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What is Reactome ?
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Team
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Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
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ORCID Integration Project
COVID-19 Disease Pathways
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Userguide
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Analysis Data
Analysis Gene Expression
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Icon Info
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Citing us
Tools
Pathway Browser
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Go!
ub-AXIN1 [cytosol]
Stable Identifier
R-HSA-4641133
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Icon
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by WNT (Homo sapiens)
TCF dependent signaling in response to WNT (Homo sapiens)
Degradation of AXIN (Homo sapiens)
AXIN is ubiquitinated by SMURF2 (Homo sapiens)
ub-AXIN:SMURF2 [cytosol] (Homo sapiens)
ub-AXIN [cytosol] (Homo sapiens)
ub-AXIN1 [cytosol] (Homo sapiens)
Ubiquitinated AXIN is degraded by the proteasome (Homo sapiens)
ub-AXIN:SMURF2 [cytosol] (Homo sapiens)
ub-AXIN [cytosol] (Homo sapiens)
ub-AXIN1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:O15169 AXIN1
Gene Names
AXIN1, AXIN
Chain
chain:1-862
Reference Genes
BioGPS Gene:8312 AXIN1
COSMIC (genes):AXIN1 AXIN1
CTD Gene:8312 AXIN1
dbSNP Gene:8312 AXIN1
ENSEMBL:ENSG00000103126 AXIN1
HGNC:903 AXIN1
KEGG Gene (Homo sapiens):8312 AXIN1
Monarch:8312 AXIN1
NCBI Gene:8312 AXIN1
OMIM:603816 AXIN1
UCSC:O15169 AXIN1
Reference Transcript
RefSeq:NM_003502.3 AXIN1
RefSeq:NM_181050.2 AXIN1
Other Identifiers
0002480053
0002970068
11754511_a_at
16822408
212849_at
33319_at
3675048
3675049
3675051
3675053
3675055
3675056
3675057
3675058
3675059
3675062
3675066
3675069
3675070
3675090
3675091
3675092
7998211
8312
AF009674_at
GE61790
GO:0001934
GO:0003674
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005737
GO:0005829
GO:0005886
GO:0006464
GO:0006915
GO:0006950
GO:0007165
GO:0007267
GO:0007275
GO:0008013
GO:0008150
GO:0008219
GO:0009056
GO:0009058
GO:0010800
GO:0016020
GO:0016055
GO:0016328
GO:0019899
GO:0019901
GO:0022607
GO:0030111
GO:0030159
GO:0030674
GO:0030877
GO:0031398
GO:0031410
GO:0031625
GO:0032147
GO:0032991
GO:0033138
GO:0033146
GO:0034622
GO:0034641
GO:0035591
GO:0042802
GO:0042803
GO:0043226
GO:0045732
GO:0045893
GO:0046330
GO:0046332
GO:0048471
GO:0048856
GO:0051443
GO:0060090
GO:0065003
GO:0070016
GO:0070411
GO:0071944
GO:0090090
GO:0090263
GO:1904885
GO:1904886
GO:2000060
HMNXSV003035039
HMNXSV003043314
Hs.184434.0.S1_3p_at
ILMN_1692967
ILMN_1766185
PH_hs_0026858
TC16000725.hg
Participates
as a member of
ub-AXIN [cytosol] (Homo sapiens)
Other forms of this molecule
AXIN1 L396M [cytosol]
AXIN1 Y346* [cytosol]
AXIN1 E406* [cytosol]
AXIN1 W247* [cytosol]
