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SKP2 [nucleoplasm]
Stable Identifier
R-HSA-975554
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
S-phase kinase-associated protein 2, SKP2_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
Mitotic G1 phase and G1/S transition (Homo sapiens)
G1 Phase (Homo sapiens)
Cyclin D associated events in G1 (Homo sapiens)
Phosphorylated p130 (RBL2) binds SCF(Skp2):Cks1 complex (Homo sapiens)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
SKP2 [nucleoplasm] (Homo sapiens)
p-T401,S672,1035-RBL2:SCF(Skp2):Cks1 [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
SKP2 [nucleoplasm] (Homo sapiens)
Ubiquitination of p130 (RBL2) by SCF (Skp2) (Homo sapiens)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
SKP2 [nucleoplasm] (Homo sapiens)
p-T401,S672,1035-RBL2:SCF(Skp2):Cks1 [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
SKP2 [nucleoplasm] (Homo sapiens)
G1/S Transition (Homo sapiens)
Cyclin E associated events during G1/S transition (Homo sapiens)
SCF(Skp2)-mediated degradation of p27/p21 (Homo sapiens)
Association of Cks1 with SCF(Skp2) complex (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
SKP2 [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
SKP2 [nucleoplasm] (Homo sapiens)
Binding of phospho-p27/p21:Cdk2:Cyclin E/A to the SCF(Skp2):Cks1 complex (Homo sapiens)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
SKP2 [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
SKP2 [nucleoplasm] (Homo sapiens)
SKP2 [nucleoplasm] (Homo sapiens)
Degradation of ubiquitinated p27/p21 by the 26S proteasome (Homo sapiens)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
SKP2 [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B:3xubiquitin [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
SKP2 [nucleoplasm] (Homo sapiens)
Ubiquitination of phospho-p27/p21 (Homo sapiens)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
SKP2 [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
SKP2 [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B:3xubiquitin [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
SKP2 [nucleoplasm] (Homo sapiens)
Regulation of mitotic cell cycle (Homo sapiens)
APC/C-mediated degradation of cell cycle proteins (Homo sapiens)
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Homo sapiens)
APC/C:Cdh1 polyubiquitinates SKP2 (Homo sapiens)
RB1:SKP2:APC/C:Cdh1 [nucleoplasm] (Homo sapiens)
SKP2 [nucleoplasm] (Homo sapiens)
RB1 recruits APC/C:Cdh1 complex to SKP2 (Homo sapiens)
RB1:SKP2:APC/C:Cdh1 [nucleoplasm] (Homo sapiens)
SKP2 [nucleoplasm] (Homo sapiens)
SKP2 [nucleoplasm] (Homo sapiens)
S Phase (Homo sapiens)
Cyclin A:Cdk2-associated events at S phase entry (Homo sapiens)
