p-S303,307-HSF1 [cytosol]

Stable Identifier
R-HSA-4793922
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
p-S303,307-Heat shock transcription factor 1, HSTF 1, Heat shock factor protein 1
Icon
p-S303,307-HSF1 [cytosol] icon
p-S303,307-HSF1 [cytosol] icon
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:Q00613 HSF1
Gene Names
HSF1, HSTF1
Chain
chain:1-529
Reference Genes
BioGPS Gene:3297 HSF1
COSMIC (genes):HSF1 HSF1
CTD Gene:3297 HSF1
dbSNP Gene:3297 HSF1
ENSEMBL:ENSG00000185122 HSF1
ENSEMBL:ENSG00000284774 HSF1
HGNC:5224 HSF1
KEGG Gene (Homo sapiens):3297 HSF1
Monarch:3297 HSF1
NCBI Gene:3297 HSF1
OMIM:140580 HSF1
UCSC:Q00613 HSF1
Reference Transcript
Other Identifiers
0005220722
11723695_s_at
17073759
202344_at
213756_s_at
244_at
2LDU
3120359
3120360
3120361
3120362
3120384
3120386
3120387
3120388
3120392
3120393
3120394
3120395
3120396
3120397
3120398
3120405
3120407
3120408
3120410
3120411
3120412
3120413
3297
40200_at
4049903
4049904
4049905
4049907
4049908
4049909
4049910
4049918
4049920
4049921
4049922
4049923
4049924
4049927
4049928
4049929
4239
5D5U
5D5V
5HDG
5HDN
8148824
8888
A0A087WWQ3
A0A087WXG6
A_23_P253841
A_33_P3347932
A_33_P3347937
AAA52695
AAH14638
AAP36015
AC110280
AF205589
AK290975
BAF83664
BC014638
BT007351
CAB004239
CCDS6419
E9PI02
E9PMQ6
ENSG00000185122
ENSG00000284774
ENSP00000431512
ENSP00000493830
ENST00000528838
ENST00000528838.5
ENST00000646252
EntrezGene:3297
EntrezGene:HSF1
g5031766_3p_at
g5031766_3p_x_at
GO:0000003
GO:0000122
GO:0000165
GO:0000228
GO:0000278
GO:0000775
GO:0000776
GO:0000777
GO:0000790
GO:0000791
GO:0000792
GO:0000922
GO:0000978
GO:0000981
GO:0001162
GO:0001227
GO:0001701
GO:0001892
GO:0003674
GO:0003677
GO:0003682
GO:0003700
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005654
GO:0005694
GO:0005737
GO:0005813
GO:0005815
GO:0005829
GO:0005856
GO:0006259
GO:0006281
GO:0006355
GO:0006397
GO:0006464
GO:0006468
GO:0006810
GO:0006950
GO:0006952
GO:0006974
GO:0007049
GO:0007143
GO:0007165
GO:0007283
GO:0007584
GO:0008150
GO:0008219
GO:0008283
GO:0008284
GO:0008285
GO:0009056
GO:0009058
GO:0009299
GO:0009408
GO:0009790
GO:0010243
GO:0010628
GO:0010629
GO:0010667
GO:0014070
GO:0014823
GO:0016605
GO:0019899
GO:0019901
GO:0022607
GO:0031072
GO:0031490
GO:0032355
GO:0032496
GO:0032720
GO:0032991
GO:0033574
GO:0034605
GO:0034620
GO:0034622
GO:0034641
GO:0034655
GO:0035690
GO:0035865
GO:0040007
GO:0040018
GO:0042531
GO:0042592
GO:0042802
GO:0043200
GO:0043226
GO:0043280
GO:0043497
GO:0043565
GO:0043621
GO:0045120
GO:0045931
GO:0045944
GO:0046982
GO:0048471
GO:0048856
GO:0051028
GO:0051260
GO:0051879
GO:0060136
GO:0061408
GO:0061770
GO:0065003
GO:0070207
GO:0070301
GO:0071222
GO:0071230
GO:0071276
GO:0071280
GO:0071392
GO:0071407