AXIN1 P354L [cytosol]
AXIN1 P255S [cytosol]
AXIN1 [cytosol]
p-T519,S524,S531-AXIN1 [cytosol]
RibC-AXIN1 [cytosol]
Ub-RibC-AXIN1 [cytosol]
Inferred To
axin1 [cytosol]
(Danio rerio)
Axn [cytosol]
(Drosophila melanogaster)
AXIN1 [cytosol]
(Canis familiaris)
AXIN1 [cytosol]
(Gallus gallus)
AXIN1 [cytosol]
(Sus scrofa)
Axin1 [cytosol]
(Mus musculus)
Modified Residues
Name
ubiquitinylated lysine (K48polyUb [cytosol]) at 505
Coordinate
505
Modification
K48polyUb [cytosol]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
RefSeq
NP_851393.1
,
NP_003493.1
OpenTargets
ENSG00000103126
HPA
ENSG00000103126-AXIN1
GeneCards
O15169
Ensembl
ENST00000262320
,
ENSP00000262320
,
ENSG00000103126
,
ENSP00000346935
,
ENST00000354866
PRO
O15169
Orphanet
24358
PDB
4NM7
,
4NM3
,
5WZZ
,
4B7T
,
1O9U
,
4NU1
,
4NM5
,
1EMU
,
4NM0
,
3ZDI
,
6JCK
,
1DK8
Interactors (64)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P49841 GSK3B
4
p-S9-GSK3B [cytosol]
(R-HSA-3149577)
GSK3B del304-316 [cytosol]
(R-HSA-5339682)
GSK3B [cytosol]
(R-HSA-2997551)
GSK3B [nucleoplasm]
(R-HSA-2022823)
0.974
50
UniProt:P35222 CTNNB1
33
CTNNB1 S45F [cytosol]
(R-HSA-4791268)
CTNNB1 S45A [cytosol]
(R-HSA-9663982)
CTNNB1 S45C [cytosol]
(R-HSA-9663983)
CTNNB1 S45Y [cytosol]
(R-HSA-9663975)
CTNNB1 S45N [cytosol]
(R-HSA-9663984)
CTNNB1 S45P [cytosol]
(R-HSA-4791272)
pT41,S45-CTNNB1 S37P [cytosol]
(R-HSA-9663981)
pT41,S45-CTNNB1 S37F [cytosol]
(R-HSA-4839621)
pT41,S45-CTNNB1 S37A [cytosol]
(R-HSA-4839619)
pT41,S45-CTNNB1 S37Y [cytosol]
(R-HSA-9663978)
pT41,S45-CTNNB1 S37C [cytosol]
(R-HSA-4839617)
pS37,T41,S45-CTNNB1 S33A [cytosol]
(R-HSA-9663976)
pS37,T41,S45-CTNNB1 S33T [cytosol]
(R-HSA-9663977)
pS37,T41,S45-CTNNB1 S33C [cytosol]
(R-HSA-4839630)
pS37,T41,S45-CTNNB1 S33F [cytosol]
(R-HSA-4839628)
pS37,T41,S45-CTNNB1 S33P [cytosol]
(R-HSA-4839626)
pS37,T41,S45-CTNNB1 S33Y [cytosol]
(R-HSA-4839625)
pS45-CTNNB1 T41N [cytosol]
(R-HSA-9663980)
pS45-CTNNB1 T41A [cytosol]
(R-HSA-4836868)
pS45-CTNNB1 T41I [cytosol]
(R-HSA-4839612)
Ub-K,p-Y-CTNNB1 [cytosol]
(R-HSA-8877006)
p-Y-CTNNB1 [cytosol]
(R-HSA-8876940)
p-S552-CTNNB1 [nucleoplasm]
(R-HSA-3134926)
p-S552-CTNNB1 [cytosol]
(R-HSA-3134933)
CTNNB1 [plasma membrane]
(R-HSA-9038440)
p-S45 CTNNB1 [cytosol]
(R-HSA-8942363)
p-T41,S45 CTNNB1 [cytosol]
(R-HSA-8942367)
p-S37,T41,S45, CTNNB1 [cytosol]
(R-HSA-8942369)
p-S33,S37,T41,S45 CTNNB1 [cytosol]
(R-HSA-8942374)
CTNNB1(116-376) [cytosol]
(R-HSA-202950)
CTNNB1(1-115) [cytosol]
(R-HSA-202930)
CTNNB1 [cytosol]
(R-HSA-448839)
CTNNB1 [nucleoplasm]
(R-HSA-3451168)
0.94
44
UniProt:P25054 APC
86
APC C1410* [cytosol]
(R-HSA-9666925)
APC R213* [cytosol]
(R-HSA-9666924)
APC K1310* [cytosol]
(R-HSA-9666926)
APC R499* [cytosol]
(R-HSA-9666927)
APC R1450* [cytosol]
(R-HSA-5251499)
APC G1357* [cytosol]
(R-HSA-9666940)
APC L1488* [cytosol]
(R-HSA-9666941)
APC S1400* [cytosol]
(R-HSA-9666942)
APC S1346* [cytosol]
(R-HSA-9666943)
APC R405* [cytosol]