SCF(Skp2)-mediated degradation of p27/p21 (Homo sapiens)
Association of Cks1 with SCF(Skp2) complex (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
SKP2 [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
SKP2 [nucleoplasm] (Homo sapiens)
Binding of phospho-p27/p21:Cdk2:Cyclin E/A to the SCF(Skp2):Cks1 complex (Homo sapiens)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
SKP2 [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
SKP2 [nucleoplasm] (Homo sapiens)
SKP2 [nucleoplasm] (Homo sapiens)
Degradation of ubiquitinated p27/p21 by the 26S proteasome (Homo sapiens)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
SKP2 [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B:3xubiquitin [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
SKP2 [nucleoplasm] (Homo sapiens)
Ubiquitination of phospho-p27/p21 (Homo sapiens)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
SKP2 [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
SKP2 [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B:3xubiquitin [nucleoplasm] (Homo sapiens)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
SKP2 [nucleoplasm] (Homo sapiens)
Synthesis of DNA (Homo sapiens)
Switching of origins to a post-replicative state (Homo sapiens)
Orc1 removal from chromatin (Homo sapiens)
Phosphorylated Orc1 is ubiquitinated while still associated with chromatin (Homo sapiens)
SCF (SKP2) complex [nucleoplasm] (Homo sapiens)
SKP2 [nucleoplasm] (Homo sapiens)
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to chemical stress (Homo sapiens)
KEAP1-NFE2L2 pathway (Homo sapiens)
Regulation of BACH1 activity (Homo sapiens)
BACH1:FBXL17 binds SCF(SKP2) complex (Homo sapiens)
BACH1:FBXL17:SCF (SKP2) [nucleoplasm] (Homo sapiens)
SCF (SKP2) complex [nucleoplasm] (Homo sapiens)
SKP2 [nucleoplasm] (Homo sapiens)
SCF (SKP2) complex [nucleoplasm] (Homo sapiens)
SKP2 [nucleoplasm] (Homo sapiens)
FBXL17 ubiquitinates BACH1 (in BACH1:FBXL17:SCF (SKP2)) (Homo sapiens)
BACH1:FBXL17:SCF (SKP2) [nucleoplasm] (Homo sapiens)
SCF (SKP2) complex [nucleoplasm] (Homo sapiens)
SKP2 [nucleoplasm] (Homo sapiens)
SCF (SKP2) complex [nucleoplasm] (Homo sapiens)
SKP2 [nucleoplasm] (Homo sapiens)
DNA Replication (Homo sapiens)
Synthesis of DNA (Homo sapiens)
Switching of origins to a post-replicative state (Homo sapiens)
Orc1 removal from chromatin (Homo sapiens)
Phosphorylated Orc1 is ubiquitinated while still associated with chromatin (Homo sapiens)
SCF (SKP2) complex [nucleoplasm] (Homo sapiens)
SKP2 [nucleoplasm] (Homo sapiens)
Disease (Homo sapiens)
Diseases of mitotic cell cycle (Homo sapiens)
Aberrant regulation of mitotic cell cycle due to RB1 defects (Homo sapiens)
Aberrant regulation of mitotic exit in cancer due to RB1 defects (Homo sapiens)
