nucleoplasm] (R-HSA-9673121) DAXX K56 [nucleoplasm] (R-HSA-9673089) DAXX A36Qfs*108 [nucleoplasm] (R-HSA-9673105) DAXX [nucleoplasm] (R-HSA-3222068)	0.793	11
UniProt:Q9Y2W2 WBP11	1	WBP11 [nucleoplasm] (R-HSA-8867887)	0.696	5
UniProt:P25490 YY1	1	YY1 [nucleoplasm] (R-HSA-4086091)	0.671	4
UniProt:Q9NPJ6 MED4	1	MED4 [nucleoplasm] (R-HSA-350263)	0.666	4
UniProt:P61964 WDR5	1	WDR5 [nucleoplasm] (R-HSA-1629838)	0.643	3
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	3
UniProt:Q08379 GOLGA2	3	p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.556	3
UniProt:O14503 BHLHE40	1	BHLHE40 [nucleoplasm] (R-HSA-879741)	0.556	3
UniProt:Q99683 MAP3K5	1	MAP3K5 [cytosol] (R-HSA-167709)	0.556	3
UniProt:P55040 GEM	1	GEM [plasma membrane] (R-HSA-9769962)	0.556	3
UniProt:Q68CJ9 CREB3L3	10	CREB3L3(1-?) [nucleoplasm] (R-HSA-6784629) CREB3L3(1-?) [cytosol] (R-HSA-6784654) CREB3L3 [endoplasmic reticulum membrane] (R-HSA-6784669) CREB3L3(?-461) [endoplasmic reticulum membrane] (R-HSA-6784710) CREB3L3 [Golgi membrane] (R-HSA-8874144) CREB3L3(365-461) [Golgi membrane] (R-HSA-8874130) CREB3L3(1-364) [Golgi membrane] (R-HSA-8874158) CREB3L3(1-323) [cytosol] (R-HSA-8874214) CREB3L3(1-323) [nucleoplasm] (R-HSA-8874217) CREB3L3(324-364) [Golgi membrane] (R-HSA-8874183)	0.556	3
UniProt:P06396 GSN	7	GSN(200-270) [extracellular region] (R-HSA-976940) GSN [secretory granule lumen] (R-HSA-6801486) GSN [extracellular region] (R-HSA-6806510) GSN [ficolin-1-rich granule lumen] (R-HSA-6801465) GSN(404-782) [cytosol] (R-HSA-350272) GSN(28-403) [cytosol] (R-HSA-201618) GSN [cytosol] (R-HSA-350275)	0.556	3
UniProt:Q9UGI0 ZRANB1	1	ZRANB1 [cytosol] (R-HSA-6781939)	0.556	3
UniProt:Q15742 NAB2	1	NAB2 [nucleoplasm] (R-HSA-9612177)	0.556	3
UniProt:Q9H2G4 TSPYL2	1	TSPYL2 [nucleoplasm] (R-HSA-535540)	0.556	5
UniProt:P14136 GFAP	3	p-GFAP [lysosomal membrane] (R-HSA-9626054) GFAP [lysosomal membrane] (R-HSA-9625195) GFAP [cytosol] (R-HSA-1253311)	0.556	3
UniProt:Q86TI0 TBC1D1	2	TBC1D1 [cytoplasmic vesicle membrane] (R-HSA-1454718) p-S237-TBC1D1 [cytosol] (R-HSA-1454673)	0.556	3
UniProt:P50548 ERF	3	ERF [nucleoplasm] (R-HSA-2534321) p-T526-ERF [cytosol] (R-HSA-3209167) p-T526-ERF [nucleoplasm] (R-HSA-3209166)	0.556	3
UniProt:P55081 MFAP1	1	MFAP1 [nucleoplasm] (R-HSA-2396419)	0.556	3
UniProt:P98170 XIAP	3	XIAP [nucleoplasm] (R-HSA-3322366) K48pUb-XIAP [cytosol] (R-HSA-5675477) XIAP [cytosol] (R-HSA-50849)	0.556	3
UniProt:P10276 RARA	3	SUMO2-K166,177,399-p-S219,269-RARA [nucleoplasm] (R-HSA-5334830) polySUMO2-K166,K171,K399-RARA [nucleoplasm] (R-HSA-4341042) RARA [nucleoplasm] (R-HSA-446164)	0.556	3
UniProt:Q9Y2T1 AXIN2	4	AXIN2 [cytosol] (R-HSA-3640821) RibC-AXIN2 [cytosol] (R-HSA-3640842) Ub-RibC-AXIN2 [cytosol] (R-HSA-3640859) ub-AXIN2 [cytosol] (R-HSA-4641131)	0.556	3

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