(R-HSA-9666936)
APC S1281* [cytosol]
(R-HSA-9666937)
APC E1573* [cytosol]
(R-HSA-9666938)
APC R805* [cytosol]
(R-HSA-9666939)
APC R1386* [cytosol]
(R-HSA-9666932)
APC S1327* [cytosol]
(R-HSA-9666933)
APC E1209* [cytosol]
(R-HSA-9666934)
APC Q1469* [cytosol]
(R-HSA-9666935)
APC R564* [cytosol]
(R-HSA-9666928)
APC E1536* [cytosol]
(R-HSA-9666929)
APC G1288* [cytosol]
(R-HSA-9666930)
APC G1312* [cytosol]
(R-HSA-9666931)
APC R283* [cytosol]
(R-HSA-9666988)
APC Q1367* [cytosol]
(R-HSA-9666989)
APC E1353* [cytosol]
(R-HSA-9666990)
APC R332* [cytosol]
(R-HSA-9666991)
APC K993* [cytosol]
(R-HSA-9666984)
APC R876* [cytosol]
(R-HSA-9666985)
APC R302* [cytosol]
(R-HSA-9666986)
APC E1309* [cytosol]
(R-HSA-9666987)
APC Y935* [cytosol]
(R-HSA-9666980)
APC E1286* [cytosol]
(R-HSA-9666981)
APC Q1378* [cytosol]
(R-HSA-9666982)
APC R554* [cytosol]
(R-HSA-9666983)
APC S1356* [cytosol]
(R-HSA-9666976)
APC R232* [cytosol]
(R-HSA-9666977)
APC E1379* [cytosol]
(R-HSA-9666978)
APC E984* [cytosol]
(R-HSA-9666979)
APC R1114* [cytosol]
(R-HSA-9666996)
APC S1282* [cytosol]
(R-HSA-9666997)
APC Q1328* [cytosol]
(R-HSA-9666998)
APC E1295* [cytosol]
(R-HSA-9666992)
APC E1151* [cytosol]
(R-HSA-9666993)
APC E1322* [cytosol]
(R-HSA-9666994)
APC E1345* [cytosol]
(R-HSA-9666995)
APC K1308* [cytosol]
(R-HSA-9666956)
APC S1344* [cytosol]
(R-HSA-9666957)
APC E1577* [cytosol]
(R-HSA-9666958)
APC Q1127* [cytosol]
(R-HSA-9666959)
APC E1464* [cytosol]
(R-HSA-9666952)
APC E1317* [cytosol]
(R-HSA-9666953)
APC G1309Dfs*4 [cytosol]
(R-HSA-4791251)
APC W1049* [cytosol]
(R-HSA-9666954)
APC Q1429* [cytosol]
(R-HSA-9666955)
APC L1564* [cytosol]
(R-HSA-9666948)
APC Q1294* [cytosol]
(R-HSA-9666949)
APC K1363* [cytosol]
(R-HSA-9666950)
APC E1408* [cytosol]
(R-HSA-9666951)
APC E1284* [cytosol]
(R-HSA-9666944)
APC E1374* [cytosol]
(R-HSA-9666945)
APC Q767* [cytosol]
(R-HSA-9666946)
APC E941* [cytosol]
(R-HSA-9666947)
APC Q1303* [cytosol]
(R-HSA-9666972)
APC S943* [cytosol]
(R-HSA-9666973)
APC E1306* [cytosol]
(R-HSA-9666975)
APC S895* [cytosol]
(R-HSA-9666969)
APC S1315* [cytosol]
(R-HSA-9666970)
APC G1412* [cytosol]
(R-HSA-9666971)
APC Y1376* [cytosol]
(R-HSA-9666964)
APC Q886* [cytosol]
(R-HSA-9666965)
APC S1392* [cytosol]
(R-HSA-9666966)
APC S1539* [cytosol]
(R-HSA-9666967)
APC E1451* [cytosol]
(R-HSA-9666960)
APC E1397* [cytosol]
(R-HSA-9666961)
APC Q1406* [cytosol]
(R-HSA-9666962)
APC E1544* [cytosol]
(R-HSA-9666963)
APC F1197* [cytosol]
(R-HSA-5246655)
APC Q1338* [cytosol]
(R-HSA-5246654)
APC S811* [cytosol]
(R-HSA-5246652)
APC I1417 fs*2 [cytosol]
(R-HSA-5246651)
APC E1554* [cytosol]
(R-HSA-5246648)
p-ub-APC [cytosol]
(R-HSA-3009421)
K63polyUb-APC [cytosol]
(R-HSA-5246690)
APC [nucleoplasm]
(R-HSA-3361755)
APC(1-777) [cytosol]
(R-HSA-2976014)
APC(778-2843) [cytosol]
(R-HSA-2976013)
APC [cytosol]
(R-HSA-2976015)
0.725
15
UniProt:O15169 AXIN1
11
AXIN1 Y346* [cytosol]
(R-HSA-4839753)
AXIN1 L396M [cytosol]