Defective RB1 does not form a complex with SKP2 and FZR1 (Homo sapiens)
SKP2 [nucleoplasm] (Homo sapiens)
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional regulation by RUNX2 (Homo sapiens)
Regulation of RUNX2 expression and activity (Homo sapiens)
SCF(SKP2) complex binds RUNX2 (Homo sapiens)
RUNX2:SCF(SKP2) [nucleoplasm] (Homo sapiens)
SCF (SKP2) complex [nucleoplasm] (Homo sapiens)
SKP2 [nucleoplasm] (Homo sapiens)
SCF (SKP2) complex [nucleoplasm] (Homo sapiens)
SKP2 [nucleoplasm] (Homo sapiens)
SCF(SKP2) polyubiquitinates RUNX2 (Homo sapiens)
RUNX2:SCF(SKP2) [nucleoplasm] (Homo sapiens)
SCF (SKP2) complex [nucleoplasm] (Homo sapiens)
SKP2 [nucleoplasm] (Homo sapiens)
SCF (SKP2) complex [nucleoplasm] (Homo sapiens)
SKP2 [nucleoplasm] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Deubiquitination (Homo sapiens)
Ub-specific processing proteases (Homo sapiens)
USP13 binds UFD1L:SKP2 (Homo sapiens)
UFD1L:SKP2 [nucleoplasm] (Homo sapiens)
SKP2 [nucleoplasm] (Homo sapiens)
USP13:UFD1L:SKP2 [nucleoplasm] (Homo sapiens)
UFD1L:SKP2 [nucleoplasm] (Homo sapiens)
SKP2 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q13309 SKP2
Gene Names
SKP2, FBXL1
Chain
chain:1-424
Reference Genes
BioGPS Gene:6502 SKP2
COSMIC (genes):SKP2 SKP2
CTD Gene:6502 SKP2
dbSNP Gene:6502 SKP2
ENSEMBL:ENSG00000145604 SKP2
ENSEMBL_homo_sapiens_GENE:ENSG00000145604.17 SKP2
HGNC:10901 SKP2
KEGG Gene (Homo sapiens):6502 SKP2
Monarch:6502 SKP2
NCBI Gene:6502 SKP2
OMIM:601436 SKP2
UCSC:Q13309 SKP2
Reference Transcript
RefSeq:NM_005983.3 SKP2
RefSeq:NM_032637.3 SKP2
RefSeq:NM_001243120.1 SKP2
Other Identifiers
11739144_a_at
11760241_a_at
16984032
1941_at
203625_PM_x_at
203625_x_at
203626_PM_s_at
203626_s_at
210567_PM_s_at
210567_s_at
211042_PM_x_at
211042_x_at
2651085
2806519
2806520
2806522
2806523
2806528
2806529
2806530
2806531
2806532
2806534
2806536
2806544
2806545
2806546
43055_at
6502
8104912
A_14_P134273
A_23_P156310
GE59094
GO:0000082
GO:0000086
GO:0000209
GO:0000278
GO:0002376
GO:0005515
GO:0005634
GO:0005654
GO:0005730
GO:0005737
GO:0005829
GO:0006511
GO:0012501
GO:0016567
GO:0019005
GO:0023052
GO:0030163
GO:0031146
GO:0033148
GO:0036211
GO:0042802
GO:0042981
GO:0043161
GO:0043226
GO:0045087
GO:0051607
GO:0051726
GO:0070936
GO:0098542
GO:1902916
HMNXSV003042493
ILMN_1665538
ILMN_1791002
ILMN_1801391
PH_hs_0002055
PH_hs_0035392
TC05000161.hg
U33761_at
g12655170_3p_a_at
g12655170_3p_s_at
g5174684_3p_a_at
Participates
as a component of
UFD1L:SKP2 [nucleoplasm] (Homo sapiens)
SCF (SKP2) complex [nucleoplasm] (Homo sapiens)
RB1:SKP2:APC/C:Cdh1 [nucleoplasm] (Homo sapiens)
CUL1:SKP1:SKP2 [nucleoplasm] (Homo sapiens)
as an input of
Defective RB1 does not form a complex with SKP2 and FZR1 (Homo sapiens)
