Reactome | RBM39 [nucleoplasm]

RBM39 [nucleoplasm]

Stable Identifier

R-HSA-9770254

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

fullName evidence="18"RNA-binding protein 39, RBM39_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q14498 RBM39

Gene Names

RBM39, HCC1, RNPC2

Chain

initiator methionine:1, chain:2-530

Reference Genes

BioGPS Gene:9584 RBM39

COSMIC (genes):RBM39 RBM39

CTD Gene:9584 RBM39

dbSNP Gene:9584 RBM39

ENSEMBL:ENSG00000131051 RBM39

ENSEMBL:ENSG00000131051.24 RBM39

HGNC:15923 RBM39

KEGG Gene (Homo sapiens):9584 RBM39

Monarch:9584 RBM39

NCBI Gene:9584 RBM39

OMIM:604739 RBM39

UCSC:Q14498 RBM39

Reference Transcript

Other Identifiers

11717086_x_at

11717087_s_at

11717088_s_at

11717089_x_at

11746566_x_at

11752629_s_at

11752630_x_at

207941_PM_s_at

207941_s_at

208720_PM_s_at

208720_s_at

3904117

3904212

3904213

3904214

3904215

3904216

3904217

3904218

3904219

3904227

3904228

3904229

3904230

3904231

3904232

3904234

3904236

3904240

3904241

3904245

3904246

3904248

3904249

3904250

3904251

3904255

3904257

3904260

3904274

3904282

3904285

3904286

39725_at

3975316

8066009

9584

A_23_P109254

A_33_P3324651

GE57604

GO:0003676

GO:0003723

GO:0005515

GO:0005634

GO:0005654

GO:0005815

GO:0005856

GO:0006396

GO:0006397

GO:0008380

GO:0015630

GO:0016071

GO:0016607

GO:0032991

GO:0034451

GO:0043226

GO:0048024

GO:0050733

GO:1990446

HMNXSV003014372

Hs.145696.1.A1_3p_a_at

ILMN_1696935

L10910_at

PH_hs_0029608

TC20001560.hg

g4757925_3p_a_at

Participates

as an output of

Formation of the Spliceosomal B complex (Homo sapiens)

as an input of

Formation of the Spliceosomal E complex (Homo sapiens)

as a component of

Inferred To

RBM23 [nucleoplasm] (Gallus gallus)

RBM39 [nucleoplasm] (Bos taurus)

RBM39 [nucleoplasm] (Canis familiaris)

RBM39 [nucleoplasm] (Plasmodium falciparum)

RBM39 [nucleoplasm] (Sus scrofa)

rsd1 [nucleoplasm] (Schizosaccharomyces pombe)

Caper [nucleoplasm] (Drosophila melanogaster)

Ghost homologue of RBM39 [nucleoplasm] (Caenorhabditis elegans)

Ghost homologue of RBM39 [nucleoplasm] (Dictyostelium discoideum)

Rbm39 [nucleoplasm] (Mus musculus)

Rbm39 [nucleoplasm] (Rattus norvegicus)

rbm39 [nucleoplasm] (Xenopus tropicalis)

rnpc2 [nucleoplasm] (Danio rerio)