(R-HSA-5251503)
AXIN1 E406* [cytosol]
(R-HSA-5251500)
AXIN1 W247* [cytosol]
(R-HSA-5251512)
AXIN1 P354L [cytosol]
(R-HSA-5251511)
AXIN1 P255S [cytosol]
(R-HSA-5251505)
ub-AXIN1 [cytosol]
(R-HSA-4641133)
AXIN1 [cytosol]
(R-HSA-195249)
p-T519,S524,S531-AXIN1 [cytosol]
(R-HSA-206040)
RibC-AXIN1 [cytosol]
(R-HSA-3640841)
Ub-RibC-AXIN1 [cytosol]
(R-HSA-3640864)
0.709
4
UniProt:Q5JTC6 AMER1
5
AMER1 S210* [cytosol]
(R-HSA-5251492)
AMER1 R497* [cytosol]
(R-HSA-9663943)
AMER1 R358* [cytosol]
(R-HSA-4839640)
AMER1 R353* [cytosol]
(R-HSA-9663939)
AMER1 [cytosol]
(R-HSA-1504189)
0.708
7
UniProt:P49674 CSNK1E
2
CSNK1E [nucleoplasm]
(R-HSA-421306)
CSNK1E [cytosol]
(R-HSA-205877)
0.687
5
UniProt:P49840 GSK3A
3
p-S21-GSK3A [cytosol]
(R-HSA-198352)
GSK3A [cytosol]
(R-HSA-198326)
p-Y279-GSK3A [cytosol]
(R-HSA-9635490)
0.669
3
UniProt:P14923 JUP
6
JUP [cornified envelope]
(R-HSA-8847739)
JUP [cytosol]
(R-HSA-201598)
JUP [specific granule lumen]
(R-HSA-6799534)
JUP [extracellular region]
(R-HSA-6806309)
JUP [ficolin-1-rich granule lumen]
(R-HSA-6801028)
JUP [plasma membrane]
(R-HSA-437260)
0.666
4
UniProt:P67775 PPP2CA
4
PPP2CA [cytosol]
(R-HSA-165971)
p-Y307-PPP2CA [cytosol]
(R-HSA-8857939)
PPP2CA [nucleoplasm]
(R-HSA-165978)
MeL-PPP2CA [nucleoplasm]
(R-HSA-8857791)
0.643
4
UniProt:P48729 CSNK1A1
2
CSNK1A1 [cilium]
(R-HSA-5632507)
CSNK1A1 [cytosol]
(R-HSA-195263)
0.643
4
UniProt:Q9H7D7 WDR26
0.641
4
UniProt:P01106 MYC
2
PolyUb-MYC [nucleoplasm]
(R-HSA-6783169)
MYC [nucleoplasm]
(R-HSA-188379)
0.623
10
UniProt:O14641 DVL2
5
p-DVL2 [cytosol]
(R-HSA-201706)
pp-DVL2 [cytosol]
(R-HSA-3772398)
p-DVL2 [clathrin-coated endocytic vesicle]
(R-HSA-5138444)
DVL2 [cytosol]
(R-HSA-201694)
ub-DVL2 [cytosol]
(R-HSA-4652689)
0.59
3
UniProt:Q9UKB1 FBXW11
1
FBXW11 [cytosol]
(R-HSA-976035)
0.558
4
UniProt:Q7Z699 SPRED1
2
SPRED1 [cytosol]
(R-HSA-5654207)
SPRED1 [plasma membrane]
(R-HSA-5658225)
0.556
3
UniProt:Q9BQ66 KR412
0.556
3
UniProt:Q99750 MDFI
0.556
3
UniProt:Q96KG9-4 SCYL1
0.556
3
UniProt:O94972 TRIM37
1
TRIM37 [cytosol]
(R-HSA-976049)
0.556
3
UniProt:Q9C019 TRI15
0.556
3
UniProt:Q9UJV3-2 MID2
0.556
3
UniProt:Q969G2 LHX4
1
LHX4 [nucleoplasm]
(R-HSA-9010585)
0.556
3
IntAct:EBI-16436498 CCSB ORF ID
0.556
3
UniProt:Q9BYR5 KRTAP4-2
1
KRTAP4-2 [cytosol]
(R-HSA-6809948)
0.556
3
UniProt:Q9H257-2 CARD9
0.556
3
UniProt:Q13137 CACO2
0.556
3
UniProt:Q5JR59-3 MTUS2
0.556
3
UniProt:O43586 PSTPIP1
1
PSTPIP1 [cytosol]
(R-HSA-879220)
0.556
3
IntAct:EBI-16436244 CCSB ORF ID
0.556
3
IntAct:EBI-16434222 CCSB ORF ID
0.556
3
UniProt:O75558 STX11
0.556
3
UniProt:Q96K21-3 ZFYVE19
0.556
3
UniProt:Q2TAC2-2 CCDC57
0.556
3
IntAct:EBI-16437007 CCSB ORF ID
0.556
3
UniProt:Q9UBB9 TFIP11
1
TFIP11 [nucleoplasm]
(R-HSA-8869310)
0.556
3
IntAct:EBI-16429620 CCSB ORF ID
0.556
3
UniProt:Q15654 TRIP6
0.556
6
UniProt:Q9HCK0 ZBT26
0.556
3
UniProt:G2XKQ0 SUMO5
0.556
3
UniProt:P63165 SUMO1
155
TOPORS-G97-SUMO1 [nucleoplasm]
(R-HSA-4551623)