RB1 recruits APC/C:Cdh1 complex to SKP2 (Homo sapiens)
Other forms of this molecule
SKP2 [cytosol]
PolyUb-SKP2 [nucleoplasm]
Inferred To
Skp2 [nucleoplasm]
(Drosophila melanogaster)
Skp2 [nucleoplasm]
(Mus musculus)
Skp2 [nucleoplasm]
(Rattus norvegicus)
Ghost homologue of SKP2 [nucleoplasm]
(Canis familiaris)
Ghost homologue of SKP2 [nucleoplasm]
(Danio rerio)
Ghost homologue of SKP2 [nucleoplasm]
(Dictyostelium discoideum)
Ghost homologue of SKP2 [nucleoplasm]
(Saccharomyces cerevisiae)
Ghost homologue of SKP2 [nucleoplasm]
(Schizosaccharomyces pombe)
Ghost homologue of SKP2 [nucleoplasm]
(Xenopus tropicalis)
SKP2 [nucleoplasm]
(Bos taurus)
SKP2 [nucleoplasm]
(Gallus gallus)
SKP2 [nucleoplasm]
(Sus scrofa)
skpt-1 [nucleoplasm]
(Caenorhabditis elegans)
Cross References
RefSeq
NP_001230049.1
,
NP_005974.2
,
NP_116026.1
Guide to Pharmacology - Targets
3235
OpenTargets
ENSG00000145604
HPA
ENSG00000145604-SKP2
GeneCards
Q13309
Ensembl
ENST00000274254
,
ENST00000274255
,
ENSP00000274255
,
ENSG00000145604
,
ENSP00000274254
PRO
Q13309
Pharos - Targets
Q13309
PDB
8BYL
,
7B5M
,
8CDJ
,
8OR0
,
8OR3
,
7LUO
,
1FQV
,
8BYA
,
1FS1
,
2ASS
,
7ZBZ
,
7Z8T
,
7Z8V
,
1LDK
,
8CDK
,
2AST
,
8OR4
,
1FS2
,
7B5L
,
7B5R
,
7ZBW
Interactors (44)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P63208 SKP1
2
SKP1 [nucleoplasm]
(R-HSA-187538)
SKP1 [cytosol]
(R-HSA-174150)
0.952
18
UniProt:P24941 CDK2
5
p-Y15-CDK2 [nucleoplasm]
(R-HSA-187905)
p-CDK2 [nucleoplasm]
(R-HSA-68370)
CDK2 [cytosol]
(R-HSA-157440)
CDK2 [nucleoplasm]
(R-HSA-68365)
p-T160-CDK2 [nucleoplasm]
(R-HSA-187967)
0.892
12
UniProt:P61024 CKS1B
1
CKS1B [nucleoplasm]
(R-HSA-187533)
0.858
9
UniProt:Q13616 CUL1
3
G76-NEDD8-K720-CUL1 [cytosol]
(R-HSA-8952519)
CUL1 [nucleoplasm]
(R-HSA-187551)
CUL1 [cytosol]
(R-HSA-174230)
0.823
15
UniProt:P46527 CDKN1B
8
p-S10 CDKN1B [cytosol]
(R-HSA-9632829)
p-S10 CDKN1B [nucleoplasm]
(R-HSA-9632832)
p-T157-CDKN1B [cytosol]
(R-HSA-198629)
CDKN1B [cytosol]
(R-HSA-198622)
p-Y88-CDKN1B [cytosol]
(R-HSA-8848438)
p-Y88-CDKN1B [nucleoplasm]
(R-HSA-8942808)
p-T187-CDKN1B [nucleoplasm]
(R-HSA-187525)
CDKN1B [nucleoplasm]
(R-HSA-182563)
0.75
4
UniProt:P38936 CDKN1A
5
p-T145-CDKN1A [cytosol]
(R-HSA-198614)
p-Y77-CDKN1A [cytosol]
(R-HSA-8942601)
CDKN1A [cytosol]
(R-HSA-182512)
CDKN1A [nucleoplasm]
(R-HSA-182585)
p-S130-CDKN1A [nucleoplasm]
(R-HSA-187857)
0.731
4
UniProt:Q7L5N1 COPS6
2
COPS6 [nucleoplasm]
(R-HSA-5697026)
COPS6 [cytosol]
(R-HSA-416961)
0.725
7
UniProt:P06493 CDK1
11
CDK1 [endoplasmic reticulum membrane]
(R-HSA-264424)
p-Y4-CDK1 [cytosol]
(R-HSA-9836187)
p-T14,T161-CDK1 [nucleoplasm]
(R-HSA-170078)
p-T14-CDK1 [nucleoplasm]
(R-HSA-170045)
p-T14-CDK1 [cytosol]
(R-HSA-170064)
CDK1 [nucleoplasm]
(R-HSA-68889)
