ub-AXIN1 [cytosol]

Stable Identifier
R-HSA-4641133
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Icon
ub-AXIN1 [cytosol] icon
ub-AXIN1 [cytosol] icon
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:O15169 AXIN1
Gene Names
AXIN1, AXIN
Chain
chain:1-862
Reference Genes
BioGPS Gene:8312 AXIN1
COSMIC (genes):AXIN1 AXIN1
CTD Gene:8312 AXIN1
dbSNP Gene:8312 AXIN1
ENSEMBL:ENSG00000103126 AXIN1
HGNC:903 AXIN1
KEGG Gene (Homo sapiens):8312 AXIN1
Monarch:8312 AXIN1
NCBI Gene:8312 AXIN1
OMIM:603816 AXIN1
UCSC:O15169 AXIN1
Reference Transcript
Other Identifiers
0002480053
0002970068
11754511_a_at
12987
16822408
1DK8
1EMU
1O9U
212849_at
33319_at
3675048
3675049
3675051
3675053
3675055
3675056
3675057
3675058
3675059
3675062
3675066
3675069
3675070
3675090
3675091
3675092
3ZDI
4B7T
4NM0
4NM3
4NM5
4NM7
4NU1
5WZZ
7998211
8312
A0A0S2Z4R0
A0A0S2Z4S3
AAC51624
AAH17447
AAH44648
AAK61224
AC005202
AE006463
AF009674
AF009674_at
ALQ33871
ALQ33872
AXIN1
AXIN1-201
AXIN1-202
BC017447
BC044648
CAB012987
CAI95589
CAI95590
CAI95600
CAI95601
CCDS10405
CCDS10406
CH471112
EAW85835
EAW85836
ENSG00000103126
ENSP00000262320
ENSP00000346935
ENST00000262320
ENST00000262320.7
ENST00000354866
ENST00000354866.7
EntrezGene:8312
EntrezGene:AXIN1
GE61790
GO:0001934
GO:0003674
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005737
GO:0005829
GO:0005886
GO:0006464
GO:0006915
GO:0006950
GO:0007165
GO:0007267
GO:0007275
GO:0008013
GO:0008150
GO:0008219
GO:0009056
GO:0009058
GO:0010800
GO:0016020
GO:0016055
GO:0016328
GO:0019899
GO:0019901
GO:0022607
GO:0030111
GO:0030159
GO:0030674
GO:0030877
GO:0031398
GO:0031410
GO:0031625
GO:0032147
GO:0032991
GO:0033138
GO:0033146
GO:0034622
GO:0034641
GO:0035591
GO:0042802
GO:0042803
GO:0043226
GO:0045732
GO:0045893
GO:0046330
GO:0046332
GO:0048471
GO:0048856
GO:0051443
GO:0060090
GO:0065003
GO:0070016
GO:0070411
GO:0071944
GO:0090090
GO:0090263
GO:1904885
GO:1904886
GO:2000060
HGNC:903
Hs.184434.0.S1_3p_at
ILMN_1692967
ILMN_1766185
IPR001158
IPR014936
IPR016137
IPR024066
IPR029071
IPR029797
IPR032101
IPR036305
IPR038207
KU178413
KU178414
MIM:114550
MIM:603816
MIM:607864
NM_003502
NM_181050
NP_003493
NP_851393
NR_134879
PF00615
PF00778
PF08833
PF16646
PH_hs_0026858
PR01301
SM00021
SM00315
TC16000725.hg
UPI000000DAA7
UPI000012669E
XM_011522682
XM_011522683
XM_011522684
XM_011522686
XM_017023743
XM_017023744
XM_017023745
XM_017023746
XP_011520984
XP_011520985
XP_011520986
XP_011520988
XP_016879232
XP_016879233
XP_016879234
XP_016879235
Z69667
Z99754
Participant Of
hasMember
Other forms of this molecule
AXIN1 L396M [cytosol]
AXIN1 Y346* [cytosol]
AXIN1 E406* [cytosol]
AXIN1 [cytosol]
p-T519,S524,S531-AXIN1 [cytosol]
Ub-RibC-AXIN1 [cytosol]
RibC-AXIN1 [cytosol]
AXIN1 P255S [cytosol]