K14-UBE2I-G97-SUMO1 [nucleoplasm]
(R-HSA-4085334)
PIAS4-G97-SUMO1 [nucleoplasm]
(R-HSA-3968375)
K2592-RANBP2-G97-SUMO1 [nuclear envelope]
(R-HSA-4551627)
K2723-RANBP2-G97-SUMO1 [nuclear envelope]
(R-HSA-4551737)
K2650-RANBP2-G97-SUMO1 [nuclear envelope]
(R-HSA-4551591)
K196-VHL-G97-SUMO1 [nucleoplasm]
(R-HSA-4551630)
K171-VHL-G97-SUMO1 [nucleoplasm]
(R-HSA-4551632)
K159-VHL-G97-SUMO1 [nucleoplasm]
(R-HSA-4551713)
MDM-G97-SUMO1 [nucleoplasm]
(R-HSA-3730829)
K575-TRIM28-G97-SUMO1 [nucleoplasm]
(R-HSA-4090305)
K804-TRIM28-G97-SUMO1 [nucleoplasm]
(R-HSA-3782561)
K750-TRIM28-G97-SUMO1 [nucleoplasm]
(R-HSA-4090298)
K676-TRIM28-G97-SUMO1 [nucleoplasm]
(R-HSA-4090396)
K554-TRIM28-G97-SUMO1 [nucleoplasm]
(R-HSA-3782555)
K779-TRIM28-G97-SUMO1 [nucleoplasm]
(R-HSA-3782585)
ING2-G97-SUMO1 [nucleoplasm]
(R-HSA-4086096)
K788-Ncoa2-G97-SUMO1 [nucleoplasm]
(R-HSA-4085297)
K731-Ncoa2-G97-SUMO1 [nucleoplasm]
(R-HSA-4085312)
K239-Ncoa2-G97-SUMO1 [nucleoplasm]
(R-HSA-4085320)
K239-NCOA2-G97-SUMO1 [nucleoplasm]
(R-HSA-4085299)
K731-NCOA2-G97-SUMO1 [nucleoplasm]
(R-HSA-4085290)
K788-NCOA2-G97-SUMO1 [nucleoplasm]
(R-HSA-4085308)
NPM1-G97-SUMO1 [nucleoplasm]
(R-HSA-4086019)
NCOR2-G97-SUMO1 [nucleoplasm]
(R-HSA-3927883)
DDX17-G97-SUMO1 [nucleoplasm]
(R-HSA-3900210)
PARK7-G97-SUMO1 [nucleoplasm]
(R-HSA-4085344)
K1033-CREBBP-G97-SUMO1 [nucleoplasm]
(R-HSA-3927910)
K1056-CREBBP-G97-SUMO1 [nucleoplasm]
(R-HSA-3927954)
K998-CREBBP-G97-SUMO1 [nucleoplasm]
(R-HSA-3927822)
K1154-NRIP1-G97-SUMO1 [nucleoplasm]
(R-HSA-4086067)
K756-NRIP1-G97-SUMO1 [nucleoplasm]
(R-HSA-4086034)
DDX5-G97-SUMO1 [nucleoplasm]
(R-HSA-3900212)
CASP8AP2-G97-SUMO1 [nucleoplasm]
(R-HSA-3927863)
K1024-EP300-G97-SUMO1 [nucleoplasm]
(R-HSA-3899298)
K1020-EP300-G97-SUMO1 [nucleoplasm]
(R-HSA-3899290)
CTBP1-G97-SUMO1 [nucleoplasm]
(R-HSA-3730764)
K231-SAFB-G97-SUMO1 [nucleoplasm]
(R-HSA-4085364)
K294-SAFB-G97-SUMO1 [nucleoplasm]
(R-HSA-4085341)
K624-MKL1-G97-SUMO1 [nucleoplasm]
(R-HSA-3900128)
K576-MKL1-G97-SUMO1 [nucleoplasm]
(R-HSA-3900225)
K499-MKL1-G97-SUMO1 [nucleoplasm]
(R-HSA-3900219)
K631-DAXX-G97-SUMO1 [nucleoplasm]
(R-HSA-4086044)
K630-DAXX-G97-SUMO1 [nucleoplasm]
(R-HSA-4086012)
SIN3A-G97-SUMO1 [nucleoplasm]
(R-HSA-4086058)
PPARGC1A-G97-SUMO1 [nucleoplasm]
(R-HSA-3903014)
HIPK2-G97-SUMO1 [nucleoplasm]
(R-HSA-4090362)
K774-NCOA1-G97-SUMO1 [nucleoplasm]
(R-HSA-4085292)
K732-NCOA1-G97-SUMO1 [nucleoplasm]
(R-HSA-4085278)
K538-MBD1-G97-SUMO1 [nucleoplasm]
(R-HSA-4090416)
K499-MBD1-G97-SUMO1 [nucleoplasm]
(R-HSA-4090332)
ZNF131-G97-SUMO1 [nucleoplasm]
(R-HSA-3730875)
K90-NFKB2-G97-SUMO1 [cytosol]
(R-HSA-4755511)
K689-NFKB2-G97-SUMO1 [cytosol]
(R-HSA-4755446)
K863-NFKB2-G97-SUMO1 [cytosol]
(R-HSA-4755412)
K298-NFKB2-G97-SUMO1 [cytosol]
(R-HSA-4755505)
p-S172-IKBKE-G97-SUMO1 [nucleoplasm]
(R-HSA-4755408)
K309-IKBKG-G97-SUMO1 [nucleoplasm]
(R-HSA-4755404)
K277-IKBKG-G97-SUMO1 [nucleoplasm]
(R-HSA-4755531)
NFKBIA-G97-SUMO1 [nucleoplasm]