GO:0071478
GO:0071480
GO:0072738
GO:0090084
GO:0090261
GO:0097165
GO:0097431
GO:0097677
GO:0098847
GO:0120162
GO:1900034
GO:1900365
GO:1901215
GO:1901652
GO:1902512
GO:1903936
GO:1904385
GO:1904528
GO:1904843
GO:1904845
GO:1990841
GO:1990904
GO:1990910
GO:1990911
GO:2001033
HGNC:5224
HPA008888
Hs.1499.1.S1_3p_a_at
HSF1
HSF1-204
HSF1-226
ILMN_1665621
ILMN_1667060
ILMN_1679371
ILMN_1679867
IPR000232
IPR010542
IPR027725
IPR036388
IPR036390
M64673
M64673_at
MIM:140580
NM_005526
NP_005517
PF00447
PF06546
PH_hs_0031748
PR00056
SM00415
TC08000849.hg
TC08002160.hg
UPI0000000DE5
XM_005272315
XM_011517004
XM_017013377
XM_024447144
XP_005272372
XP_011515306
XP_016868866
XP_024302912
XR_001745526
XR_001745527
XR_246618
Participant Of
hasComponent
input
Other forms of this molecule
p-S121-HSF1 [cytosol]
p-S303-HSF1 [cytosol]
p-S307-HSF1 [cytosol]
HSF1 [nucleoplasm]
hC36,103-HSF1 [cytosol]
p-S230-hC36,103-HSF1 [nucleoplasm]
p-S326-hC36,103-HSF1 [nucleoplasm]
Ac-K80-hC36,103-HSF1 [nucleoplasm]
HSF1 [cytosol]
hC36,103-HSF1 [nucleoplasm]
Inferred To
Homologues of p-S303,307-HSF1 [cytosol] (Saccharomyces cerevisiae)
phospho-p-S303,307-HSF1 [cytosol] (Bos taurus)
phospho-p-S303,307-HSF1 [cytosol] (Canis familiaris)
phospho-p-S303,307-HSF1 [cytosol] (Danio rerio)
phospho-p-S303,307-HSF1 [cytosol] (Dictyostelium discoideum)
phospho-p-S303,307-HSF1 [cytosol] (Drosophila melanogaster)
phospho-p-S303,307-HSF1 [cytosol] (Mus musculus)
phospho-p-S303,307-HSF1 [cytosol] (Rattus norvegicus)
phospho-p-S303,307-HSF1 [cytosol] (Saccharomyces cerevisiae)
phospho-p-S303,307-HSF1 [cytosol] (Schizosaccharomyces pombe)
phospho-p-S303,307-HSF1 [cytosol] (Sus scrofa)
phospho-p-S303,307-HSF1 [cytosol] (Xenopus tropicalis)
Modified Residues
Name
O-phospho-L-serine at 307
Coordinate
307
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 303
Coordinate
303
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
ZINC - Metabolites
OpenTargets
ZINC - Substances
GeneCards
ZINC - Biogenic
ZINC target
PRO
Orphanet
ZINC - Predictions - Purchasable
PDB
Interactors (19)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q03933 HSF2      0.729 8
 UniProt:Q9NZL4 HPBP1      0.638 3
 UniProt:O00505 KPNA3  2 0.638 3
 UniProt:O00629 KPNA4  2 0.638 3
 UniProt:O95817 BAG3  1 0.638 3
 UniProt:Q00613 HSF1  11 0.609 2
 UniProt:P49137 MAPKAPK2  5 0.602 5
 UniProt:Q5VY09 IER5      0.589 3
 UniProt:Q8N4C8 MINK1  1 0.544 2
 UniProt:Q04759 PRKCQ  9 0.544 2
 UniProt:P62258 YWHAE  1 0.527 2
 UniProt:Q8NEH6 MNS1      0.508 2
 UniProt:Q8NET4 RTL9      0.508 2
 UniProt:P34931 HSPA1L  2 0.508 2
 UniProt:Q96SB8 SMC6  1 0.508 2
 UniProt:O43683 BUB1  1 0.508 2
 UniProt:Q15029 EFTUD2  1 0.508 2
 UniProt:Q5VZK9 CARMIL1  1 0.508 2
 UniProt:P53350 PLK1  4 0.508 2