AXIN1 P354L [cytosol]
AXIN1 W247* [cytosol]
Inferred To
ub-AXIN1 [cytosol] (Danio rerio)
ub-AXIN1 [cytosol] (Drosophila melanogaster)
ub-AXIN1 [cytosol] (Mus musculus)
ub-AXIN1 [cytosol] (Sus scrofa)
ub-AXIN1 [cytosol] (Xenopus tropicalis)
Modified Residues
Name
ubiquitinylated lysine (K48polyUb [cytosol]) at 505
Coordinate
505
Modification
K48polyUb [cytosol]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
RefSeq
OpenTargets
GeneCards
PRO
Orphanet
PDB
Interactors (63)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P49841 GSK3B  4 0.974 50
 UniProt:P35222 CTNNB1  24 0.94 44
 UniProt:P25054 APC  13 0.725 15
 UniProt:O15169 AXIN1  11 0.709 4
 UniProt:Q5JTC6 AMER1  3 0.708 7
 UniProt:P49674 CSNK1E  2 0.687 5
 UniProt:P49840 GSK3A  2 0.669 3
 UniProt:P14923 JUP  5 0.666 4
 UniProt:P67775 PPP2CA  4 0.643 4
 UniProt:P48729 CSNK1A1  2 0.643 4
 UniProt:Q9H7D7 WDR26      0.641 4
 UniProt:P01106 MYC  2 0.623 10
 UniProt:O14641 DVL2  5 0.59 3
 UniProt:Q9UKB1 FBXW11  1 0.558 4
 UniProt:Q9BQ66 KR412      0.556 3
 UniProt:Q99750 MDFI      0.556 3
 UniProt:Q96KG9-4 SCYL1      0.556 3
 UniProt:O94972 TRIM37  1 0.556 3
 UniProt:Q9C019 TRI15      0.556 3
 UniProt:Q9UJV3-2 MID2      0.556 3
 UniProt:Q969G2 LHX4  1 0.556 3
 IntAct:EBI-16436498 CCSB ORF ID      0.556 3
 UniProt:Q9BYR5 KRTAP4-2  1 0.556 3
 UniProt:Q9H257-2 CARD9      0.556 3
 UniProt:Q13137 CACO2      0.556 3
 UniProt:Q5JR59-3 MTUS2      0.556 3
 UniProt:O43586 PSTPIP1  1 0.556 3
 IntAct:EBI-16436244 CCSB ORF ID      0.556 3
 IntAct:EBI-16434222 CCSB ORF ID      0.556 3
 UniProt:O75558 STX11      0.556 3
 UniProt:Q96K21-3 ZFYVE19      0.556 3
 UniProt:Q2TAC2-2 CCDC57      0.556 3
 IntAct:EBI-16437007 CCSB ORF ID      0.556 3
 UniProt:Q9UBB9 TFIP11  1 0.556 3
 IntAct:EBI-16429620 CCSB ORF ID      0.556 3
 UniProt:Q15654 TRIP6      0.556 6
 UniProt:Q9HCK0 ZBT26      0.556 3
 UniProt:G2XKQ0 SUMO5      0.556 3
 UniProt:Q6FHY5 Q6FHY5      0.556 3
 UniProt:Q6A162 KRT40  1 0.556 3
 UniProt:Q12933 TRAF2  5 0.556 3
 UniProt:P14373 TRIM27  2 0.556 3
 UniProt:P63165 SUMO1  155 0.556 3
 UniProt:O15105 SMAD7  2 0.556 8
 UniProt:Q08379 GOLGA2  3 0.556 3
 UniProt:Q93008 USP9X  1 0.527 2
 UniProt:O75581 LRP6  8 0.527 9
 IntAct:EBI-11789122 GSK3A      0.525 2
 UniProt:G1T8E2 G1T8E2      0.525 2
 UniProt:Q92837 FRAT1  1 0.525 3
 UniProt:Q5VWQ8-2 DAB2IP      0.524 2
 UniProt:P04637 TP53  27 0.524 4
 UniProt:P62136 PPP1CA  1 0.524 4
 UniProt:P23258 TUBG1  1 0.512 4
 UniProt:Q14194 CRMP1  4 0.508 2
 UniProt:P39687 ANP32A  1 0.508 2
 UniProt:P49407 ARRB1  5 0.499 2
 UniProt:P46937 YAP1  7 0.499 11
 UniProt:Q15583 TGIF1  1 0.499 4
 UniProt:Q60953-2 PML      0.499 2
 UniProt:P35813 PPM1A  2 0.499 2
 UniProt:Q99ML9 Rnf111  3 0.463 5
 UniProt:P29590 PML  5 0.463 2