AXIN1 E406* [cytosol]

Stable Identifier
R-HSA-5251500
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
AXIN1 E406* [cytosol] icon
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
10700176 AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1

Satoh, S, Daigo, Y, Furukawa, Y, Kato, T, Miwa, N, Nishiwaki, T, Kawasoe, T, Ishiguro, H, Fujita, M, Tokino, T, Sasaki, Y, Imaoka, S, Murata, M, Shimano, T, Yamaoka, Y, Nakamura, Y

Nat. Genet. 2000
External Reference Information
External Reference
Gene Names
AXIN1, AXIN
Chain
chain:1-862
Other Identifiers
0002480053
0002970068
11754511_a_at
16822408
212849_at
33319_at
3675048
3675049
3675051
3675053
3675055
3675056
3675057
3675058
3675059
3675062
3675066
3675069
3675070
3675090
3675091
3675092
7998211
8312
AF009674_at
GE61790
GO:0001934
GO:0003674
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005737
GO:0005829
GO:0005886
GO:0006464
GO:0006915
GO:0006950
GO:0007165
GO:0007267
GO:0007275
GO:0008013
GO:0008150
GO:0008219
GO:0009056
GO:0009058
GO:0010800
GO:0016020
GO:0016055
GO:0016328
GO:0019899
GO:0019901
GO:0022607
GO:0030111
GO:0030674
GO:0030877
GO:0031398
GO:0031410
GO:0031625
GO:0032147
GO:0032991
GO:0033138
GO:0033146
GO:0034622
GO:0034641
GO:0035591
GO:0042802
GO:0042803
GO:0043226
GO:0045732
GO:0045893
GO:0046330
GO:0046332
GO:0048471
GO:0048856
GO:0051443
GO:0060090
GO:0065003
GO:0070016
GO:0070411
GO:0071944
GO:0090090
GO:0090263
GO:1904885
GO:1904886
GO:2000060
Hs.184434.0.S1_3p_at
ILMN_1692967
ILMN_1766185
PH_hs_0026858
TC16000725.hg
Participant Of
Other forms of this molecule
Modified Residues
Name
L-glutamic acid 406 replaced with unknown
Coordinate
406
PsiMod
A protein modification that effectively removes or replaces an L-glutamic acid.
Disease
Name Identifier Synonyms
cancer 162 malignant tumor, malignant neoplasm, primary cancer
hepatocellular carcinoma 684 adult Hepatoma, adult primary Liver carcinoma, Liver carcinoma, Hepatocellular carcinoma (morphologic abnormality), primary carcinoma of liver (disorder), hepatoma, Hepatoma, adult primary hepatocellular carcinoma, primary carcinoma of the liver cells, Hepatocellular carcinoma (clinical), Liver carcinoma, HCC, carcinoma of liver, specified as primary
Interactors (63)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P49841 GSK3B  4 0.974 50
 UniProt:P35222 CTNNB1  33 0.94 44
 UniProt:P25054 APC  86 0.725 15
 UniProt:O15169 AXIN1  11 0.709 4
 UniProt:Q5JTC6 AMER1  5 0.708 7
 UniProt:P49674 CSNK1E  2 0.687 5
 UniProt:P49840 GSK3A  3 0.669 3
 UniProt:P14923 JUP  5 0.666 4
 UniProt:P67775 PPP2CA  4 0.643 4
 UniProt:P48729 CSNK1A1  2 0.643 4
 UniProt:Q9H7D7 WDR26      0.641 4
 UniProt:P01106 MYC  2 0.623 10
 UniProt:O14641 DVL2  5 0.59 3
 UniProt:Q9UKB1 FBXW11  1 0.558 4
 UniProt:Q9BQ66 KR412      0.556 3
 UniProt:Q99750 MDFI      0.556 3
 UniProt:Q96KG9-4 SCYL1      0.556 3
 UniProt:O94972 TRIM37  1 0.556 3
 UniProt:Q9C019 TRI15      0.556 3
 UniProt:Q9UJV3-2 MID2      0.556 3
 UniProt:Q969G2 LHX4  1 0.556 3
 IntAct:EBI-16436498 CCSB ORF ID      0.556 3
 UniProt:Q9BYR5 KRTAP4-2  1 0.556 3
 UniProt:Q9H257-2 CARD9      0.556 3
 UniProt:Q13137 CACO2      0.556 3
 UniProt:Q5JR59-3 MTUS2      0.556 3
 UniProt:O43586 PSTPIP1  1 0.556 3
 IntAct:EBI-16436244 CCSB ORF ID      0.556 3
 IntAct:EBI-16434222 CCSB ORF ID      0.556 3
 UniProt:O75558 STX11      0.556 3
 UniProt:Q96K21-3 ZFYVE19      0.556 3
 UniProt:Q2TAC2-2 CCDC57      0.556 3
 IntAct:EBI-16437007 CCSB ORF ID      0.556 3
 UniProt:Q9UBB9 TFIP11  1 0.556 3
 IntAct:EBI-16429620 CCSB ORF ID      0.556 3
 UniProt:Q15654 TRIP6      0.556 6
 UniProt:Q9HCK0 ZBT26      0.556 3
 UniProt:G2XKQ0 SUMO5      0.556 3
 UniProt:Q6FHY5 Q6FHY5      0.556 3
 UniProt:Q6A162 KRT40  1 0.556 3
 UniProt:P14373 TRIM27  2 0.556 3
 UniProt:P63165 SUMO1  155 0.556 3
 UniProt:O15105 SMAD7  2 0.556 8
 UniProt:Q08379 GOLGA2  3 0.556 3
 UniProt:Q12933 TRAF2  5 0.556 3
 UniProt:O75581 LRP6  8 0.527 9
 UniProt:Q93008 USP9X  1 0.527 2
 IntAct:EBI-11789122 GSK3A      0.525 2
 UniProt:G1T8E2 G1T8E2      0.525 2
 UniProt:Q92837 FRAT1  1 0.525 3
 UniProt:Q5VWQ8-2 DAB2IP      0.524 2
 UniProt:P62136 PPP1CA  1 0.524 4
 UniProt:P04637 TP53  27 0.524 4
 UniProt:P23258 TUBG1  1 0.512 4
 UniProt:Q14194 CRMP1  4 0.508 2
 UniProt:P39687 ANP32A  1 0.508 2
 UniProt:Q15583 TGIF1  1 0.499 4
 UniProt:Q60953-2 PML      0.499 2
 UniProt:P46937 YAP1  7 0.499 11
 UniProt:P35813 PPM1A  2 0.499 2
 UniProt:P49407 ARRB1  5 0.499 2
 UniProt:Q99ML9 Rnf111  3 0.463 5
 UniProt:P29590 PML  5 0.463 2
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