CDK1 [cytosol]
(R-HSA-170075)
p-T14,Y15,T161-CDK1 [cytosol]
(R-HSA-170071)
p-T161-CDK1 [cytosol]
(R-HSA-157415)
p-T14,Y15,T161-CDK1 [nucleoplasm]
(R-HSA-170074)
p-T161-CDK1 [nucleoplasm]
(R-HSA-170066)
0.725
6
UniProt:P20248 CCNA2
3
PolyUb-CCNA2 [nucleoplasm]
(R-HSA-6783099)
CCNA2 [cytosol]
(R-HSA-157444)
CCNA2 [nucleoplasm]
(R-HSA-68905)
0.725
6
UniProt:Q00526 CDK3
0.643
4
UniProt:P62877 RBX1
2
RBX1 [nucleoplasm]
(R-HSA-1234142)
RBX1 [cytosol]
(R-HSA-180582)
0.623
4
UniProt:P11440 Cdk1
11
phospho-p-T161-CDK1 [nucleoplasm]
(R-MMU-170066)
phospho-p-T14,Y15,T161-CDK1 [nucleoplasm]
(R-MMU-170074)
phospho-p-T161-CDK1 [cytosol]
(R-MMU-157415)
phospho-p-T14,Y15,T161-CDK1 [cytosol]
(R-MMU-170071)
CDK1 [cytosol]
(R-MMU-170075)
phospho-p-T14-CDK1 [cytosol]
(R-MMU-170064)
phospho-p-T14-CDK1 [nucleoplasm]
(R-MMU-170045)
Cdk1 [nucleoplasm]
(R-MMU-1362302)
phospho-p-T14,T161-CDK1 [nucleoplasm]
(R-MMU-170078)
phospho-p-Y4-CDK1 [cytosol]
(R-MMU-9836187)
CDK1 [endoplasmic reticulum membrane]
(R-MMU-264424)
0.623
4
UniProt:Q13309 SKP2
3
SKP2 [cytosol]
(R-HSA-975495)
PolyUb-SKP2 [nucleoplasm]
(R-HSA-9687073)
SKP2 [nucleoplasm]
(R-HSA-975554)
0.591
3
UniProt:P28562 DUSP1
1
DUSP1 [nucleoplasm]
(R-HSA-203796)
0.576
3
UniProt:Q9NTG7 SIRT3
2
SIRT3 [nucleoplasm]
(R-HSA-9622879)
SIRT3(?-399) [mitochondrial matrix]
(R-HSA-1605416)
0.576
5
UniProt:Q9UM11 FZR1
4
FZR1 [cytosol]
(R-HSA-174249)
FZR1 [nucleoplasm]
(R-HSA-174099)
p-FZR1 [nucleoplasm]
(R-HSA-174257)
p-FZR1 [cytosol]
(R-HSA-174193)
0.564
4
UniProt:Q6DN90 IQEC1
0.527
3
UniProt:Q9UBW8 COPS7A
2
COPS7A [nucleoplasm]
(R-HSA-5697011)
COPS7A [cytosol]
(R-HSA-416964)
0.527
2
UniProt:P12268 IMPDH2
4
IMPDH2 [secretory granule lumen]
(R-HSA-6803323)
IMPDH2 [extracellular region]
(R-HSA-6806455)
IMPDH2 [ficolin-1-rich granule lumen]
(R-HSA-6803330)
IMPDH2 [cytosol]
(R-HSA-57350)
0.527
2
UniProt:Q9H9A6 LRC40
0.527
3
UniProt:P31321 PRKAR1B
2
PRKAR1B [cytosol]
(R-HSA-57838)
PRKAR1B [ciliary base]
(R-HSA-5610409)
0.527
2
UniProt:Q2VPB7 AP5B1
0.527
3
UniProt:Q5VUJ6 LRCH2
0.527
2
UniProt:Q9H1A4 ANAPC1
2
ANAPC1 [cytosol]
(R-HSA-174189)
ANAPC1 [nucleoplasm]
(R-HSA-174217)
0.527
3
UniProt:P0CI25 TRI49
0.527
2
UniProt:O14531 DPYSL4
3
p-Y-DPYSL4 [cytosol]
(R-HSA-399794)
DPYSL4 [cytosol]
(R-HSA-398126)
p-S544-DPYSL4 [cytosol]
(R-HSA-399808)
0.527
2
UniProt:Q96BY7 ATG2B
0.527
2
UniProt:Q92905 COPS5
2
COPS5 [nucleoplasm]
(R-HSA-5697019)
COPS5 [cytosol]
(R-HSA-416963)
0.527
3
UniProt:Q9BZL6 PRKD2
1
PRKD2 [cytosol]
(R-HSA-58214)
0.527
2
UniProt:Q6ZRV2 FA83H
0.527
3
UniProt:Q8N5M4 TTC9C
0.527
4
UniProt:Q9BV68 RNF126
1
RNF126 [cytosol]
(R-HSA-8851642)
0.527
2
UniProt:Q6PJI9 WDR59
1
WDR59 [lysosomal membrane]
(R-HSA-9638236)
0.527
3
UniProt:Q6SPF0 SAMD1
0.527
3
UniProt:Q12834 CDC20