Cross References

RefSeq

NP_909122.1, NP_001229528.1, NP_001229529.1, NP_004893.1

OpenTargets

ENSG00000131051

GeneCards

Q14498

HPA

ENSG00000131051-RBM39

Ensembl

ENSP00000436747, ENSP00000253363, ENSP00000354437, ENSG00000131051, ENST00000253363, ENST00000361162, ENST00000528062

PRO

Q14498

Pharos - Targets

Q14498

PDB

6Q0V, 4OO6, 7Q33, 4YUD, 2JRS, 6Q0W, 6UD7, 4OZ0, 2MHN, 6UE5, 6SJ7, 4OZ1, 6PAI, 6Q0R

Interactors (33)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P78362 SRPK2	1	SRPK2 [cytosol] (R-HSA-9729332)	0.837	10
UniProt:P49760 CLK2			0.782	9
UniProt:O00422 SAP18	1	SAP18 [nucleoplasm] (R-HSA-351694)	0.781	9
UniProt:O75400-2 PRPF40A			0.718	6
UniProt:Q6ZUT1 NKAP1			0.718	6
UniProt:Q9NVV9 THAP1			0.718	6
UniProt:Q8TBK6 ZCH10			0.666	4
UniProt:Q96SB4 SRPK1	2	SRPK1 [nucleoplasm] (R-HSA-9821984) SRPK1 [cytosol] (R-HSA-9729349)	0.642	3
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.615	14
UniProt:P59991 KRTAP12-2	1	KRTAP12-2 [cytosol] (R-HSA-6810271)	0.556	3
UniProt:Q9C086 INO80B	1	INO80B [nucleoplasm] (R-HSA-5689599)	0.556	3
UniProt:P68400 CSNK2A1	2	CSNK2A1 [nucleoplasm] (R-HSA-6805057) CSNK2A1 [cytosol] (R-HSA-201713)	0.556	3
UniProt:Q8WXA9 SREK1			0.556	3
UniProt:P67870 CSNK2B	5	CSNK2B [secretory granule lumen] (R-HSA-6801319) CSNK2B [extracellular region] (R-HSA-6806508) CSNK2B [ficolin-1-rich granule lumen] (R-HSA-6801290) CSNK2B [nucleoplasm] (R-HSA-6805067) CSNK2B [cytosol] (R-HSA-201693)	0.556	3
UniProt:Q7Z7F0 KHDC4			0.556	3
UniProt:P78424 PO6F2			0.556	3
UniProt:A7MD48 SRRM4			0.556	3
UniProt:P13473-2 P134732			0.556	3
UniProt:Q66PJ3-3 ARL6IP4			0.556	3
UniProt:Q6ZUT1-2 NKAPD1			0.556	3
UniProt:Q05519-2 SRSF11			0.556	5
UniProt:A0A024RA76 A0A024RA76			0.556	3
UniProt:Q8IXK0 PHC2	1	PHC2 [nucleoplasm] (R-HSA-389112)	0.556	3
UniProt:Q96MA6 AK8	1	AK8 [cytosol] (R-HSA-6788788)	0.556	3
UniProt:Q92997 DVL3	4	pp-DVL3 [cytosol] (R-HSA-3772400) p-DVL3 [cytosol] (R-HSA-201680) DVL3 [cytosol] (R-HSA-201678) ub-DVL3 [cytosol] (R-HSA-4652688)	0.556	3
UniProt:Q15427 SF3B4	1	SF3B4 [nucleoplasm] (R-HSA-71975)	0.556	3
UniProt:Q8N9Q2 SR1IP			0.556	3
UniProt:Q13427 PPIG	2	PPIG [cytosol] (R-HSA-9728768) PPIG [nucleoplasm] (R-HSA-9769592)	0.556	3
UniProt:O00560 SDCBP	3	SDCBP [extracellular region] (R-HSA-6806206) SDCBP [azurophil granule lumen] (R-HSA-6799372) SDCBP [cytosol] (R-HSA-373639)	0.556	3
UniProt:Q05519 SRSF11	1	SRSF11 [nucleoplasm] (R-HSA-72058)	0.556	3
UniProt:Q9UPE1 SRPK3			0.527	2
UniProt:Q5S007 LRRK2	1	LRRK2 [cytosol] (R-HSA-5661173)	0.527	3
UniProt:P03372 ESR1	8	p-S118-ESR1 [nucleoplasm] (R-HSA-9024210) monoSUMO1-5K-ESR1 [nucleoplasm] (R-HSA-4090302) PalmS-ESR1 [cytosol] (R-HSA-9020974) PalmS-ESR1 [plasma membrane] (R-HSA-9021057) Me260-PalmS-ESR1 [plasma membrane] (R-HSA-9637788) Me260-ESR1 [cytosol] (R-HSA-9632177) ESR1 [nucleoplasm] (R-HSA-446168) ESR1 [cytosol] (R-HSA-9020968)	0.462	2

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