(R-HSA-4656987)
AURKA-G97-SUMO1 [cytosol]
(R-HSA-4655413)
TOP2B-G97-SUMO1 [nucleoplasm]
(R-HSA-4641311)
TOP1-G97-SUMO1 [nucleoplasm]
(R-HSA-4641306)
TOP2A-G97-SUMO1 [nucleoplasm]
(R-HSA-4641341)
K254-PCNA-G97-SUMO1 [nucleoplasm]
(R-HSA-4615853)
K-PCNA-G97-SUMO1 [nucleoplasm]
(R-HSA-4615836)
K164-PCNA-G97-SUMO1 [nucleoplasm]
(R-HSA-4615951)
MDC1-G97-SUMO1 [nucleoplasm]
(R-HSA-4570527)
STAG2-G97-SUMO1 [nucleoplasm]
(R-HSA-3826645)
RAD21-G97-SUMO1 [nucleoplasm]
(R-HSA-3826574)
K411-RAD52-G97-SUMO1 [nucleoplasm]
(R-HSA-4568857)
K412-RAD52-G97-SUMO1 [nucleoplasm]
(R-HSA-4568850)
K414-RAD52-G97-SUMO1 [nucleoplasm]
(R-HSA-4568900)
XRCC4-G97-SUMO1 [nucleoplasm]
(R-HSA-4568869)
K160-PML-G97-SUMO1 [nucleoplasm]
(R-HSA-3730884)
K490-PML-G97-SUMO1 [nucleoplasm]
(R-HSA-3730833)
K65-PML-G97-SUMO1 [nucleoplasm]
(R-HSA-3730879)
K203-PARP1-G97-SUMO1 [nucleoplasm]
(R-HSA-4551625)
K486-PARP1-G97-SUMO1 [nucleoplasm]
(R-HSA-4551748)
K496-WRN-G97-SUMO1 [nucleoplasm]
(R-HSA-4568906)
K898-WRN-G97-SUMO1 [nucleoplasm]
(R-HSA-4568893)
K356-WRN-G97-SUMO1 [nucleoplasm]
(R-HSA-4568845)
RNF168-SUMO1 [nucleoplasm]
(R-HSA-4551631)
XPC-G97-SUMO1 [nucleoplasm]
(R-HSA-4570452)
TDG-G97-SUMO1 [nucleoplasm]
(R-HSA-4551682)
SP100-G97-SUMO1 [nucleoplasm]
(R-HSA-3730794)
BRCA1-G97-SUMO1 [nucleoplasm]
(R-HSA-3730735)
RXRA-G97-SUMO1 [nucleoplasm]
(R-HSA-4341090)
NR5A2-G97-SUMO1 [nucleoplasm]
(R-HSA-4755424)
K386-AR-G97-SUMO1 [nucleoplasm]
(R-HSA-4090321)
K520-AR-G97-SUMO1 [nucleoplasm]
(R-HSA-4090352)
K293-NR3C1-G97-SUMO1 [nucleoplasm]
(R-HSA-4341110)
K277-NR3C1-G97-SUMO1 [nucleoplasm]
(R-HSA-4341057)
K389-THRA-G97-SUMO1 [nucleoplasm]
(R-HSA-4719415)
K283-THRA-G97-SUMO1 [nucleoplasm]
(R-HSA-4719434)
K399-NR3C2-G97-SUMO1 [nucleoplasm]
(R-HSA-4341020)
K428-NR3C2-G97-SUMO1 [nucleoplasm]
(R-HSA-4341035)
K494-NR3C2-G97-SUMO1 [nucleoplasm]
(R-HSA-4341093)
K89-NR3C2-G97-SUMO1 [nucleoplasm]
(R-HSA-4341058)
K119-NR5A1-G97-SUMO1 [nucleoplasm]
(R-HSA-4546379)
K194-NR5A1-G97-SUMO1 [nucleoplasm]
(R-HSA-4546380)
NR2C1-G97-SUMO1 [nucleoplasm]
(R-HSA-4717492)
K303-ESR1-G97-SUMO1 [nucleoplasm]
(R-HSA-4090373)
K266-ESR1-G97-SUMO1 [nucleoplasm]
(R-HSA-4090359)
K302-ESR1-G97-SUMO1 [nucleoplasm]
(R-HSA-4090363)
K299-ESR1-G97-SUMO1 [nucleoplasm]
(R-HSA-4090349)
K268-ESR1-G97-SUMO1 [nucleoplasm]
(R-HSA-4090414)
K531-PGR-G97-SUMO1 [nucleoplasm]
(R-HSA-4341021)
K7-PGR-G97-SUMO1 [nucleoplasm]
(R-HSA-4341052)
K388-PGR-G97-SUMO1 [nucleoplasm]
(R-HSA-4341056)
K132-NR1H4-G97-SUMO1 [nucleoplasm]
(R-HSA-9610527)
NR1H4-G97-SUMO1 [nucleoplasm]
(R-HSA-4755434)
PPARG-G97-SUMO1 [nucleoplasm]
(R-HSA-4717445)
K395-PPARG-G97-SUMO1 [nucleoplasm]
(R-HSA-4717446)
PPARA-G97-SUMO1 [nucleoplasm]
(R-HSA-4341069)
K443-THRB-G97-SUMO1 [nucleoplasm]
(R-HSA-4719431)
K146-THRB-G97-SUMO1 [nucleoplasm]
(R-HSA-4719410)
K50-THRB-G97-SUMO1 [nucleoplasm]
(R-HSA-4719401)
RORA-G97-SUMO1 [nucleoplasm]
(R-HSA-4719426)
HIC1-G97-SUMO1 [nucleoplasm]
(R-HSA-4570544)