3
CDC20 [cytosol]
(R-HSA-141412)
CDC20 [nucleoplasm]
(R-HSA-174112)
PolyUb-CDC20 [nucleoplasm]
(R-HSA-6783069)
0.527
3
UniProt:Q13188 STK3
4
p-T180-STK3(1-322) [cytosol]
(R-HSA-2028696)
STK3(323-491) [cytosol]
(R-HSA-2028684)
STK3(1-491) [cytosol]
(R-HSA-2028280)
p-T180-STK3(1-491) [cytosol]
(R-HSA-2028274)
0.527
2
UniProt:O75496 GMNN
2
GMNN [nucleoplasm]
(R-HSA-113554)
PolyUb-GMNN [nucleoplasm]
(R-HSA-68585)
0.527
2
UniProt:Q9Y2Z0 SUGT1
1
SUGT1 [cytosol]
(R-HSA-874107)
0.527
3
UniProt:P0CG47 UBB
20
UBB(77-152) [endocytic vesicle membrane]
(R-HSA-939253)
UBB(1-76) [endocytic vesicle membrane]
(R-HSA-939231)
UBB(153-228) [endocytic vesicle membrane]
(R-HSA-939171)
Ub-33-UBB(1-76) [mitochondrial outer membrane]
(R-HSA-6783023)
Ub-109-UBB(77-152) [mitochondrial outer membrane]
(R-HSA-6783008)
Ub-185-UBB(153-228) [mitochondrial outer membrane]
(R-HSA-6783046)
Ub-215-UBB(153-228) [mitochondrial outer membrane]
(R-HSA-6783002)
Ub-63-UBB(1-76) [mitochondrial outer membrane]
(R-HSA-6783148)
Ub-139-UBB(77-152) [mitochondrial outer membrane]
(R-HSA-6783012)
Ub-158-UBB(153-228) [mitochondrial outer membrane]
(R-HSA-6783162)
Ub-6-UBB(1-76) [mitochondrial outer membrane]
(R-HSA-6783014)
Ub-82-UBB(77-152) [mitochondrial outer membrane]
(R-HSA-6783015)
Ub-163-UBB(153-228) [mitochondrial outer membrane]
(R-HSA-6783025)
Ub-87-UBB(77-152) [mitochondrial outer membrane]
(R-HSA-6782998)
Ub-11-UBB(1-76) [mitochondrial outer membrane]
(R-HSA-6783109)
Ub-124-UBB(77-152) [mitochondrial outer membrane]
(R-HSA-6783131)
Ub-200-UBB(153-228) [mitochondrial outer membrane]
(R-HSA-6783100)
Ub-48-UBB(1-76) [mitochondrial outer membrane]
(R-HSA-6783165)
Ub-181-UBB(153-228) [mitochondrial outer membrane]
(R-HSA-6783160)
Ub-29-UBB(1-76) [mitochondrial outer membrane]
(R-HSA-6783070)
0.527
2
UniProt:Q9H211 CDT1
1
CDT1 [nucleoplasm]
(R-HSA-68536)
0.527
2
UniProt:Q4AE16 Q4AE16
0.524
3
UniProt:Q09472 EP300
5
monoSUMO1-K1020,1024-EP300 [nucleoplasm]
(R-HSA-3899306)
Foxo4-S-S-EP300 [nucleoplasm]
(R-HSA-9617720)
FOXO4-S-S-EP300 [nucleoplasm]
(R-HSA-9617691)
p-S,T-EP300 [nucleoplasm]
(R-HSA-8878072)
EP300 [nucleoplasm]
(R-HSA-381325)
0.524
3
UniProt:P09803 Cdh1
6
CDH1(155-700) [plasma membrane]
(R-MMU-2534244)
CDH1(701-882) [extracellular region]
(R-MMU-2534158)
Cdh1(157-884) [plasma membrane]
(R-MMU-199081)
CDH1(155-750) [plasma membrane]
(R-MMU-202940)
CDH1(751-882) [plasma membrane]
(R-MMU-202929)
CDH1(155-882) [plasma membrane]
(R-MMU-198003)
0.524
2
UniProt:Q13415 ORC1
5
ORC1 [nucleoplasm]
(R-HSA-68522)
ORC1 [cytosol]
(R-HSA-113840)
p-S,T-ORC1 [nucleoplasm]
(R-HSA-68943)
PolyUb,p-S,T-ORC1 [nucleoplasm]
(R-HSA-9032189)
PolyUb,p-S,T-ORC1 [cytosol]
(R-HSA-9032195)
0.524
2
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