TP53BP1-G97-SUMO1 [nucleoplasm]
(R-HSA-3730731)
SP3-G97-SUMO1 [nucleoplasm]
(R-HSA-3730646)
K423-MITF-G97-SUMO1 [nucleoplasm]
(R-HSA-3730755)
K289-MITF-G97-SUMO1 [nucleoplasm]
(R-HSA-3730738)
K25-FOXL2-G97-SUMO1 [nucleoplasm]
(R-HSA-3968400)
K150-FOXL2-G97-SUMO1 [nucleoplasm]
(R-HSA-3968382)
K114-FOXL2-G97-SUMO1 [nucleoplasm]
(R-HSA-3968396)
HNRNPC-G97-SUMO1 [nucleoplasm]
(R-HSA-4570515)
K497-NOP58-G97-SUMO1 [nucleoplasm]
(R-HSA-4570504)
K467-NOP58-G97-SUMO1 [nucleoplasm]
(R-HSA-4570462)
DNMT3B-G97-SUMO1 [nucleoplasm]
(R-HSA-4655444)
DNMT3A-G97-SUMO1 [nucleoplasm]
(R-HSA-4655383)
DNMT1-G97-SUMO1 [nucleoplasm]
(R-HSA-4655358)
K84-CBX5-G97-SUMO1 [nucleoplasm]
(R-HSA-4615838)
K-CBX5-G97-SUMO1 [nucleoplasm]
(R-HSA-4615955)
K476-HDAC1-G97-SUMO1 [nucleoplasm]
(R-HSA-4615867)
K444-HDAC1-G97-SUMO1 [nucleoplasm]
(R-HSA-4616028)
CBX4-G97-SUMO1 [nucleoplasm]
(R-HSA-4551756)
HDAC2-G97-SUMO1 [nucleoplasm]
(R-HSA-4616032)
SUZ12-G97-SUMO1 [nucleoplasm]
(R-HSA-4615961)
SATB1-G97-SUMO1 [nucleoplasm]
(R-HSA-4615877)
HDAC4-G97-SUMO1 [nucleoplasm]
(R-HSA-4615956)
K1971-CHD3-G97-SUMO1 [nucleoplasm]
(R-HSA-8956370)
HIST1H4-G97-SUMO1 [nucleoplasm]
(R-HSA-4570549)
BMI1-G97-SUMO1 [nucleoplasm]
(R-HSA-4551654)
TFAP2B-G97-SUMO1 [nucleoplasm]
(R-HSA-3730839)
TFAP2C-G97-SUMO1 [nucleoplasm]
(R-HSA-3730823)
TFAP2A-1-G97-SUMO1 [nucleoplasm]
(R-HSA-3730825)
UBE2I-G97-SUMO1 [cytosol]
(R-HSA-4656941)
RANGAP1-G97-SUMO1 [nucleoplasm]
(R-HSA-3730796)
SUMO1(2-101) [nucleoplasm]
(R-HSA-2990831)
SUMO1 [nucleoplasm]
(R-HSA-877304)
UBA2-G97-SUMO1 [nucleoplasm]
(R-HSA-3730616)
UBE2I-G97-SUMO1 [nucleoplasm]
(R-HSA-3730622)
HERC2-SUMO1 [nucleoplasm]
(R-HSA-4551761)
0.556
3
UniProt:Q6FHY5 Q6FHY5
0.556
3
UniProt:Q6A162 KRT40
1
KRT40 [cytosol]
(R-HSA-6809605)
0.556
3
UniProt:Q08379 GOLGA2
3
GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-2167933)
p-S37-GOLGA2 [Golgi membrane]
(R-HSA-2172179)
GOLGA2 [Golgi membrane]
(R-HSA-6808764)
0.556
3
UniProt:O15105 SMAD7
2
SMAD7 [cytosol]
(R-HSA-173478)
SMAD7 [nucleoplasm]
(R-HSA-178197)
0.556
8
UniProt:P14373 TRIM27
2
TRIM27 [cytosol]
(R-HSA-8851002)
TRIM27 [nucleoplasm]
(R-HSA-2997690)
0.556
3
UniProt:Q12933 TRAF2
5
K63polyUb-TRAF2 [nucleoplasm]
(R-HSA-8862194)
TRAF2 [nucleoplasm]
(R-HSA-8862199)
K63polyUb-TRAF2 [cytosol]
(R-HSA-8862193)
PolyUb-TRAF2 [cytosol]
(R-HSA-6782848)
TRAF2 [cytosol]
(R-HSA-66370)
0.556
3
UniProt:O75581 LRP6
8
p-S1490-LRP6 [plasma membrane]
(R-HSA-206156)
p-T1479,S1490,T1493-LRP6 [plasma membrane]
(R-HSA-205884)
LRP6 [early endosome membrane]
(R-HSA-5368481)
p-LRP6 [early endosome membrane]
(R-HSA-5368496)
LRP6N [extracellular region]
(R-HSA-5334021)
p-2S,S1490,2T-LRP6 [plasma membrane]
(R-HSA-1458894)
p-4S,3T,T1479,S1490,T1493-LRP6 [plasma membrane]
(R-HSA-1458895)
LRP6 [plasma membrane]
(R-HSA-206252)
0.527
9
UniProt:Q93008 USP9X
1
USP9X [cytosol]
(R-HSA-870499)
0.527
2
IntAct:EBI-11789122 GSK3A
0.525
2
UniProt:G1T8E2 G1T8E2
0.525
2
UniProt:Q92837 FRAT1
1
FRAT1 [cytosol]
(R-HSA-1226051)
0.525
3
UniProt:Q5VWQ8-2 DAB2IP
0.524
2
UniProt:P62136 PPP1CA
1
PPP1CA [cytosol]
(R-HSA-163525)
0.524
4
UniProt:P04637 TP53
27
TP53 [cytosol]
(R-HSA-8869337)
Unfolded TP53 [cytosol]
(R-HSA-6813797)
PolyUb-TP53 [nucleoplasm]
(R-HSA-6782509)
SUMO2,3-K386-TP53 [nucleoplasm]
(R-HSA-2997661)
Me1-K372,p-S15,S20-TP53 [nucleoplasm]
(R-HSA-6805719)
Me2-K373-TP53 [nucleoplasm]
(R-HSA-6805759)
Me-K382,p-S15,S20-TP53 [nucleoplasm]
(R-HSA-3222124)
MeK-370,p-S15,S20-TP53 [nucleoplasm]
(R-HSA-3222226)
p-S15,S20,Me-R333,Me2-R335,R337-TP53 [nucleoplasm]
(R-HSA-6804378)
Me2K-370,382-TP53 [nucleoplasm]
(R-HSA-3222242)
p-S15,S33,S46-TP53 [nucleoplasm]
(R-HSA-6805268)
p-S15,S392-TP53 [nucleoplasm]
(R-HSA-3222015)
p-T55-TP53 [nucleoplasm]
(R-HSA-6805400)
p-S15,S20,S392-TP53 [nucleoplasm]
(R-HSA-6805053)
p-S15,S20,S269,T284-TP53 [nucleoplasm]
(R-HSA-6805133)
p-S315-TP53 [nucleoplasm]
(R-HSA-6805106)
Ac-K120,p-S15,S20-TP53 [nucleoplasm]
(R-HSA-6805656)
Ac-K120,K382,p-S15,S20-TP53 [nucleoplasm]
(R-HSA-6805631)
Ac-K382,p-S15,S20-TP53 [nucleoplasm]
(R-HSA-5628868)
p-S37-TP53 [nucleoplasm]
(R-HSA-3239022)
PolyUb,p-S15,S20-TP53 [nucleoplasm]
(R-HSA-6804446)
p-S15,S20,S46-TP53 [nucleoplasm]
(R-HSA-6798369)
PolyUb-TP53 [nucleoplasm]
(R-HSA-6793679)
PolyUb-TP53 [cytosol]
(R-HSA-6793681)
p-S15,S20-TP53 [nucleoplasm]
(R-HSA-69683)
p-S15-TP53 [nucleoplasm]
(R-HSA-69507)
TP53 [nucleoplasm]
(R-HSA-69488)
0.524
4
UniProt:P23258 TUBG1
1
TUBG1 [cytosol]
(R-HSA-379269)
0.512
4
UniProt:Q14194 CRMP1
4
CRMP1 [cytosol]
(R-HSA-398120)
p-Y-CRMP1 [cytosol]
(R-HSA-399784)
p-T509,T514,S518,S522-CRMP1 [cytosol]
(R-HSA-399777)
p-S522-CRMP1 [cytosol]
(R-HSA-399779)
0.508
2
UniProt:P39687 ANP32A
1
ANP32A [nucleoplasm]
(R-HSA-450467)
0.508
2
UniProt:P46937 YAP1
7
p-Y-YAP1 [cytosol]
(R-HSA-8937843)
p-Y407-YAP1 [nucleoplasm]
(R-HSA-8956661)
p-Y-YAP1 [nucleoplasm]
(R-HSA-8937857)
p-5S-YAP1 [cytosol]
(R-HSA-2028554)
p-S127-YAP1 [cytosol]
(R-HSA-2028553)
YAP1 [cytosol]
(R-HSA-1253345)
YAP1 [nucleoplasm]
(R-HSA-1253322)
0.499
11
UniProt:Q15583 TGIF1
1
TGIF1 [nucleoplasm]
(R-HSA-2186594)
0.499
4
UniProt:Q60953-2 PML
0.499
2
UniProt:P49407 ARRB1
5
PolyUb-ARRB1 [cytosol]
(R-HSA-6783186)
ARRB1 [cytosol]
(R-HSA-264470)
ARRB1 [lysosomal membrane]
(R-HSA-432701)
ARRB1 [Golgi membrane]
(R-HSA-350831)
ARRB1 [cytoplasmic vesicle membrane]
(R-HSA-351187)
0.499
2
UniProt:P35813 PPM1A
2
PPM1A [cytosol]
(R-HSA-380928)
PPM1A [nucleoplasm]
(R-HSA-205813)
0.499
2
UniProt:P29590 PML
5
SUMO2-K65,K160,K490-PML [nucleoplasm]
(R-HSA-3000423)
SUMO3-K65,K160,K490-PML [nucleoplasm]
(R-HSA-3000386)
SUMO1-K65,160,490-PML [nucleoplasm]
(R-HSA-3000440)
PML [cytosol]
(R-HSA-5624327)
PML [nucleoplasm]
(R-HSA-1031706)
0.463
2
UniProt:Q99ML9 Rnf111
3
Rnf111 [nucleoplasm]
(R-MMU-2186735)
Rnf111 [cytosol]
(R-MMU-975981)
Rnf111 [nucleoplasm]
(R-MMU-2186765)
0.463
5
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